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 | Acesso ao texto completo restrito à biblioteca da Embrapa Milho e Sorgo. Para informações adicionais entre em contato com cnpms.biblioteca@embrapa.br. |
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Registro Completo |
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Biblioteca(s): |
Embrapa Milho e Sorgo. |
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Data corrente: |
08/11/2022 |
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Data da última atualização: |
12/12/2022 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
VEREDIANO, T. A.; SANT'ANA, C.; GRANCIERI, M.; TAKO, E.; PAES, M. C. D.; MARTIN, H. S. D. |
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Afiliação: |
THAISA AGRIZZI VEREDIANO, Universidade Federal de Viçosa; CINTIA SANT'ANA, Universidade Federal de Viçosa; MARIANA GRANCIERI, Universidade Federal de Viçosa; ELAD TAKO, Cornell University; MARIA CRISTINA DIAS PAES, CNPMS; HERCIA STAMPINI DUARTE MARTIN, Universidade Federal de Viçosa. |
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Título: |
Black corn (Zea mays L.) flour has the potential to improve the gut microbiota composition and goblet cell proliferation in mice fed a high-fat diet. |
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Ano de publicação: |
2022 |
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Fonte/Imprenta: |
Nutrition Research, v. 108, p. 60-72, 2022. |
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DOI: |
https://doi.org/10.1016/j.nutres.2022.10.005 |
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Idioma: |
Inglês |
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Conteúdo: |
High-fat diets are associated with intestinal dysbiosis and leaky gut leading to intestinal inflammation. Bioactive components, including phenolic compounds, isolated or in their original food matrix, have alleviated intestinal impairments promoted by a high-fat diet. Black corn (Zea mays L.) is a colored corn in which anthocyanins are the most abundant bioactive compound. Thus, we hypothesized that black corn flour has preventive effects on intestinal health in mice fed a high-fat diet. To study this, thirty C57BL/6 mice were randomly divided into three experimental groups receiving the following diets for eight weeks: NC: normal control (fed a normal diet); HF: high-fat (fed a high-fat diet: 60% of calories from fat); HFC: high-fat corn (fed a high-fat diet added with 20% of black corn whole flour). The cecal microbiota analyzed by 16S rRNA sequencing showed that black corn flour intake increased the relative abundance of Ruminococcus, Roseburia, and Prevotellaceae_UCG-001, and decreased Bacteroides and Faecalibaculum. No difference was observed in the cecal short-chain fatty acids and fecal pH among the experimental groups (p>0.05). Further, the consumption of black corn flour improved the cecal morphology by increasing the number of goblet cells but with no difference in the crypt depth and width. These findings suggest that black corn flour as a source of anthocyanins could have preventive effects on gut dysbiosis due to a high-fat diet. |
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Palavras-Chave: |
Barreira intestinal; Microbiota; Milho preto. |
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Thesagro: |
Ácido Graxo; Antocianina; Composto Fenólico; Dieta; Farinha; Milho. |
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Categoria do assunto: |
Q Alimentos e Nutrição Humana |
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Marc: |
LEADER 02375naa a2200301 a 4500
001 2148121
005 2022-12-12
008 2022 bl uuuu u00u1 u #d
024 7 $ahttps://doi.org/10.1016/j.nutres.2022.10.005$2DOI
100 1 $aVEREDIANO, T. A.
245 $aBlack corn (Zea mays L.) flour has the potential to improve the gut microbiota composition and goblet cell proliferation in mice fed a high-fat diet.$h[electronic resource]
260 $c2022
520 $aHigh-fat diets are associated with intestinal dysbiosis and leaky gut leading to intestinal inflammation. Bioactive components, including phenolic compounds, isolated or in their original food matrix, have alleviated intestinal impairments promoted by a high-fat diet. Black corn (Zea mays L.) is a colored corn in which anthocyanins are the most abundant bioactive compound. Thus, we hypothesized that black corn flour has preventive effects on intestinal health in mice fed a high-fat diet. To study this, thirty C57BL/6 mice were randomly divided into three experimental groups receiving the following diets for eight weeks: NC: normal control (fed a normal diet); HF: high-fat (fed a high-fat diet: 60% of calories from fat); HFC: high-fat corn (fed a high-fat diet added with 20% of black corn whole flour). The cecal microbiota analyzed by 16S rRNA sequencing showed that black corn flour intake increased the relative abundance of Ruminococcus, Roseburia, and Prevotellaceae_UCG-001, and decreased Bacteroides and Faecalibaculum. No difference was observed in the cecal short-chain fatty acids and fecal pH among the experimental groups (p>0.05). Further, the consumption of black corn flour improved the cecal morphology by increasing the number of goblet cells but with no difference in the crypt depth and width. These findings suggest that black corn flour as a source of anthocyanins could have preventive effects on gut dysbiosis due to a high-fat diet.
650 $aÁcido Graxo
650 $aAntocianina
650 $aComposto Fenólico
650 $aDieta
650 $aFarinha
650 $aMilho
653 $aBarreira intestinal
653 $aMicrobiota
653 $aMilho preto
700 1 $aSANT'ANA, C.
700 1 $aGRANCIERI, M.
700 1 $aTAKO, E.
700 1 $aPAES, M. C. D.
700 1 $aMARTIN, H. S. D.
773 $tNutrition Research$gv. 108, p. 60-72, 2022.
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Registro original: |
Embrapa Milho e Sorgo (CNPMS) |
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| Registros recuperados : 7 | |
| 5. |  | VEREDIANO, T. A.; AGARWAL, N.; MARTINO, H. S. D.; KOLBA, N.; GRANCIERI, M.; PAES, M. C. D.; TAKO, E. Effect of black corn anthocyanin-rich extract (Zea mays L.) on cecal microbial populations in vivo (Gallus gallus). Nutrients, v. 14, n. 21, 4679, 2022.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
| Biblioteca(s): Embrapa Milho e Sorgo. |
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| 6. | | FORTINI, T. V. L.; VEREDIANO, T. A.; SANT'ANA, C. T.; GRANCIERI, M.; SILVA, B. P. da; PAES, M. C. D.; MARTINO, H. Black corn (Zea mays L.) flour consumption improved the gut dysbiosis promoted by a high-fat diet on mice. In: INTERNATIONAL CONGRESS ON BIOACTIVE COMPOUNDS, 2.; INTERNATIONAL WORKSHOP ON BIOACTIVE COMPOUNDS, 3., 2022, Campinas. Personal nutrition, ageing and food science: proceedings. Campinas: Unicamp, 2022.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Milho e Sorgo. |
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| 7. | | VEREDIANO, T. A.; SANT'ANA, C. T.; GRANCIERI, M.; SÃO JOSÉ, V. P. B. de; TOLEDO, R. C. L.; PAES, M. C. D.; MARTINO, H. S. D. Black corn (Zea mays L.) whole flour improved the antioxidant capacity and prevented adipogenesis in mice fed a high-fat diet. Food & Function, v. 13, p. 5590-5601, 2022.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
| Biblioteca(s): Embrapa Milho e Sorgo. |
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| Registros recuperados : 7 | |
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| Nenhum registro encontrado para a expressão de busca informada. |
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