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Registro Completo |
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Biblioteca(s): |
Embrapa Agricultura Digital; Embrapa Pecuária Sudeste. |
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Data corrente: |
11/12/2018 |
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Data da última atualização: |
05/02/2019 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
SOUZA, M. M. de; ZERLOTINI NETO, A.; GEISTLINGER, L.; TIZIOTO, P. C.; TAYLOR, J. F.; ROCHA, M. I. P.; DINIZ, W. J. S.; COUTINHO, L. L.; REGITANO, L. C. de A. |
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Afiliação: |
MARCELA M. DE SOUZA, UFSCar; ADHEMAR ZERLOTINI NETO, CNPTIA; LUDWIG GEISTLINGER, CPPSE; POLYANA C. TIZIOTO, NGS Genomic Solution; JEREMY F. TAYLOR, University of Missouri; MARINA I. P. ROCHA, UFSCar; WELLISON J. S. DINIZ, UFSCar; LUIZ L. COUTINHO, USP; LUCIANA CORREIA DE ALMEIDA REGITANO, CPPSE. |
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Título: |
A comprehensive manually-curated compendium of bovine transcription factors. |
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Ano de publicação: |
2018 |
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Fonte/Imprenta: |
Scientific Reports, v. 8, p. 1-12, 2018. |
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DOI: |
10.1038/s41598-018-32146-2 |
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Idioma: |
Inglês |
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Notas: |
Article number: 13747. Na publicação: Adhemar Zerlotini, Luciana C. A. Regitano. |
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Conteúdo: |
Transcription factors (TFs) are pivotal regulatory proteins that control gene expression in a contextdependent and tissue-specific manner. In contrast to human, where comprehensive curated TF collections exist, bovine TFs are only rudimentary recorded and characterized. In this article, we present a manually-curated compendium of 865 sequence-specific DNA-binding bovines TFs, which we analyzed for domain family distribution, evolutionary conservation, and tissue-specific expression. In addition, we provide a list of putative transcription cofactors derived from known interactions with the identified TFs. Since there is a general lack of knowledge concerning the regulation of gene expression in cattle, the curated list of TF should provide a basis for an improved comprehension of regulatory mechanisms that are specific to the species. |
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Palavras-Chave: |
DNA bovine; DNA bovino; Expressão gênica; Gene expression in cattle. |
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Thesaurus Nal: |
Gene expression regulation. |
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Categoria do assunto: |
G Melhoramento Genético |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/189042/1/AP-Comprehensive-Adhemar-etal.pdf
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/188184/1/ComprehensiveManuallyCurated.pdf
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Marc: |
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024 7 $a10.1038/s41598-018-32146-2$2DOI
100 1 $aSOUZA, M. M. de
245 $aA comprehensive manually-curated compendium of bovine transcription factors.$h[electronic resource]
260 $c2018
500 $aArticle number: 13747. Na publicação: Adhemar Zerlotini, Luciana C. A. Regitano.
520 $aTranscription factors (TFs) are pivotal regulatory proteins that control gene expression in a contextdependent and tissue-specific manner. In contrast to human, where comprehensive curated TF collections exist, bovine TFs are only rudimentary recorded and characterized. In this article, we present a manually-curated compendium of 865 sequence-specific DNA-binding bovines TFs, which we analyzed for domain family distribution, evolutionary conservation, and tissue-specific expression. In addition, we provide a list of putative transcription cofactors derived from known interactions with the identified TFs. Since there is a general lack of knowledge concerning the regulation of gene expression in cattle, the curated list of TF should provide a basis for an improved comprehension of regulatory mechanisms that are specific to the species.
650 $aGene expression regulation
653 $aDNA bovine
653 $aDNA bovino
653 $aExpressão gênica
653 $aGene expression in cattle
700 1 $aZERLOTINI NETO, A.
700 1 $aGEISTLINGER, L.
700 1 $aTIZIOTO, P. C.
700 1 $aTAYLOR, J. F.
700 1 $aROCHA, M. I. P.
700 1 $aDINIZ, W. J. S.
700 1 $aCOUTINHO, L. L.
700 1 $aREGITANO, L. C. de A.
773 $tScientific Reports$gv. 8, p. 1-12, 2018.
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Registro original: |
Embrapa Agricultura Digital (CNPTIA) |
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| 1. |  | SOUZA, M. M. de; ZERLOTINI NETO, A.; GEISTLINGER, L.; TIZIOTO, P. C.; TAYLOR, J. F.; ROCHA, M. I. P.; DINIZ, W. J. S.; COUTINHO, L. L.; REGITANO, L. C. de A. A comprehensive manually-curated compendium of bovine transcription factors. Scientific Reports, v. 8, p. 1-12, 2018. Article number: 13747. Na publicação: Adhemar Zerlotini, Luciana C. A. Regitano.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
| Biblioteca(s): Embrapa Agricultura Digital; Embrapa Pecuária Sudeste. |
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