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Registro Completo |
Biblioteca(s): |
Embrapa Florestas; Embrapa Mandioca e Fruticultura. |
Data corrente: |
28/12/2016 |
Data da última atualização: |
03/01/2018 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Autoria: |
AZEVEDO, C. F.; RESENDE, M. D. V. de; SILVA, F. F.; VIANA, J. M. S.; VALENTE, M. S. F.; RESENDE JUNIOR, M. F. R.; OLIVEIRA, E. J. de. |
Afiliação: |
C. F. Azevedo, Departamento de Estatística, Universidade Federal de Viçosa; MARCOS DEON VILELA DE RESENDE, CNPF; F. F. Silva, Departamento de Zootecnia, Universidade Federal de Viçosa; J. M. S. Viana, Departamento de Biologia Geral, Universidade Federal de Viçosa; M. S. F. Valente, Departamento de Biologia Geral, Universidade Federal de Viçosa; M. F. R. Resende Junior, RAPID Genomics, Florida; EDER JORGE DE OLIVEIRA, CNPMF. |
Título: |
New accuracy estimators for genomic selection with application in a cassava (Manihot esculenta) breeding program. |
Ano de publicação: |
2016 |
Fonte/Imprenta: |
Genetics and Molecular Research, v. 15, n. 4, gmr.15048838, Oct. 2016. |
DOI: |
10.4238/gmr.15048838 |
Idioma: |
Inglês |
Conteúdo: |
ABSTRACT. Genomic selection is the main force driving applied breeding programs and accuracy is the main measure for evaluating its efficiency. The traditional estimator (TE) of experimental accuracy is not fully adequate. This study proposes and evaluates the performance and efficiency of two new accuracy estimators, called regularized estimator (RE) and hybrid estimator (HE), which were applied to a practical cassava breeding program and also to simulated data. The simulation study considered two individual narrow sense heritability levels and two genetic architectures for traits. TE, RE, and HE were compared under four validation procedures: without validation (WV), independent validation, ten-fold validation through jacknife allowing different markers, and with the same markers selected in each cycle. RE presented accuracies closer to the parametric ones and less biased and more precise ones than TE. HE proved to be very effective in the WV procedure. The estimators were applied to five traits evaluated in a cassava experiment, including 358 clones genotyped for 390 SNPs. Accuracies ranged from 0.67 to 1.12 with TE and from 0.22 to 0.51 with RE. These results indicated that TE overestimated the accuracy and led to one accuracy estimate (1.12) higher than one, which is outside of the parameter space. Use of RE turned the accuracy into the parameter space. Cassava breeding programs can be more realistically implemented using the new estimators proposed in this study, providing less risky practical inferences. MenosABSTRACT. Genomic selection is the main force driving applied breeding programs and accuracy is the main measure for evaluating its efficiency. The traditional estimator (TE) of experimental accuracy is not fully adequate. This study proposes and evaluates the performance and efficiency of two new accuracy estimators, called regularized estimator (RE) and hybrid estimator (HE), which were applied to a practical cassava breeding program and also to simulated data. The simulation study considered two individual narrow sense heritability levels and two genetic architectures for traits. TE, RE, and HE were compared under four validation procedures: without validation (WV), independent validation, ten-fold validation through jacknife allowing different markers, and with the same markers selected in each cycle. RE presented accuracies closer to the parametric ones and less biased and more precise ones than TE. HE proved to be very effective in the WV procedure. The estimators were applied to five traits evaluated in a cassava experiment, including 358 clones genotyped for 390 SNPs. Accuracies ranged from 0.67 to 1.12 with TE and from 0.22 to 0.51 with RE. These results indicated that TE overestimated the accuracy and led to one accuracy estimate (1.12) higher than one, which is outside of the parameter space. Use of RE turned the accuracy into the parameter space. Cassava breeding programs can be more realistically implemented using the new estimators proposed in this study, provi... Mostrar Tudo |
Palavras-Chave: |
Accuracy estimator; Cross-validation; Genomic prediction; Mnadioca; Seleção genômica. |
Thesagro: |
Mandioca; Manihot esculenta; Melhoramento vegetal. |
Thesaurus Nal: |
Cassava; Plant breeding. |
Categoria do assunto: |
G Melhoramento Genético |
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/161813/1/2016-M.Deon-GMR-NewAccuracy.pdf
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Marc: |
LEADER 02532naa a2200325 a 4500 001 2072711 005 2018-01-03 008 2016 bl uuuu u00u1 u #d 024 7 $a10.4238/gmr.15048838$2DOI 100 1 $aAZEVEDO, C. F. 245 $aNew accuracy estimators for genomic selection with application in a cassava (Manihot esculenta) breeding program.$h[electronic resource] 260 $c2016 520 $aABSTRACT. Genomic selection is the main force driving applied breeding programs and accuracy is the main measure for evaluating its efficiency. The traditional estimator (TE) of experimental accuracy is not fully adequate. This study proposes and evaluates the performance and efficiency of two new accuracy estimators, called regularized estimator (RE) and hybrid estimator (HE), which were applied to a practical cassava breeding program and also to simulated data. The simulation study considered two individual narrow sense heritability levels and two genetic architectures for traits. TE, RE, and HE were compared under four validation procedures: without validation (WV), independent validation, ten-fold validation through jacknife allowing different markers, and with the same markers selected in each cycle. RE presented accuracies closer to the parametric ones and less biased and more precise ones than TE. HE proved to be very effective in the WV procedure. The estimators were applied to five traits evaluated in a cassava experiment, including 358 clones genotyped for 390 SNPs. Accuracies ranged from 0.67 to 1.12 with TE and from 0.22 to 0.51 with RE. These results indicated that TE overestimated the accuracy and led to one accuracy estimate (1.12) higher than one, which is outside of the parameter space. Use of RE turned the accuracy into the parameter space. Cassava breeding programs can be more realistically implemented using the new estimators proposed in this study, providing less risky practical inferences. 650 $aCassava 650 $aPlant breeding 650 $aMandioca 650 $aManihot esculenta 650 $aMelhoramento vegetal 653 $aAccuracy estimator 653 $aCross-validation 653 $aGenomic prediction 653 $aMnadioca 653 $aSeleção genômica 700 1 $aRESENDE, M. D. V. de 700 1 $aSILVA, F. F. 700 1 $aVIANA, J. M. S. 700 1 $aVALENTE, M. S. F. 700 1 $aRESENDE JUNIOR, M. F. R. 700 1 $aOLIVEIRA, E. J. de 773 $tGenetics and Molecular Research$gv. 15, n. 4, gmr.15048838, Oct. 2016.
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Registro original: |
Embrapa Florestas (CNPF) |
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Registros recuperados : 48 | |
41. | | AZEVEDO, C. F.; SILVA, F. F.; RESENDE, M. D. V. de; LOPES, M. S.; DUIJVESTEINJN, N.; GUIMARÃES, S. E. F.; LOPES, P. S.; KELLY, M. J.; VIANA, J. M. S.; KNOL, E. F. Supervised independent component analysis as an alternative method for genomic selection in pigs. Journal of Animal Breeding and Genetics, v. 131, p. 452-461, 2014.Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 2 |
Biblioteca(s): Embrapa Florestas. |
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42. | | GUIMARAES, C. T.; MAGALHAES, J. V. D.; JARDIM, S. N.; ALMEIDA, R. V.; MARON, L. G.; PAIVA, E.; ALVES, V. M. C.; VIANA, J. M. S.; HOEKENGA, O.; PARENTONI, S. N.; KOCHIAN, L. V. Validation of aluminum tolerance QTL in maize. In: CONGRESSO BRASILEIRO DE GENÉTICA, 55., 2009, Águas de Lindóia, SP. Resumos... Ribeirão Preto: Sociedade Brasileira de Genética, 2009. p. 155.Tipo: Resumo em Anais de Congresso |
Biblioteca(s): Embrapa Milho e Sorgo. |
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43. | | RAMOS, P. V. B.; SILVA, F. F. e; SILVA, L. O. C. da; SANTIAGO, G. G.; MENEZES, G. R. de O.; VIANA, J. M. S.; TORRES JUNIOR, R. A. de A.; GONDO, A.; LUIZ F. BRITO. Genomic evaluation for novel stayability traits in Nellore cattle. Reproduction in Domestic Animals, v. 55, n. 3, p. 266-273, March 2020.Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
Biblioteca(s): Embrapa Gado de Corte. |
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44. | | SILVA, F. F. e; RESENDE, M. D. V. de; ROCHA, G. S.; DUARTE, D. A. S.; LOPES, P. S.; BRUSTOLIN, O. J. B.; THUS, S.; VIANA, J. M. S.; GUIMARÃES, S. E. F. Genomic growth curves of an outbred pig population. Genetics and Molecular Biology, v. 36, n. 4, p. 520-527, 2013.Tipo: Artigo em Periódico Indexado | Circulação/Nível: B - 1 |
Biblioteca(s): Embrapa Florestas. |
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45. | | NASCIMENTO, M.; SILVA, F. F. e; RESENDE, M. D. V. de; CRUZ, C. D.; NASCIMENTO, A. C. C.; VIANA, J. M. S.; AZEVEDO, C. F.; BARROSO, L. M. A. Regularized quantile regression applied to genome-enabled prediction of quantitative traits. Genetics and Molecular Research, v. 16, n. 1, gmr16019538, 2017. 12 p.Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 2 |
Biblioteca(s): Embrapa Florestas. |
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46. | | PAIVA, J. T.; RESENDE, M. D. V. de; RESENDE, R. T.; OLIVEIRA, H. R.; SILVA, H. T.; CAETANO, G. C.; CALDERANO, A. A.; LOPES, P. S.; VIANA, J. M. S.; SILVA, F. F. A note on transgenerational epigenetics affecting egg quality traits in meat-type quail. British Poultry Science, v. 59, n. 6, p. 624-628, 2018. Short Communication.Tipo: Nota Técnica/Nota Científica |
Biblioteca(s): Embrapa Florestas. |
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47. | | OLIVEIRA, G. F.; NASCIMENTO, A. C. C.; AZEVEDO, C. F.; CELERI, M. de O.; BARROSO, L. M. A.; SANT’ANNA, I. de C.; VIANA, J. M. S.; RESENDE, M. D. V. de; NASCIMENTO, M. Population size in QTL detection using quantile regression in genome‑wide association studies. Scientific Reports, v. 13, Article 9585, 2023. 10 p.Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
Biblioteca(s): Embrapa Café. |
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48. | | FERREIRA, F. M.; CHAVES, S. F. S.; BHERING, L. L.; ALVES, R. S.; TAKAHASHI, E. K.; SOUSA, J. E.; RESENDE, M. D. V. de; LEITE, F. P.; GEZAN, S. A.; VIANA, J. M. S.; FERNANDES, S. B.; DIAS, K. O. G. A novel strategy to predict clonal composites by jointly modeling spatial variation and genetic competition. Forest Ecology and Management, v. 548, Article 121393, 2023. 10 p.Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
Biblioteca(s): Embrapa Café. |
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Registros recuperados : 48 | |
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