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Registro Completo |
Biblioteca(s): |
Embrapa Meio Ambiente. |
Data corrente: |
27/05/1994 |
Data da última atualização: |
28/12/2016 |
Autoria: |
CASTRO, V. L. S. S. de; PALERMO-NETO, J. |
Afiliação: |
VERA LUCIA SCHERHOLZ S DE CASTRO, CNPMA; J. PALERMO-NETO, USP. |
Título: |
Effects of long-term aldrin administration on seizure susceptibility of rats. |
Ano de publicação: |
1989 |
Fonte/Imprenta: |
Pharmacology & Toxicology, v.65, p.204-208, 1989. |
Idioma: |
Inglês |
Conteúdo: |
The effects of long-term administration of sub-convulsive doses of aldrin, an organochlorinated pesticide, on seizure susceptibility of rats were studied. Results show that treatment with the pesticide made the rats more susceptible to sound-induced seizure; an increment in post-seizure depression time after maximal electroschock administration was also observed in aldrin-treated animals. Aldrin administration displaced the control dose-response curves constructed for amphetamine and pentylenetetrazol to the left and right, respectively; no differences were detected between control and aldrin-treated rats for strychnine, picrotoxin or 3-mercaptopropionic acid. The results, discussed in the light of the effects of aldrin on biogenic amines or on the electrophysiology of neurones suggested an involvement of both noradrenergic and alteration excitability of the CNS with the observed increments on seizure susceptibility. |
Palavras-Chave: |
Insecticide; Organochloride; Pesticide; Rat. |
Thesagro: |
Aldrin. |
Thesaurus Nal: |
toxicology. |
Categoria do assunto: |
-- |
Marc: |
LEADER 01500naa a2200205 a 4500 001 1011947 005 2016-12-28 008 1989 bl uuuu u00u1 u #d 100 1 $aCASTRO, V. L. S. S. de 245 $aEffects of long-term aldrin administration on seizure susceptibility of rats.$h[electronic resource] 260 $c1989 520 $aThe effects of long-term administration of sub-convulsive doses of aldrin, an organochlorinated pesticide, on seizure susceptibility of rats were studied. Results show that treatment with the pesticide made the rats more susceptible to sound-induced seizure; an increment in post-seizure depression time after maximal electroschock administration was also observed in aldrin-treated animals. Aldrin administration displaced the control dose-response curves constructed for amphetamine and pentylenetetrazol to the left and right, respectively; no differences were detected between control and aldrin-treated rats for strychnine, picrotoxin or 3-mercaptopropionic acid. The results, discussed in the light of the effects of aldrin on biogenic amines or on the electrophysiology of neurones suggested an involvement of both noradrenergic and alteration excitability of the CNS with the observed increments on seizure susceptibility. 650 $atoxicology 650 $aAldrin 653 $aInsecticide 653 $aOrganochloride 653 $aPesticide 653 $aRat 700 1 $aPALERMO-NETO, J. 773 $tPharmacology & Toxicology$gv.65, p.204-208, 1989.
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| Acesso ao texto completo restrito à biblioteca da Embrapa Amazônia Oriental. Para informações adicionais entre em contato com cpatu.biblioteca@embrapa.br. |
Registro Completo
Biblioteca(s): |
Embrapa Amazônia Oriental. |
Data corrente: |
24/04/2024 |
Data da última atualização: |
24/04/2024 |
Autoria: |
PINHEIRO, E. |
Afiliação: |
EURICO PINHEIRO, CPATU. |
Título: |
Aspectos fitotécnicos da nova heveicultura no Brasil. |
Ano de publicação: |
1979 |
Fonte/Imprenta: |
[Belém, PA: FCAP: Embrapa, 1979?]. |
Páginas: |
11 p. |
Idioma: |
Português |
Palavras-Chave: |
Heveiculture; Phytotechnics; Rubber tree. |
Thesagro: |
Fitotecnia; Heveicultura; Seringueira. |
Categoria do assunto: |
-- |
Marc: |
LEADER 00473nam a2200181 a 4500 001 2163863 005 2024-04-24 008 1979 bl uuuu u0uu1 u #d 100 1 $aPINHEIRO, E. 245 $aAspectos fitotécnicos da nova heveicultura no Brasil. 260 $a[Belém, PA: FCAP: Embrapa, 1979?].$c1979 300 $a11 p. 650 $aFitotecnia 650 $aHeveicultura 650 $aSeringueira 653 $aHeveiculture 653 $aPhytotechnics 653 $aRubber tree
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