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Registro Completo |
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Biblioteca(s): |
Embrapa Agroindústria de Alimentos. |
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Data corrente: |
21/05/2021 |
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Data da última atualização: |
15/06/2021 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
NIGRA, A. D.; GUIMAREAES, D. de A. B.; PRUCCA, C. G.; FREITAS-SILVA, O.; TEODORO, A. J.; GIL, G. A. |
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Afiliação: |
AYELÉN D. NIGRA, Universidad Nacional de Córdoba; DEBORAH DE ALMEIDA BAUER GUIMARÃES, Universidade Federal do Estado do Rio de Janeiro -UNIRIO; CÉSAR G. PRUCCA, Universidad Nacional de Córdoba; OTNIEL FREITAS SILVA, CTAA; ANDERSON J. TEODORO, Universidade Federal do Estado do Rio de Janeiro - UNIRIO; GERMÁN A. GIL, Universidad Nacional de Córdoba. |
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Título: |
Antitumor Effects of Freeze-Dried Robusta Coffee (Coffea canephora) Extracts on Breast Cancer Cell Lines. |
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Ano de publicação: |
2021 |
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Fonte/Imprenta: |
Oxidative Medicine and Cellular Longevity, 2021, ID 5572630, p. 1-16. |
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DOI: |
https://doi.org/10.1155/2021/5572630 |
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Idioma: |
Inglês |
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Notas: |
Research Article. |
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Conteúdo: |
Coffee consumption is believed to have chemopreventive and chemotherapeutic effects and to contribute to preventing thedevelopment and progression of cancer. However, there is still controversy around these claims. As indicated in our previousworks, diet can influence the risk of breast cancer. Intake of coffee is hypothesized to reduce this risk, but current scientificevidence is not conclusive. This work is aimed at studying the effects of Robusta coffee bean extract on cell viability,proliferation, and apoptosis of different human cancers, especially breast cancer cell lines. To this end, cell viability wasevaluated by Alamar Blue in 2D and 3D models, the cell cycle by PI, apoptosis by annexin V, mitochondrial morphology, andfunctionality by mitoTracker, and colony formation capacity by the clonogenic assay. Green and dark coffee extract significantlyreduced viability in human breast, colorectal, brain, and bone cancer cells. Coffee anticancer activity was clearly evidenced inMDA-MB-231 (ER-) and MCF-7 (ER+) breast cancer cells but not in the normal breast cell line. In addition, coffee extractinduces an increase S phase and a decrease G2/M population in breast cancer cells, affected the mitochondrial morphology, andtriggered apoptosis. MDA-MB-231 breast cancer cells lost their clonogenic capacity after treatment. The antitumor activity wasdemonstrated in both 2D and 3D culture cell models |
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Thesagro: |
Café Robusta; Câncer; Extrato Vegetal; Grão; Produto de Origem Vegetal. |
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Thesaurus Nal: |
Food technology. |
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Categoria do assunto: |
-- |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/223364/1/Antitumor-Effects-of-Freeze-Dried-Robusta-Coffee-Coffea-canephora-Extracts-on-Breast-Cancer-Cell-Lines.pdf
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Marc: |
LEADER 02271naa a2200277 a 4500
001 2131938
005 2021-06-15
008 2021 bl uuuu u00u1 u #d
024 7 $ahttps://doi.org/10.1155/2021/5572630$2DOI
100 1 $aNIGRA, A. D.
245 $aAntitumor Effects of Freeze-Dried Robusta Coffee (Coffea canephora) Extracts on Breast Cancer Cell Lines.$h[electronic resource]
260 $c2021
500 $aResearch Article.
520 $aCoffee consumption is believed to have chemopreventive and chemotherapeutic effects and to contribute to preventing thedevelopment and progression of cancer. However, there is still controversy around these claims. As indicated in our previousworks, diet can influence the risk of breast cancer. Intake of coffee is hypothesized to reduce this risk, but current scientificevidence is not conclusive. This work is aimed at studying the effects of Robusta coffee bean extract on cell viability,proliferation, and apoptosis of different human cancers, especially breast cancer cell lines. To this end, cell viability wasevaluated by Alamar Blue in 2D and 3D models, the cell cycle by PI, apoptosis by annexin V, mitochondrial morphology, andfunctionality by mitoTracker, and colony formation capacity by the clonogenic assay. Green and dark coffee extract significantlyreduced viability in human breast, colorectal, brain, and bone cancer cells. Coffee anticancer activity was clearly evidenced inMDA-MB-231 (ER-) and MCF-7 (ER+) breast cancer cells but not in the normal breast cell line. In addition, coffee extractinduces an increase S phase and a decrease G2/M population in breast cancer cells, affected the mitochondrial morphology, andtriggered apoptosis. MDA-MB-231 breast cancer cells lost their clonogenic capacity after treatment. The antitumor activity wasdemonstrated in both 2D and 3D culture cell models
650 $aFood technology
650 $aCafé Robusta
650 $aCâncer
650 $aExtrato Vegetal
650 $aGrão
650 $aProduto de Origem Vegetal
700 1 $aGUIMAREAES, D. de A. B.
700 1 $aPRUCCA, C. G.
700 1 $aFREITAS-SILVA, O.
700 1 $aTEODORO, A. J.
700 1 $aGIL, G. A.
773 $tOxidative Medicine and Cellular Longevity, 2021, ID 5572630, p. 1-16.
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Registro original: |
Embrapa Agroindústria de Alimentos (CTAA) |
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Registro |
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Registro Completo
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Biblioteca(s): |
Embrapa Acre. |
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Data corrente: |
23/04/2018 |
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Data da última atualização: |
02/07/2021 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
B - 2 |
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Autoria: |
SANTOS, R. S.; DELABIE, J. H. C. |
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Afiliação: |
RODRIGO SOUZA SANTOS, CPAF-Acre; Jacques Hubert Charles Delabie, Centro de Pesquisas do Cacau/Universidade Estadual de Santa Cruz. |
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Título: |
Epigaeic ants ina forest remnant in the state of Acre, Brazil and new records for the state. |
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Ano de publicação: |
2018 |
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Fonte/Imprenta: |
Brazilian Journal of Agriculture, v. 93, n. 1, p. 24-32, 2018. |
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ISSN: |
2318-2407 |
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Idioma: |
Português |
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Conteúdo: |
Ants are considered an important group of invertebrates in terrestrial ecosystems, where they participate in important ecological processes between animals and plants, and they are considered good indicators of environmental impacts as well. Although the diversity of ants in the Amazon biome is already relatively well known, the ant fauna in the state of Acre, Brazil is still poorly known. The aim of this study was to carry out a survey of ants in a forest remnant located in the municipality of Plácido de Castro, Acre, using pitfall traps. Thirty-six species of ants were collected from six subfamilies and 18 genera. From the species confirmed, 11 (Cephalotes serraticeps, Gnamptogenys moelleri, Gnamptogenys triangularis, Neoponera apicalis, Neoponera commutata, Neoponera verenae, Mayaponera constricta, Megalomyrmex emeryi, Pachycondyla impressa, Pheidole araneoides and Odontomachus caelatus) are first records for Acre state, increasing our knowledge of the epigaeic ants that occur in this region of the Amazon. As formigas são consideradas um significante grupo de invertebrados nos ecossistemas terrestres, participando de importantes processos ecológicos entre animais e plantas, além de serem consideradas como bons indicadores de impactos ambientais. Apesar de a diversidade de formigas no bioma Amazônico já ser relativamente bem conhecida, a fauna de formigas do estado do Acre ainda é incipientemente estudada. O objetivo deste estudo foi realizar um levantamento de formigas em um remanescente florestal localizado no município de Plácido de Castro - Acre, utilizando armadilhas do tipo "pitfall trap". Foram coletadas 36 espécies de formigas, pertencentes a seis subfamílias e 18 gêneros. Das espécies confirmadas, 11 (Cephalotes serraticeps, Gnamptogenys moelleri, Gnamptogenys triangularis, Neoponera apicalis, Neoponera commutata, Neoponera verenae, Mayaponera constricta, Megalomyrmex emeryi, Pachycondyla impressa, Pheidole araneoides e Odontomachus caelatus) representam primeiros registros para o estado do Acre, aumentando o conhecimento acerca das formigas epigeias que ocorrem nesta região da Amazônia. MenosAnts are considered an important group of invertebrates in terrestrial ecosystems, where they participate in important ecological processes between animals and plants, and they are considered good indicators of environmental impacts as well. Although the diversity of ants in the Amazon biome is already relatively well known, the ant fauna in the state of Acre, Brazil is still poorly known. The aim of this study was to carry out a survey of ants in a forest remnant located in the municipality of Plácido de Castro, Acre, using pitfall traps. Thirty-six species of ants were collected from six subfamilies and 18 genera. From the species confirmed, 11 (Cephalotes serraticeps, Gnamptogenys moelleri, Gnamptogenys triangularis, Neoponera apicalis, Neoponera commutata, Neoponera verenae, Mayaponera constricta, Megalomyrmex emeryi, Pachycondyla impressa, Pheidole araneoides and Odontomachus caelatus) are first records for Acre state, increasing our knowledge of the epigaeic ants that occur in this region of the Amazon. As formigas são consideradas um significante grupo de invertebrados nos ecossistemas terrestres, participando de importantes processos ecológicos entre animais e plantas, além de serem consideradas como bons indicadores de impactos ambientais. Apesar de a diversidade de formigas no bioma Amazônico já ser relativamente bem conhecida, a fauna de formigas do estado do Acre ainda é incipientemente estudada. O objetivo deste estudo foi realizar um levantamento de formigas em... Mostrar Tudo |
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Palavras-Chave: |
Acre; Amazonia Occidental; Amazônia Ocidental; Ants; First record; Hormigas; Plácido de Castro (AC); Plagas de plantas; Primeiro registro; Primer registro; Remanescente florestal; Sondeo de la población actual; Trampas de suelo; Western Amazon. |
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Thesagro: |
Armadilha; Formiga; Levantamento populacional; Praga de planta. |
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Thesaurus NAL: |
Current population survey; Formicidae; Pitfall traps; Plant pests. |
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Categoria do assunto: |
O Insetos e Entomologia |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/175799/1/26606.pdf
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Marc: |
LEADER 03320naa a2200409 a 4500
001 2090789
005 2021-07-02
008 2018 bl uuuu u00u1 u #d
022 $a2318-2407
100 1 $aSANTOS, R. S.
245 $aEpigaeic ants ina forest remnant in the state of Acre, Brazil and new records for the state.$h[electronic resource]
260 $c2018
520 $aAnts are considered an important group of invertebrates in terrestrial ecosystems, where they participate in important ecological processes between animals and plants, and they are considered good indicators of environmental impacts as well. Although the diversity of ants in the Amazon biome is already relatively well known, the ant fauna in the state of Acre, Brazil is still poorly known. The aim of this study was to carry out a survey of ants in a forest remnant located in the municipality of Plácido de Castro, Acre, using pitfall traps. Thirty-six species of ants were collected from six subfamilies and 18 genera. From the species confirmed, 11 (Cephalotes serraticeps, Gnamptogenys moelleri, Gnamptogenys triangularis, Neoponera apicalis, Neoponera commutata, Neoponera verenae, Mayaponera constricta, Megalomyrmex emeryi, Pachycondyla impressa, Pheidole araneoides and Odontomachus caelatus) are first records for Acre state, increasing our knowledge of the epigaeic ants that occur in this region of the Amazon. As formigas são consideradas um significante grupo de invertebrados nos ecossistemas terrestres, participando de importantes processos ecológicos entre animais e plantas, além de serem consideradas como bons indicadores de impactos ambientais. Apesar de a diversidade de formigas no bioma Amazônico já ser relativamente bem conhecida, a fauna de formigas do estado do Acre ainda é incipientemente estudada. O objetivo deste estudo foi realizar um levantamento de formigas em um remanescente florestal localizado no município de Plácido de Castro - Acre, utilizando armadilhas do tipo "pitfall trap". Foram coletadas 36 espécies de formigas, pertencentes a seis subfamílias e 18 gêneros. Das espécies confirmadas, 11 (Cephalotes serraticeps, Gnamptogenys moelleri, Gnamptogenys triangularis, Neoponera apicalis, Neoponera commutata, Neoponera verenae, Mayaponera constricta, Megalomyrmex emeryi, Pachycondyla impressa, Pheidole araneoides e Odontomachus caelatus) representam primeiros registros para o estado do Acre, aumentando o conhecimento acerca das formigas epigeias que ocorrem nesta região da Amazônia.
650 $aCurrent population survey
650 $aFormicidae
650 $aPitfall traps
650 $aPlant pests
650 $aArmadilha
650 $aFormiga
650 $aLevantamento populacional
650 $aPraga de planta
653 $aAcre
653 $aAmazonia Occidental
653 $aAmazônia Ocidental
653 $aAnts
653 $aFirst record
653 $aHormigas
653 $aPlácido de Castro (AC)
653 $aPlagas de plantas
653 $aPrimeiro registro
653 $aPrimer registro
653 $aRemanescente florestal
653 $aSondeo de la población actual
653 $aTrampas de suelo
653 $aWestern Amazon
700 1 $aDELABIE, J. H. C.
773 $tBrazilian Journal of Agriculture$gv. 93, n. 1, p. 24-32, 2018.
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Embrapa Acre (CPAF-AC) |
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