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Registro Completo |
Biblioteca(s): |
Ebooks. |
Data corrente: |
01/02/2013 |
Data da última atualização: |
01/02/2013 |
Autoria: |
SWERDLOW, N. R. |
Afiliação: |
Neal R. Swerdlow. |
Título: |
Behavioral Neurobiology of Schizophrenia and Its Treatment. |
Ano de publicação: |
2010 |
Fonte/Imprenta: |
Springer eBooks. |
Volume: |
4 |
Páginas: |
XVIII, 666 p. |
Descrição Física: |
digital. |
Série: |
Current Topics in Behavioral Neurosciences, |
ISBN: |
9783642137174 |
DOI: |
10.1007/978-3-642-13717-4 |
Idioma: |
Inglês |
Conteúdo: |
Part I. Function, Outcome and Treatment in Schizophrenia -- Part II. Experimental Measures of Brain Function and Dysfunction in Schizophrenia -- Part III. Neural Substrates of Schizophrenia -- Part IV. Genetic and Molecular Substrates of Schizophrenia.Schizophrenia research is in a dynamic state; this text gives a foothold for where we stand today, and a map for where our field may move tomorrow. Chapters on treatment describe major changes in clinical and neural targets, and new technologies for drug delivery, even as we struggle to address adverse effects of old treatments. The text next reviews advances in the experimental analysis of the schizophrenias. Where we once faced a paucity of biological signals, our field now sees an expanding list of clear neural abnormalities, and chapters focus on those in circuitry connecting prefrontal cortex, thalamus and mesial temporal lobes. The rapid evolution of schizophrenia genetics is described: older strategies for finding disorder genes, jettisoned in favor of studies of aberrant copy number variants, rare mutations or DNA methylation, and of molecular signaling pathways that trigger downstream disturbances in critical brain circuits. With what we now know about the complex biology of the schizophrenias, a key question becomes whether we can manipulate this biology in a way that fundamentally changes the course of this disorder. This text provides a context for students, investigators and clinicians to understand this stage in our evolving field, and to look ahead to the future of schizophrenia research. MenosPart I. Function, Outcome and Treatment in Schizophrenia -- Part II. Experimental Measures of Brain Function and Dysfunction in Schizophrenia -- Part III. Neural Substrates of Schizophrenia -- Part IV. Genetic and Molecular Substrates of Schizophrenia.Schizophrenia research is in a dynamic state; this text gives a foothold for where we stand today, and a map for where our field may move tomorrow. Chapters on treatment describe major changes in clinical and neural targets, and new technologies for drug delivery, even as we struggle to address adverse effects of old treatments. The text next reviews advances in the experimental analysis of the schizophrenias. Where we once faced a paucity of biological signals, our field now sees an expanding list of clear neural abnormalities, and chapters focus on those in circuitry connecting prefrontal cortex, thalamus and mesial temporal lobes. The rapid evolution of schizophrenia genetics is described: older strategies for finding disorder genes, jettisoned in favor of studies of aberrant copy number variants, rare mutations or DNA methylation, and of molecular signaling pathways that trigger downstream disturbances in critical brain circuits. With what we now know about the complex biology of the schizophrenias, a key question becomes whether we can manipulate this biology in a way that fundamentally changes the course of this disorder. This text provides a context for students, investigators and clinicians to understand this stage in o... Mostrar Tudo |
Palavras-Chave: |
Biomedicine; Molecular Medicine; Neurochemistry; Neurology; Neurosciences; Psychiatry; Psychopharmacology. |
Thesaurus Nal: |
medicine. |
Categoria do assunto: |
-- |
URL: |
https://dx.doi.org/10.1007/978-3-642-13717-4
|
Marc: |
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42. | | CURCIO, G. R.; BONNET, A.; CAVIGLIONE, J. H. Levantamento de solos no Subplanalto de Cascavel - PronaSolos, PR. Pesquisa Florestal Brasileira, Colombo, v. 39, (nesp), e201902043, 2019. p. 666. Edição especial dos resumos do IUFRO World Congress, 25., 2019, Curitiba.Tipo: Resumo em Anais de Congresso |
Biblioteca(s): Embrapa Florestas. |
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46. | | NEVES, M. B. das; LIMA, C. A. B. de; MARTINS, J. F. da S.; GRÜTZMACHER, A. D.; BÜTTOW, G. T.; SILVA, L. F. da; STRIEDER, G. M. Influência do diâmetro de amostras de solo e raízes na avaliação da infestação larval de Oryzophagus oryzae em cultivares de arroz. In: CONGRESSO BRASILEIRO DE ARROZ IRRIGADO, 7., 2011, Balneário Camboriú. Racionalizando recursos e ampliando oportunidades: anais. Itajaí: Epagri, 2011. v. 1. P. 666-669.Tipo: Resumo em Anais de Congresso |
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49. | | COPPENS d'EECKENBRUGGE, G.; CABRAL, J. R. S.; MATOS, A. P. de; CARLIER, J.; LEITÃO, J.; DUVAL, M. F.; NOYER, J. L.; FERREIRA, F. R.; LEAL, F.; MAGGIONI, L.; SUÁREZ, Z. Main results from the EU-funded project "Evaluation and utilization of pineapple genetic resources from Amazon to breed resistant varieties". Acta Horticulturae, n. 666, p. 77-82, Jan. 2005.Biblioteca(s): Embrapa Recursos Genéticos e Biotecnologia. |
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52. | | ALMEIDA, A. M. R.; VLIET, H. van der; KITAJIMA, E. W.; PIUGA, F. F.; MARIN, S. R. R.; VALENTININ, N.; BINNECK, E.; NEPOMUCENO, A. L.; BENATO, L. C. Necrose da haste da soja associada a um carlavirus. Fitopatologia Brasileira, Brasília, v. 27, p. S199, ago. 2002. Suplemento. Resumo 666. Edição do XXXV Congresso Brasileiro de Fitopatologia, Recife, PE, ago. 2002.Tipo: Resumo em Anais de Congresso |
Biblioteca(s): Embrapa Soja. |
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53. | | COSTA, E. V.; VENTURA. H. T.; FIGUEIREDO, E. A. P. de; SILVA, F. F.; GLÓRIA, L. S.; GODINHO, R. M.; RESENDE, M. D. V. de; LOPES, P. S. Multi-trait and repeatability models for genetic evaluation of litter traits in pigs considering different farrowings. Revista Brasileira de Saúde e Produção Animal, Salvador, v. 17, n. 4, p. 666-676, 2016.Tipo: Artigo em Periódico Indexado | Circulação/Nível: B - 2 |
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54. | | CARATTI, F. C.; LAMEGO, F. P.; SILVA, J. D. G.; GARCIA, J. R. Partitioning of competition for resources between soybean and corn as competitor plant. Planta Daninha, Viçosa, MG, v. 34, n. 4, p. 657-666, out./dez. 2016.Tipo: Artigo em Periódico Indexado | Circulação/Nível: B - 1 |
Biblioteca(s): Embrapa Pecuária Sul. |
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Biblioteca(s): Embrapa Semiárido. |
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56. | | SILVA, T. A. L.; FONTENELE, R. S.; FARIA, J. C.; ARAGAO, F. J. L.; RIBEIRO, S. da G. Perspectiva para o uso no Brasil de feijão geneticamente modificado, baseada na diversidade genética de Bean golden mosaic vírus. In: ENCONTRO DO TALENTO ESTUDANTIL DA EMBRAPA RECURSOS GENÉTICOS E BIOTECNOLOGIA, 15., 2010, Brasília, DF. Anais: resumos dos trabalhos. Brasília, DF: Embrapa Recursos Genéticos e Biotecnologia, 2010. Resumo 030.Tipo: Resumo em Anais de Congresso |
Biblioteca(s): Embrapa Recursos Genéticos e Biotecnologia. |
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59. | | PARRON, L. M.; GARCIA, J. R.; CAMPANHA, M. M.; MAIA, C. M. B. de F.; QUEIROZ, D. L. de; PEIXOTO, R. T. dos G.; FRITZSONS, E.; WREGE, M. S. Serviços ecossistêmicos e eucalipto. In: OLIVEIRA, E. B. de; PINTO JUNIOR, J. E. (Ed.). O eucalipto e a Embrapa: quatro décadas de pesquisa e desenvolvimento. Brasília, DF: Embrapa, 2021. cap. 14. p. 611-666. Incluí apêndices.Tipo: Capítulo em Livro Técnico-Científico |
Biblioteca(s): Embrapa Florestas; Embrapa Milho e Sorgo; Embrapa Solos. |
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60. | | NEPSTAD, D. C.; CARVALHO, C. R. de; DAVIDSON, E. A.; JIPP, P. H.; LEFEBIRE, P. A.; NEGREIROS, G. H.; SILVA, E. D. da; STONE, T. A.; TRUMBORE, S. E. The role of deep roots in the hydrological and carbon cycles of Amazonian forests and pastures. Nature, v. 372, n. 6507, p.666-669, Dec. 1994.Biblioteca(s): Embrapa Amazônia Oriental. |
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