|
|
Registro Completo |
Biblioteca(s): |
Embrapa Suínos e Aves. |
Data corrente: |
11/05/2017 |
Data da última atualização: |
26/01/2018 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Autoria: |
GRUPIONI, N. V.; STAFUZZA, N. B.; CARVAJAL, A. B.; IBELLI, A. M. G.; PEIXOTO, J. de O.; LEDUR, M. C.; MUNARI, D. P. |
Afiliação: |
NATALIA VINHAL GRUPIONI, UNESP/Jaboticabal; NEDENIA BONVINO STAFUZZA, UNESP/Jaboticabal; ALEJANDRO BARRERA, UNESP/Jaboticabal; ADRIANA MERCIA GUARATINI IBELLI, CNPSA; JANE DE OLIVEIRA PEIXOTO, CNPSA; MONICA CORREA LEDUR, CNPSA; DANÍSIO PRADO MUNARI, UNESP/Jaboticabal. |
Título: |
Association of RUNX2 and TNFSF11 genes with production traits in a paternal broiler line. |
Ano de publicação: |
2017 |
Fonte/Imprenta: |
Genetics and Molecular Research, v. 16, n.1, 2017. |
DOI: |
http://dx.doi.org/10.4238/gmr16019443 |
Idioma: |
Inglês |
Conteúdo: |
Abstract: Intense selection for production traits has improved the genetic gain of important economic traits. However, selection for performance and carcass traits has led to the onset of locomotors problems and decreasing bone strength in broilers. Thus, genes associated with bone integrity traits have become candidates for genetic studies in order to reduce the impact of bone disorders in broilers. This study investigated the association of the RUNX2 and TNFSF11 genes with 79 traits related to performance, carcass composition, organs, and bone integrity in a paternal broiler line. Analyses of genetic association between single-nucleotide polymorphisms (SNPs) and traits were carried out using the maximum likelihood procedures for mixed models. Genetic associations (P < 0.05) were found between SNP g.124,883A>G in the RUNX2 gene and chilled femur weight (additive plus dominance deviation effects within sex) and with performance traits (additive within sex and additive effects). The SNP g.14,862T>C in the TNFSF11 gene presented genetic associations (P < 0.05) with additive plus dominance deviation effects within sex for performance traits. Suggestive genetic associations (P < 0.10) were found with abdominal fat and its yield. Selection based on SNPs g.14,862T>C in TNFSF11 and g.124,883A>G in RUNX2 could be used to improve performance and carcass quality traits in the population studied, although SNP g.14,862T>C was not in Hardy-Weinberg equilibrium because it was not undergoing a selection process. Furthermore, it is important to validate these markers in an unrelated population for use in the selection process. MenosAbstract: Intense selection for production traits has improved the genetic gain of important economic traits. However, selection for performance and carcass traits has led to the onset of locomotors problems and decreasing bone strength in broilers. Thus, genes associated with bone integrity traits have become candidates for genetic studies in order to reduce the impact of bone disorders in broilers. This study investigated the association of the RUNX2 and TNFSF11 genes with 79 traits related to performance, carcass composition, organs, and bone integrity in a paternal broiler line. Analyses of genetic association between single-nucleotide polymorphisms (SNPs) and traits were carried out using the maximum likelihood procedures for mixed models. Genetic associations (P < 0.05) were found between SNP g.124,883A>G in the RUNX2 gene and chilled femur weight (additive plus dominance deviation effects within sex) and with performance traits (additive within sex and additive effects). The SNP g.14,862T>C in the TNFSF11 gene presented genetic associations (P < 0.05) with additive plus dominance deviation effects within sex for performance traits. Suggestive genetic associations (P < 0.10) were found with abdominal fat and its yield. Selection based on SNPs g.14,862T>C in TNFSF11 and g.124,883A>G in RUNX2 could be used to improve performance and carcass quality traits in the population studied, although SNP g.14,862T>C was not in Hardy-Weinberg equilibrium because it was not undergoi... Mostrar Tudo |
Thesagro: |
Frango de corte; Melhoramento genético animal. |
Thesaurus Nal: |
Animal breeding; Broiler chickens. |
Categoria do assunto: |
-- |
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/159744/1/final8533.pdf
|
Marc: |
LEADER 02434naa a2200253 a 4500 001 2069536 005 2018-01-26 008 2017 bl uuuu u00u1 u #d 024 7 $ahttp://dx.doi.org/10.4238/gmr16019443$2DOI 100 1 $aGRUPIONI, N. V. 245 $aAssociation of RUNX2 and TNFSF11 genes with production traits in a paternal broiler line.$h[electronic resource] 260 $c2017 520 $aAbstract: Intense selection for production traits has improved the genetic gain of important economic traits. However, selection for performance and carcass traits has led to the onset of locomotors problems and decreasing bone strength in broilers. Thus, genes associated with bone integrity traits have become candidates for genetic studies in order to reduce the impact of bone disorders in broilers. This study investigated the association of the RUNX2 and TNFSF11 genes with 79 traits related to performance, carcass composition, organs, and bone integrity in a paternal broiler line. Analyses of genetic association between single-nucleotide polymorphisms (SNPs) and traits were carried out using the maximum likelihood procedures for mixed models. Genetic associations (P < 0.05) were found between SNP g.124,883A>G in the RUNX2 gene and chilled femur weight (additive plus dominance deviation effects within sex) and with performance traits (additive within sex and additive effects). The SNP g.14,862T>C in the TNFSF11 gene presented genetic associations (P < 0.05) with additive plus dominance deviation effects within sex for performance traits. Suggestive genetic associations (P < 0.10) were found with abdominal fat and its yield. Selection based on SNPs g.14,862T>C in TNFSF11 and g.124,883A>G in RUNX2 could be used to improve performance and carcass quality traits in the population studied, although SNP g.14,862T>C was not in Hardy-Weinberg equilibrium because it was not undergoing a selection process. Furthermore, it is important to validate these markers in an unrelated population for use in the selection process. 650 $aAnimal breeding 650 $aBroiler chickens 650 $aFrango de corte 650 $aMelhoramento genético animal 700 1 $aSTAFUZZA, N. B. 700 1 $aCARVAJAL, A. B. 700 1 $aIBELLI, A. M. G. 700 1 $aPEIXOTO, J. de O. 700 1 $aLEDUR, M. C. 700 1 $aMUNARI, D. P. 773 $tGenetics and Molecular Research$gv. 16, n.1, 2017.
Download
Esconder MarcMostrar Marc Completo |
Registro original: |
Embrapa Suínos e Aves (CNPSA) |
|
Biblioteca |
ID |
Origem |
Tipo/Formato |
Classificação |
Cutter |
Registro |
Volume |
Status |
URL |
Voltar
|
|
Registros recuperados : 1 | |
1. | | GRUPIONI, N. V.; STAFUZZA, N. B.; CARVAJAL, A. B.; IBELLI, A. M. G.; PEIXOTO, J. de O.; LEDUR, M. C.; MUNARI, D. P. Association of RUNX2 and TNFSF11 genes with production traits in a paternal broiler line. Genetics and Molecular Research, v. 16, n.1, 2017.Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 2 |
Biblioteca(s): Embrapa Suínos e Aves. |
| |
Registros recuperados : 1 | |
|
Nenhum registro encontrado para a expressão de busca informada. |
|
|