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 | Acesso ao texto completo restrito à biblioteca da Embrapa Instrumentação. Para informações adicionais entre em contato com cnpdia.biblioteca@embrapa.br. |
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Registro Completo |
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Biblioteca(s): |
Embrapa Instrumentação. |
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Data corrente: |
20/04/2023 |
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Data da última atualização: |
15/01/2024 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
GOMES, N. O.; PASCHOALIN, R. T.; BILLATO, S.; SORIGOTTI, A. R.; FARINAS, C. S.; MATTOSO, L. H. C.; MACHADO, S. A. S.; OLIVEIRA JR., O. N.; RAYMUNDO-PEREIRA, P. A. |
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Afiliação: |
CRISTIANE SANCHEZ FARINAS, CNPDIA; LUIZ HENRIQUE CAPPARELLI MATTOSO, CNPDIA. |
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Título: |
Flexible, Bifunctional Sensing Platform Made with Biodegradable Mats for Detecting Glucose in Urine. |
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Ano de publicação: |
2023 |
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Fonte/Imprenta: |
ACS Sustainable Chemistry & Engineering, v. 11, 2023. |
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Páginas: |
2209–2218 |
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ISSN: |
2168-0485 |
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DOI: |
https://doi.org/10.1021/acssuschemeng.2c05438 |
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Idioma: |
Inglês |
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Conteúdo: |
: We report on a flexible, bifunctional platform made with solution-blow spinning fiber mats of polylactic acid (PLA) and polyethylene glycol (PEG). The PLA/PEG mats were designated bifunctional because they were used as a substrate for screenprinted carbon electrodes (SPCEs) and as a matrix to attach glucose oxidase (GOx)covalently. By attaching GOx only on the fiber mats, and not on the SPCE, the detectionof hydrogen peroxide generated from glucose oxidation by the enzyme was efficient,especially with Prussian blue (PB) nanoparticles electrodeposited on the SPCE surface.The bifunctional device detected hydrogen peroxide (H2O2) in synthetic and humanurine at a low applied potential (0 V vs Ag/AgCl) in the range from 1.0 to 6.0 mM, witha detection limit of 0.197 mM, being also interference-free. The biosensor whose cost is
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Palavras-Chave: |
Biodegradable and biocompatible mat; Glucose electrochemical biosensor; Polylactic acid (PLA); Solution-blow spinning; Urine non-invasive sample. |
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Categoria do assunto: |
-- |
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Marc: |
LEADER 02286naa a2200313 a 4500
001 2153278
005 2024-01-15
008 2023 bl uuuu u00u1 u #d
022 $a2168-0485
024 7 $ahttps://doi.org/10.1021/acssuschemeng.2c05438$2DOI
100 1 $aGOMES, N. O.
245 $aFlexible, Bifunctional Sensing Platform Made with Biodegradable Mats for Detecting Glucose in Urine.$h[electronic resource]
260 $c2023
300 $a2209–2218
520 $a: We report on a flexible, bifunctional platform made with solution-blow spinning fiber mats of polylactic acid (PLA) and polyethylene glycol (PEG). The PLA/PEG mats were designated bifunctional because they were used as a substrate for screenprinted carbon electrodes (SPCEs) and as a matrix to attach glucose oxidase (GOx)covalently. By attaching GOx only on the fiber mats, and not on the SPCE, the detectionof hydrogen peroxide generated from glucose oxidation by the enzyme was efficient,especially with Prussian blue (PB) nanoparticles electrodeposited on the SPCE surface.The bifunctional device detected hydrogen peroxide (H2O2) in synthetic and humanurine at a low applied potential (0 V vs Ag/AgCl) in the range from 1.0 to 6.0 mM, witha detection limit of 0.197 mM, being also interference-free. The biosensor whose cost is<US$ 0.25 per unit (estimated from the price of the materials used) had performance comparable to the gold standard method while measuring glucose in human urine samples, in addition to exhibiting a rapid response and long lifetime. The design of the bifunctional device is generic and may be extended to other biosensors for on-site monitoring as well as for wearable devices and inmonitoring the environment and water in varied resources
653 $aBiodegradable and biocompatible mat
653 $aGlucose electrochemical biosensor
653 $aPolylactic acid (PLA)
653 $aSolution-blow spinning
653 $aUrine non-invasive sample
700 1 $aPASCHOALIN, R. T.
700 1 $aBILLATO, S.
700 1 $aSORIGOTTI, A. R.
700 1 $aFARINAS, C. S.
700 1 $aMATTOSO, L. H. C.
700 1 $aMACHADO, S. A. S.
700 1 $aOLIVEIRA JR., O. N.
700 1 $aRAYMUNDO-PEREIRA, P. A.
773 $tACS Sustainable Chemistry & Engineering$gv. 11, 2023.
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