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 | Acesso ao texto completo restrito à biblioteca da Embrapa Gado de Leite. Para informações adicionais entre em contato com cnpgl.biblioteca@embrapa.br. |
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Registro Completo |
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Biblioteca(s): |
Embrapa Gado de Leite. |
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Data corrente: |
10/12/2021 |
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Data da última atualização: |
10/05/2022 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
ZANETTE, R. de S. S.; FAYER, L.; OLIVEIRA, E. R. de; ALMEIDA, C. G.; OLIVEIRA, C. R. de; OLIVEIRA, L. F. C. de; MARANDUBA, C. M. C.; ALVARENGA, E. C.; BRANDAO, H. de M.; MUNK, M. |
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Afiliação: |
RAFAELLA DE S. S. ZANETTE, Universidade Federal de Juiz de Fora; LEONARA FAYER, Universidade Federal de Juiz de Fora; EDUARDA R. DE OLIVEIRA, Universidade Federal de Juiz de Fora; CAMILA G. ALMEIDA; CAUE RIBEIRO DE OLIVEIRA, CNPDIA; LUIZ F. C. DE OLIVEIRA, Universidade Federal de Juiz de Fora; CARLOS M. C. MARANDUBA, Universidade Federal de Juiz de Fora; ERIKA C. ALVARENGA, Universidade Federal de São João del-Rei; HUMBERTO DE MELLO BRANDAO, CNPGL; MICHELE MUNK, Universidade Federal de Juiz de Fora. |
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Título: |
Cytocompatibility and osteogenic differentiation of stem cells from human exfoliated deciduous teeth with cotton cellulose nanofibers for tissue engineering and regenerative medicine. |
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Ano de publicação: |
2022 |
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Fonte/Imprenta: |
Journal of Biomaterials Science, Polymer Edition, v. 33, n. 5, p. 627-650, 2022. |
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DOI: |
https://doi.org/10.1080/09205063.2021.2008787 |
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Idioma: |
Inglês |
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Notas: |
Publicado online em 24 nov. 2021. |
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Conteúdo: |
Cellulose nanofibers (CNFs) are natural polymers with physical-chemical properties that make them very attractive for modulating stem cell differentiation, a crucial step in tissue engineering and regenerative medicine. Although cellulose is cytocompatible, when materials are in nanoscale, they become more reactive, needing to evaluate its potential toxic effect to ensure safe application. This study aimed to investigate the cytocompatibility of cotton CNF and its differentiation capacity induction on stem cells from human exfoliated deciduous teeth. First, the cotton CNF was characterized. Then, the cytocompatibility and the osteogenic differentiation induced by cotton CNF were examined. The results revealed that cotton CNFs have about 6?18 nm diameters, and the zeta potential was 10 mV. Despite gene expression alteration, the cotton CNF shows good cytocompatibility. The cotton CNF induced an increase in phosphatase alkaline activity and extracellular matrix mineralization. The results indicate that cotton CNF has good cytocompatibility and can promote cell differentiation without using chemical inducers, showing great potential as a new differentiation inductor for tissue engineering and regenerative medicine applications. |
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Palavras-Chave: |
Diferenciação osteogênica; Nanomaterial; Nanotoxicidade; Terapia celular. |
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Thesagro: |
Algodão; Célula; Celulose. |
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Categoria do assunto: |
F Plantas e Produtos de Origem Vegetal |
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Marc: |
LEADER 02382naa a2200337 a 4500
001 2137515
005 2022-05-10
008 2022 bl uuuu u00u1 u #d
024 7 $ahttps://doi.org/10.1080/09205063.2021.2008787$2DOI
100 1 $aZANETTE, R. de S. S.
245 $aCytocompatibility and osteogenic differentiation of stem cells from human exfoliated deciduous teeth with cotton cellulose nanofibers for tissue engineering and regenerative medicine.$h[electronic resource]
260 $c2022
500 $aPublicado online em 24 nov. 2021.
520 $aCellulose nanofibers (CNFs) are natural polymers with physical-chemical properties that make them very attractive for modulating stem cell differentiation, a crucial step in tissue engineering and regenerative medicine. Although cellulose is cytocompatible, when materials are in nanoscale, they become more reactive, needing to evaluate its potential toxic effect to ensure safe application. This study aimed to investigate the cytocompatibility of cotton CNF and its differentiation capacity induction on stem cells from human exfoliated deciduous teeth. First, the cotton CNF was characterized. Then, the cytocompatibility and the osteogenic differentiation induced by cotton CNF were examined. The results revealed that cotton CNFs have about 6?18 nm diameters, and the zeta potential was 10 mV. Despite gene expression alteration, the cotton CNF shows good cytocompatibility. The cotton CNF induced an increase in phosphatase alkaline activity and extracellular matrix mineralization. The results indicate that cotton CNF has good cytocompatibility and can promote cell differentiation without using chemical inducers, showing great potential as a new differentiation inductor for tissue engineering and regenerative medicine applications.
650 $aAlgodão
650 $aCélula
650 $aCelulose
653 $aDiferenciação osteogênica
653 $aNanomaterial
653 $aNanotoxicidade
653 $aTerapia celular
700 1 $aFAYER, L.
700 1 $aOLIVEIRA, E. R. de
700 1 $aALMEIDA, C. G.
700 1 $aOLIVEIRA, C. R. de
700 1 $aOLIVEIRA, L. F. C. de
700 1 $aMARANDUBA, C. M. C.
700 1 $aALVARENGA, E. C.
700 1 $aBRANDAO, H. de M.
700 1 $aMUNK, M.
773 $tJournal of Biomaterials Science, Polymer Edition$gv. 33, n. 5, p. 627-650, 2022.
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Registro original: |
Embrapa Gado de Leite (CNPGL) |
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| Acesso ao texto completo restrito à biblioteca da Embrapa Arroz e Feijão. Para informações adicionais entre em contato com cnpaf.biblioteca@embrapa.br. |
Registro Completo
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Biblioteca(s): |
Embrapa Arroz e Feijão. |
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Data corrente: |
04/08/2015 |
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Data da última atualização: |
27/04/2020 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
A - 2 |
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Autoria: |
CARVALHO, J. C. B.; SOUSA, K. C. I.; BRITO, D. C.; CHAIBUB, A. A.; LUZINI, A. P.; CORTES, M. V. C. B.; FILIPPI, M. C. C.; KATO, L.; VAZ, B. G.; COSTA, H. B.; ROMÃO, W.; ARAÚJO, L. G. |
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Afiliação: |
JACQUELINE C. B. CARVALHO, UFG; KELLEN C. I. SOUSA, UFG; DENISE C. BRITO, UFG; AMANDA A. CHAIBUB, UFG; ALINE P. LUZINI, UFG; MARCIO VINICIUS DE C BARROS CORTES, CNPAF; MARTA CRISTINA CORSI DE FILIPPI, CNPAF; LUCILIA KATO, UFG; BONIEK G. VAZ, UFG; HELBER B. COSTA, UFES; WANDERSON ROMÃO, UFES; LEILA GARCÊS DE ARAUJO, UFG. |
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Título: |
Biocontrol potential of Waitea circinata, an orchid mycorrhizal fungus, against the rice blast fungus. |
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Ano de publicação: |
2015 |
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Fonte/Imprenta: |
Tropical Plant Pathology, v. 40, n. 3, p. 151-159, June 2015. |
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DOI: |
10.1007/s40858-015-0042-8 |
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Idioma: |
Inglês |
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Conteúdo: |
Rice blast (Magnaporthe oryzae) occurs in rice producing areas worldwide. Microorganisms are capable of producing secondary metabolites that can control the pathogen. The present study aimed to identify the class of the secondary metabolites produced by the mycorrhizal fungus Waitea circinata obtained from a Cerrado orchid and to assess the in vitro and in vivo antagonism of the extracts against M. oryzae. Three mycorrhizal extracts (crude, mycelial and lyophilized) were obtained. In the in vitro antagonism assay, W. circinata produced the largest inhibition zone. The crude extract reduced the mycelial growth of the pathogen by 75 %, inhibited the formation of appressoria by 100 % and reduced the AUDPC by 25 % compared to the control. Analysis of the crude extract by electro spray ionization Fourier transform ion cyclotron resonance mass spectrometry revealed the presence of benzophenones. The results suggest that W. circinata extract has the potential for rice blast control. |
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Palavras-Chave: |
Bioactive product. |
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Thesagro: |
Arroz; Brusone; Doença de planta; Fungo; Micorriza; Oryza sativa. |
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Thesaurus NAL: |
Mycorrhizal fungi. |
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Categoria do assunto: |
H Saúde e Patologia |
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Marc: |
LEADER 01985naa a2200361 a 4500
001 2021332
005 2020-04-27
008 2015 bl uuuu u00u1 u #d
024 7 $a10.1007/s40858-015-0042-8$2DOI
100 1 $aCARVALHO, J. C. B.
245 $aBiocontrol potential of Waitea circinata, an orchid mycorrhizal fungus, against the rice blast fungus.
260 $c2015
520 $aRice blast (Magnaporthe oryzae) occurs in rice producing areas worldwide. Microorganisms are capable of producing secondary metabolites that can control the pathogen. The present study aimed to identify the class of the secondary metabolites produced by the mycorrhizal fungus Waitea circinata obtained from a Cerrado orchid and to assess the in vitro and in vivo antagonism of the extracts against M. oryzae. Three mycorrhizal extracts (crude, mycelial and lyophilized) were obtained. In the in vitro antagonism assay, W. circinata produced the largest inhibition zone. The crude extract reduced the mycelial growth of the pathogen by 75 %, inhibited the formation of appressoria by 100 % and reduced the AUDPC by 25 % compared to the control. Analysis of the crude extract by electro spray ionization Fourier transform ion cyclotron resonance mass spectrometry revealed the presence of benzophenones. The results suggest that W. circinata extract has the potential for rice blast control.
650 $aMycorrhizal fungi
650 $aArroz
650 $aBrusone
650 $aDoença de planta
650 $aFungo
650 $aMicorriza
650 $aOryza sativa
653 $aBioactive product
700 1 $aSOUSA, K. C. I.
700 1 $aBRITO, D. C.
700 1 $aCHAIBUB, A. A.
700 1 $aLUZINI, A. P.
700 1 $aCORTES, M. V. C. B.
700 1 $aFILIPPI, M. C. C.
700 1 $aKATO, L.
700 1 $aVAZ, B. G.
700 1 $aCOSTA, H. B.
700 1 $aROMÃO, W.
700 1 $aARAÚJO, L. G.
773 $tTropical Plant Pathology$gv. 40, n. 3, p. 151-159, June 2015.
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Embrapa Arroz e Feijão (CNPAF) |
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