Data/hora: 05/06/2024 13:11:11

Biblioteca(s): | Embrapa Pantanal.
Data corrente: | 01/10/1997
Data da última atualização: | 05/04/2017
Autoria: | ZWEYGARTH, E.; KAMINSKY, R.; MOLOO, S. K.
Título: | Evaluation of a shorth-term in vitro growth-inhibition test to determine susceptibility of Trypanosoma vivax stocks to various trypanocides.
Ano de publicação: | 1994
Fonte/Imprenta: | Onderstepoort Journal of Veterinary Research, v.61, n.2, p.189-191, 1994.
Idioma: | Inglês
Conteúdo: | Two Trypanosoma vivax stocks were initiated in culture with tsetse or culture-derived metacyclics. They were propagated axenically as bloodstream trypomastigotes at 35C in 4% CO2 in air. Populations of trypanosomes were incubated with various concentrations of antitrypanosomal compoun ds, namely diminazene aceturate, quinapyramine sulphate, DL-difluoromethylornithine, isometamidium chloride, suramin and mel Cy. Growth was monitores after 24 h of incubation and the growth inhibition was calculated. All six drugs tested showed little effect upon the growth of the parasite populations. These results indicate that 24-h growth-inhibition test was not suitable for determining the drug suceptibility of T. vivax stocks in vitro. Neither did the results correlate with those obtained with susceptible or resistant stocks of T. brucei, T.b. evansi or T. simiae described in the literature, or with the results of these two T. vivax stocks tested in cattle.
Thesagro: | Trypanosoma Vivax.
Categoria do assunto: | --
Registro original: | Embrapa Pantanal (CPAP)
Exemplares: | CPAP - (35034-1) - ADD - SP - PP - SP15396 -  - 15396 - DIS