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Registro Completo |
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Biblioteca(s): |
Embrapa Pecuária Sudeste. |
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Data corrente: |
15/02/2019 |
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Data da última atualização: |
29/11/2019 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
VIGNATO B. S.; COUTINHO, L. L.; POLETI, M. D.; CESAR, A. S. M.; MONCAU, C. T.; REGITANO, L. C. de A.; BALIEIRO, J. C. C. |
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Afiliação: |
Bárbara Silva-Vignato, USP; Luiz L. Coutinho, USP; Mirele D. Poleti, USP; Aline S. M. Cesar, USP; Cristina T. Moncau, Universidade Federal de Lavras; LUCIANA CORREIA DE ALMEIDA REGITANO, CPPSE; Júlio C. C. Balieiro, USP. |
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Título: |
Gene co-expression networks associated with carcass traits reveal new pathways for muscle and fat deposition in Nelore cattle. |
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Ano de publicação: |
2019 |
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Fonte/Imprenta: |
Genomics, v. 20, n. 32, p. 2-13, 2019. |
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DOI: |
10.1186/s12864-018-5345-y |
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Idioma: |
Inglês |
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Conteúdo: |
Positively correlated with carcass weight and animal growth, the ribeye area (REA) and the backfat thickness (BFT) are economic important carcass traits, which impact directly on producer's payment. The selection of these traits has not been satisfactory since they are expressed later in the animal's life and multigene regulated. So, next-generation technologies have been applied in this area to improve animal's selection and better understand the molecular mechanisms involved in the development of these traits. Correlation network analysis, performed by tools like WGCNA (Weighted Correlation Network Analysis), has been used to explore gene-gene interactions and gene-phenotype correlations. Thus, this study aimed to identify putative candidate genes and metabolic pathways that regulate REA and BFT by constructing a gene co-expression network using WGCNA and RNA sequencing data, to better understand genetic and molecular variations behind these complex traits in Nelore cattle. |
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Palavras-Chave: |
Functional enrichment analysis; Ribeye area; RNA-Seq data; WGCNA. |
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Thesagro: |
Carcaça; Gado Nelore; Gordura Animal. |
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Thesaurus Nal: |
Backfat; Beef carcasses; Thickness. |
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Categoria do assunto: |
L Ciência Animal e Produtos de Origem Animal |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/192864/1/1-Gene-co-expression-networks-associatedwith-carcass-traits-reveal-new-pathways-formuscle-and-fat-deposition-in-Nelore-cattle.pdf
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Marc: |
LEADER 01936naa a2200325 a 4500
001 2106063
005 2019-11-29
008 2019 bl uuuu u00u1 u #d
024 7 $a10.1186/s12864-018-5345-y$2DOI
100 1 $aVIGNATO B. S.
245 $aGene co-expression networks associated with carcass traits reveal new pathways for muscle and fat deposition in Nelore cattle.$h[electronic resource]
260 $c2019
520 $aPositively correlated with carcass weight and animal growth, the ribeye area (REA) and the backfat thickness (BFT) are economic important carcass traits, which impact directly on producer's payment. The selection of these traits has not been satisfactory since they are expressed later in the animal's life and multigene regulated. So, next-generation technologies have been applied in this area to improve animal's selection and better understand the molecular mechanisms involved in the development of these traits. Correlation network analysis, performed by tools like WGCNA (Weighted Correlation Network Analysis), has been used to explore gene-gene interactions and gene-phenotype correlations. Thus, this study aimed to identify putative candidate genes and metabolic pathways that regulate REA and BFT by constructing a gene co-expression network using WGCNA and RNA sequencing data, to better understand genetic and molecular variations behind these complex traits in Nelore cattle.
650 $aBackfat
650 $aBeef carcasses
650 $aThickness
650 $aCarcaça
650 $aGado Nelore
650 $aGordura Animal
653 $aFunctional enrichment analysis
653 $aRibeye area
653 $aRNA-Seq data
653 $aWGCNA
700 1 $aCOUTINHO, L. L.
700 1 $aPOLETI, M. D.
700 1 $aCESAR, A. S. M.
700 1 $aMONCAU, C. T.
700 1 $aREGITANO, L. C. de A.
700 1 $aBALIEIRO, J. C. C.
773 $tGenomics$gv. 20, n. 32, p. 2-13, 2019.
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Registro original: |
Embrapa Pecuária Sudeste (CPPSE) |
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| 1. |  | VIGNATO B. S.; COUTINHO, L. L.; POLETI, M. D.; CESAR, A. S. M.; MONCAU, C. T.; REGITANO, L. C. de A.; BALIEIRO, J. C. C. Gene co-expression networks associated with carcass traits reveal new pathways for muscle and fat deposition in Nelore cattle. Genomics, v. 20, n. 32, p. 2-13, 2019.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
| Biblioteca(s): Embrapa Pecuária Sudeste. |
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