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Registro Completo |
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Biblioteca(s): |
Embrapa Agroindústria Tropical; Embrapa Semiárido. |
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Data corrente: |
03/01/2020 |
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Data da última atualização: |
03/07/2020 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
GUEDES, J. A. C.; ALVES FILHO, E. DE G.; SILVA, M. F. S.; RODRIGUES, T. H. S.; RAMIRES, C. M. C.; LIMA, M. A. C. de; SILVA, G. S. DA; PESSOA, C. DO Ó; CANUTO, K. M.; BRITO, E. S. de; ALVES, R. E.; NASCIMENTO, R. F. DO; ZOCOLO, G. J. |
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Afiliação: |
JHONYSON ARRUDA CARVALHO GUEDES, Departamento de Química Analítica e Físico-Química, Universidade Federal do Ceará; ELENILSON DE GODOY ALVES FILHO, Embrapa Agroindústria Tropical; MARIA FRANCILENE SOUZA SILVA, Departamento de Fisiologia e Farmacologia, Universidade Federal do Ceará; TIGRESSA HELENA SOARES RODRIGUES, Universidade Estadual do Vale do Acaraú, Sobral; CHRISTIANE MENDES CASSIMIRO RAMIRES, Empresa Estadual de Pesquisa Agropecuária da Paraíba (EMEPA); MARIA AUXILIADORA COELHO DE LIMA, CPATSA; GISELE SILVESTRE DA SILVA, Embrapa Agroindústria Tropical; CLAUDIA DO Ó PESSOA, Departamento de Fisiologia e Farmacologia, Universidade Federal do Ceará; KIRLEY MARQUES CANUTO, CNPAT; EDY SOUSA DE BRITO, CNPAT; RICARDO ELESBAO ALVES, CNAT; RONALDO FERREIRA DO NASCIMENTO, Departamento de Química Analítica e Físico-Química, Universidade Federal do Ceará; GUILHERME JULIAO ZOCOLO, CNPAT. |
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Título: |
GC-MS-based metabolomic profiles combined with chemometric tools and cytotoxic activities of non-polar leaf extracts of Spondias mombin L. and Spondias tuberosa Arr. Cam. |
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Ano de publicação: |
2020 |
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Fonte/Imprenta: |
Journal of the Brazilian Chemical Society, Campinas, v. 31, n. 2, p. 331-340, 2020. |
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DOI: |
https://doi.org/10.21577/0103-5053.20190185 |
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Idioma: |
Inglês |
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Conteúdo: |
Agroindustrial residues, such as leaves of fruit plants, can be sources of bioactive molecules, thus adding value to co-products that are rarely explored in agroindustry. In this context, this study aimed to look into the phytochemical profiles in detail and to explore the antitumor potential of S. tuberosa and S. mombin leaves. We observed that, S. tuberosa leaf extract was cytotoxic in both tumor and healthy cells. S. mombin extracts selectively inhibited cell proliferation in the tumor cell line for prostate cancer (PC3) and did not significantly affect healthy cells. The metabolic profiles of the extracts were evaluated by gas chromatography coupled with mass spectrometry and twenty-three metabolites were identified. The correlation of metabolic profiles with cytotoxic tests indicated possible chemical markers that may be responsible for the inhibition of cell proliferation. This study revealed that the unexplored co-products in agroindustry may have great therapeutic potential, and therefore should be screened for biologically active compounds |
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Palavras-Chave: |
Agroindustria; Co-produto; Metabolômica; Residuo agroindustrial. |
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Thesagro: |
Cromatografia; Spondias Mombin; Umbu. |
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Thesaurus Nal: |
Chromatography; Metabolomics; Spondias; Yellow mombins. |
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Categoria do assunto: |
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F Plantas e Produtos de Origem Vegetal |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/208109/1/ART19066.pdf
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/210746/1/Based-Metabolomic-Profiles-Combined-with-Chemometric-Tools.pdf
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Marc: |
LEADER 02354naa a2200409 a 4500
001 2118083
005 2020-07-03
008 2020 bl uuuu u00u1 u #d
024 7 $ahttps://doi.org/10.21577/0103-5053.20190185$2DOI
100 1 $aGUEDES, J. A. C.
245 $aGC-MS-based metabolomic profiles combined with chemometric tools and cytotoxic activities of non-polar leaf extracts of Spondias mombin L. and Spondias tuberosa Arr. Cam.$h[electronic resource]
260 $c2020
520 $aAgroindustrial residues, such as leaves of fruit plants, can be sources of bioactive molecules, thus adding value to co-products that are rarely explored in agroindustry. In this context, this study aimed to look into the phytochemical profiles in detail and to explore the antitumor potential of S. tuberosa and S. mombin leaves. We observed that, S. tuberosa leaf extract was cytotoxic in both tumor and healthy cells. S. mombin extracts selectively inhibited cell proliferation in the tumor cell line for prostate cancer (PC3) and did not significantly affect healthy cells. The metabolic profiles of the extracts were evaluated by gas chromatography coupled with mass spectrometry and twenty-three metabolites were identified. The correlation of metabolic profiles with cytotoxic tests indicated possible chemical markers that may be responsible for the inhibition of cell proliferation. This study revealed that the unexplored co-products in agroindustry may have great therapeutic potential, and therefore should be screened for biologically active compounds
650 $aChromatography
650 $aMetabolomics
650 $aSpondias
650 $aYellow mombins
650 $aCromatografia
650 $aSpondias Mombin
650 $aUmbu
653 $aAgroindustria
653 $aCo-produto
653 $aMetabolômica
653 $aResiduo agroindustrial
700 1 $aALVES FILHO, E. DE G.
700 1 $aSILVA, M. F. S.
700 1 $aRODRIGUES, T. H. S.
700 1 $aRAMIRES, C. M. C.
700 1 $aLIMA, M. A. C. de
700 1 $aSILVA, G. S. DA
700 1 $aPESSOA, C. DO Ó
700 1 $aCANUTO, K. M.
700 1 $aBRITO, E. S. de
700 1 $aALVES, R. E.
700 1 $aNASCIMENTO, R. F. DO
700 1 $aZOCOLO, G. J.
773 $tJournal of the Brazilian Chemical Society, Campinas$gv. 31, n. 2, p. 331-340, 2020.
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Registro original: |
Embrapa Agroindústria Tropical (CNPAT) |
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Biblioteca |
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Registro |
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Registro Completo
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Biblioteca(s): |
Embrapa Meio Ambiente. |
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Data corrente: |
14/11/2014 |
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Data da última atualização: |
04/01/2023 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
B - 1 |
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Autoria: |
PARAIBA, L. C.; PAZIANOTTO, R. A. A.; LUIZ, A. J. B.; MAIA, A. de H. N.; JONSSON, C. M. |
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Afiliação: |
LOURIVAL COSTA PARAIBA, CNPMA; RICARDO ANTONIO ALMEIDA PAZIANOTTO, CNPMA; ALFREDO JOSE BARRETO LUIZ, CNPMA; ALINE DE HOLANDA NUNES MAIA, CNPMA; CLAUDIO MARTIN JONSSON, CNPMA. |
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Título: |
A mathematical model to estimate the volume of grey water of pesticide mixtures. |
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Ano de publicação: |
2014 |
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Fonte/Imprenta: |
Spanish Journal of Agricultural Research, Madrid, v. 12, n. 2, p. 509-518, 2014. |
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Idioma: |
Inglês |
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Conteúdo: |
The usual method to calculate grey water footprint does not take into account the volume of water required to dilute concentrations of pesticide mixtures in freshwater and it also depends on maximum concentration limit acceptable in water. We propose a model to estimate the grey water footprint of crops by calculating the volume of water necessary to dilute pesticide mixtures reaching freshwaters. The model requires short-term toxicity data from aquatic organisms based on EC50 values, soil pesticide half-life and soil sorption coefficient values, and does not require maximum concentration limit acceptable in water. The lixiviation rate and runoff rate of each pesticide was estimated by attenuation factor and by Soilfug model, respectively. The usefulness of the proposed model was illustrated by estimating the volume of grey water required to dilute the 17 most widely used herbicides in sugarcane crops of Brazil. The grey water footprint corresponding to the recommended agronomic dose for each herbicide varied between 4.20×106 m3 yr-1 and 1.20×1012 m3 yr-1 and the grey water footprint of the mixture of herbicides was 2.36×1012 m3 yr-1 in a cultivated area of 8.4×106 ha. These results establish the ranking position of each herbicide in the composition of the grey water footprint of mixture of herbicides. The rank of each herbicide could be used to create a label to be placed on the package of the pesticide, thus informing farmers about the volume of grey water per hectare due to the use of this herbicide. MenosThe usual method to calculate grey water footprint does not take into account the volume of water required to dilute concentrations of pesticide mixtures in freshwater and it also depends on maximum concentration limit acceptable in water. We propose a model to estimate the grey water footprint of crops by calculating the volume of water necessary to dilute pesticide mixtures reaching freshwaters. The model requires short-term toxicity data from aquatic organisms based on EC50 values, soil pesticide half-life and soil sorption coefficient values, and does not require maximum concentration limit acceptable in water. The lixiviation rate and runoff rate of each pesticide was estimated by attenuation factor and by Soilfug model, respectively. The usefulness of the proposed model was illustrated by estimating the volume of grey water required to dilute the 17 most widely used herbicides in sugarcane crops of Brazil. The grey water footprint corresponding to the recommended agronomic dose for each herbicide varied between 4.20×106 m3 yr-1 and 1.20×1012 m3 yr-1 and the grey water footprint of the mixture of herbicides was 2.36×1012 m3 yr-1 in a cultivated area of 8.4×106 ha. These results establish the ranking position of each herbicide in the composition of the grey water footprint of mixture of herbicides. The rank of each herbicide could be used to create a label to be placed on the package of the pesticide, thus informing farmers about the volume of grey water per hectare due ... Mostrar Tudo |
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Palavras-Chave: |
Cana-de-açúcar; Pesticide management; Water quality objective. |
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Thesagro: |
Agrotóxico; Herbicida; Modelo matemático; Qualidade da água. |
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Thesaurus NAL: |
Environmental impact; Herbicides; Mathematical models; Sugarcane; Water footprint; Water quality. |
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Categoria do assunto: |
P Recursos Naturais, Ciências Ambientais e da Terra |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/111687/1/2014AP013.pdf
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Marc: |
LEADER 02495naa a2200325 a 4500
001 2000149
005 2023-01-04
008 2014 bl uuuu u00u1 u #d
100 1 $aPARAIBA, L. C.
245 $aA mathematical model to estimate the volume of grey water of pesticide mixtures.$h[electronic resource]
260 $c2014
520 $aThe usual method to calculate grey water footprint does not take into account the volume of water required to dilute concentrations of pesticide mixtures in freshwater and it also depends on maximum concentration limit acceptable in water. We propose a model to estimate the grey water footprint of crops by calculating the volume of water necessary to dilute pesticide mixtures reaching freshwaters. The model requires short-term toxicity data from aquatic organisms based on EC50 values, soil pesticide half-life and soil sorption coefficient values, and does not require maximum concentration limit acceptable in water. The lixiviation rate and runoff rate of each pesticide was estimated by attenuation factor and by Soilfug model, respectively. The usefulness of the proposed model was illustrated by estimating the volume of grey water required to dilute the 17 most widely used herbicides in sugarcane crops of Brazil. The grey water footprint corresponding to the recommended agronomic dose for each herbicide varied between 4.20×106 m3 yr-1 and 1.20×1012 m3 yr-1 and the grey water footprint of the mixture of herbicides was 2.36×1012 m3 yr-1 in a cultivated area of 8.4×106 ha. These results establish the ranking position of each herbicide in the composition of the grey water footprint of mixture of herbicides. The rank of each herbicide could be used to create a label to be placed on the package of the pesticide, thus informing farmers about the volume of grey water per hectare due to the use of this herbicide.
650 $aEnvironmental impact
650 $aHerbicides
650 $aMathematical models
650 $aSugarcane
650 $aWater footprint
650 $aWater quality
650 $aAgrotóxico
650 $aHerbicida
650 $aModelo matemático
650 $aQualidade da água
653 $aCana-de-açúcar
653 $aPesticide management
653 $aWater quality objective
700 1 $aPAZIANOTTO, R. A. A.
700 1 $aLUIZ, A. J. B.
700 1 $aMAIA, A. de H. N.
700 1 $aJONSSON, C. M.
773 $tSpanish Journal of Agricultural Research, Madrid$gv. 12, n. 2, p. 509-518, 2014.
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Embrapa Meio Ambiente (CNPMA) |
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