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Registro Completo |
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Biblioteca(s): |
Embrapa Suínos e Aves. |
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Data corrente: |
22/02/2017 |
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Data da última atualização: |
03/03/2023 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
ZANELLA, R.; MORES, N.; MORES, M. A. Z.; PEIXOTO, J. de O.; ZANELLA, E. L.; ZANELLA, J. R. C.; IBELLI, A. M. G.; GAVA, D.; CANTAO, M. E.; LEDUR, M. C. |
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Afiliação: |
RICARDO ZANELLA, UFP; NELSON MORES, CNPSA; MARCOS ANTONIO ZANELLA MORES, CNPSA; JANE DE OLIVEIRA PEIXOTO, CNPSA; UPF; JANICE REIS CIACCI ZANELLA, CNPSA; ADRIANA MERCIA GUARATINI IBELLI, CNPSA; DANIELLE GAVA, CNPSA; MAURICIO EGIDIO CANTAO, CNPSA; MONICA CORREA LEDUR, CNPSA. |
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Título: |
Genome-wide association study of periweaning failure-to-thrive syndrome (PFTS) in pigs. |
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Ano de publicação: |
2016 |
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Fonte/Imprenta: |
Veterinary Record, v. 178, n. 26, p. 1-7, 2016. |
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DOI: |
http://dx.doi.org/10.1136/vr.103546 |
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Idioma: |
Inglês |
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Conteúdo: |
Porcine periweaning-failure-to-thrive syndrome (PFTS) is a condition that affects newly weaned piglets. It is characterised by a progressive debilitation leading to death, in the absence of infectious, nutritional, management or environmental factors. In this study, we present the first report of PFTS in South America and the results of a genome-wide association study to identify the genetic markers associated with the appearance of this condition in a crossbred swine population. Four chromosomal regions were associated with PFTS predisposition, one located on SSCX, one on SSC8, and the two other regions on SSC14. Regions on SSC8 and SSC14 harbour important functional candidate genes involved in human depression and might have an important role in PFTS. Our findings contribute to the increasing knowledge about this syndrome, which has been investigated since 2007, and to the identification of the aetiology of this disease. |
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Palavras-Chave: |
Depression; Desmame; Genômica; GWAS; PFTS. |
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Thesagro: |
Genoma; Leitão. |
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Thesaurus Nal: |
Piglets; Weaning. |
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Categoria do assunto: |
-- |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/156408/1/final8212.pdf
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Marc: |
LEADER 01860naa a2200349 a 4500
001 2065162
005 2023-03-03
008 2016 bl uuuu u00u1 u #d
024 7 $ahttp://dx.doi.org/10.1136/vr.103546$2DOI
100 1 $aZANELLA, R.
245 $aGenome-wide association study of periweaning failure-to-thrive syndrome (PFTS) in pigs.$h[electronic resource]
260 $c2016
520 $aPorcine periweaning-failure-to-thrive syndrome (PFTS) is a condition that affects newly weaned piglets. It is characterised by a progressive debilitation leading to death, in the absence of infectious, nutritional, management or environmental factors. In this study, we present the first report of PFTS in South America and the results of a genome-wide association study to identify the genetic markers associated with the appearance of this condition in a crossbred swine population. Four chromosomal regions were associated with PFTS predisposition, one located on SSCX, one on SSC8, and the two other regions on SSC14. Regions on SSC8 and SSC14 harbour important functional candidate genes involved in human depression and might have an important role in PFTS. Our findings contribute to the increasing knowledge about this syndrome, which has been investigated since 2007, and to the identification of the aetiology of this disease.
650 $aPiglets
650 $aWeaning
650 $aGenoma
650 $aLeitão
653 $aDepression
653 $aDesmame
653 $aGenômica
653 $aGWAS
653 $aPFTS
700 1 $aMORES, N.
700 1 $aMORES, M. A. Z.
700 1 $aPEIXOTO, J. de O.
700 1 $aZANELLA, E. L.
700 1 $aZANELLA, J. R. C.
700 1 $aIBELLI, A. M. G.
700 1 $aGAVA, D.
700 1 $aCANTAO, M. E.
700 1 $aLEDUR, M. C.
773 $tVeterinary Record$gv. 178, n. 26, p. 1-7, 2016.
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Registro original: |
Embrapa Suínos e Aves (CNPSA) |
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| 1. |  | ZANELLA, R.; MORES, N.; MORES, M. A. Z.; PEIXOTO, J. de O.; ZANELLA, E. L.; ZANELLA, J. R. C.; IBELLI, A. M. G.; GAVA, D.; CANTAO, M. E.; LEDUR, M. C. Genome-wide association study of periweaning failure-to-thrive syndrome (PFTS) in pigs. Veterinary Record, v. 178, n. 26, p. 1-7, 2016.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: B - 1 |
| Biblioteca(s): Embrapa Suínos e Aves. |
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