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Registro Completo |
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Biblioteca(s): |
Embrapa Pecuária Sudeste. |
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Data corrente: |
02/12/2020 |
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Data da última atualização: |
02/12/2020 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
DINIZ, W. J. S.; ROSA, K. O. da; TIZIOTO, P. C.; MOURÃO, G. B.; OLIVEIRA, P. S. N. de; SOUZA, M. M. de; REGITANO, L. C. de A. |
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Afiliação: |
Wellison J. S. Diniz, UFSCar; Kamila O. da Rosa, UNESP; Polyana C. Tizioto, NGS Soluções Genômicas; Gerson B. Mourão, USP, ESALQ; Priscila S. N. de Oliveira, UFSCAR; Marcela M. de Souza, Iowa State University; LUCIANA CORREIA DE ALMEIDA REGITANO, CPPSE. |
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Título: |
FABP1 and SLC2A5 expression levels affect feed efficiency-related traits. |
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Ano de publicação: |
2020 |
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Fonte/Imprenta: |
Agri Gene, v. 15, p. 1-7, e100100, mar. 2020. |
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DOI: |
https://doi.org/10.1016/j.aggene.2019.100100 |
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Idioma: |
Inglês |
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Conteúdo: |
Improving the efficiency of production to reduce the environmental footprints is pivotal to the sustainability of livestock systems. Despite the advances in cattle feed efficiency (FE) measurement and identification of potential mechanisms involved, much is still unclear regarding the genetic and biological basis of this trait. Nevertheless, lipid and carbohydrate metabolism have been outlined as important in determining efficient and inefficient animals. To address the role of genes partaking in these processes and previously involved with residual feed intake (RFI), we carried out a liver expression profile in Nelore steers (n = 83). Six target genes (FABP1, FADS2, PPP1R26, RGS2, SLC2A5, and UCP2) were measured by qPCR analysis. A general linear mixed model approach was applied to associate them with dry matter intake (DMI), body weight (BW), metabolic BW (MBW, kg), DMI as a percentage of BW (DMI%BW), and average daily gain (ADG, kg/d). Residual feed intake (RFI), feed conversion ratio (FCR), feed efficiency (FE), Kleiber index (KI), and relative growth rate (RGR) were also evaluated. Our results support that increased expression of FABP1 gene was associated with enhanced values for RFI and DMI. Likewise, higher expression level of SLC2A5 was related to higher KI and RGR. There was no phenotypic correlation between RFI and ADG, BW, and MBW. The positive correlations between FABP1 and SLC2A5, and between FABP1 and FADS2 gene expression suggest a putative co-regulation affecting feed efficiency phenotypes. MenosImproving the efficiency of production to reduce the environmental footprints is pivotal to the sustainability of livestock systems. Despite the advances in cattle feed efficiency (FE) measurement and identification of potential mechanisms involved, much is still unclear regarding the genetic and biological basis of this trait. Nevertheless, lipid and carbohydrate metabolism have been outlined as important in determining efficient and inefficient animals. To address the role of genes partaking in these processes and previously involved with residual feed intake (RFI), we carried out a liver expression profile in Nelore steers (n = 83). Six target genes (FABP1, FADS2, PPP1R26, RGS2, SLC2A5, and UCP2) were measured by qPCR analysis. A general linear mixed model approach was applied to associate them with dry matter intake (DMI), body weight (BW), metabolic BW (MBW, kg), DMI as a percentage of BW (DMI%BW), and average daily gain (ADG, kg/d). Residual feed intake (RFI), feed conversion ratio (FCR), feed efficiency (FE), Kleiber index (KI), and relative growth rate (RGR) were also evaluated. Our results support that increased expression of FABP1 gene was associated with enhanced values for RFI and DMI. Likewise, higher expression level of SLC2A5 was related to higher KI and RGR. There was no phenotypic correlation between RFI and ADG, BW, and MBW. The positive correlations between FABP1 and SLC2A5, and between FABP1 and FADS2 gene expression suggest a putative co-regulation affec... Mostrar Tudo |
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Palavras-Chave: |
Cattle feed efficiency; Relative growth rate. |
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Thesaurus Nal: |
Average daily gain; Dry matter intake; Gene expression. |
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Categoria do assunto: |
G Melhoramento Genético |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/218621/1/FABP1-SLC2A5-Expression.pdf
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Marc: |
LEADER 02342naa a2200265 a 4500
001 2127498
005 2020-12-02
008 2020 bl uuuu u00u1 u #d
024 7 $ahttps://doi.org/10.1016/j.aggene.2019.100100$2DOI
100 1 $aDINIZ, W. J. S.
245 $aFABP1 and SLC2A5 expression levels affect feed efficiency-related traits.$h[electronic resource]
260 $c2020
520 $aImproving the efficiency of production to reduce the environmental footprints is pivotal to the sustainability of livestock systems. Despite the advances in cattle feed efficiency (FE) measurement and identification of potential mechanisms involved, much is still unclear regarding the genetic and biological basis of this trait. Nevertheless, lipid and carbohydrate metabolism have been outlined as important in determining efficient and inefficient animals. To address the role of genes partaking in these processes and previously involved with residual feed intake (RFI), we carried out a liver expression profile in Nelore steers (n = 83). Six target genes (FABP1, FADS2, PPP1R26, RGS2, SLC2A5, and UCP2) were measured by qPCR analysis. A general linear mixed model approach was applied to associate them with dry matter intake (DMI), body weight (BW), metabolic BW (MBW, kg), DMI as a percentage of BW (DMI%BW), and average daily gain (ADG, kg/d). Residual feed intake (RFI), feed conversion ratio (FCR), feed efficiency (FE), Kleiber index (KI), and relative growth rate (RGR) were also evaluated. Our results support that increased expression of FABP1 gene was associated with enhanced values for RFI and DMI. Likewise, higher expression level of SLC2A5 was related to higher KI and RGR. There was no phenotypic correlation between RFI and ADG, BW, and MBW. The positive correlations between FABP1 and SLC2A5, and between FABP1 and FADS2 gene expression suggest a putative co-regulation affecting feed efficiency phenotypes.
650 $aAverage daily gain
650 $aDry matter intake
650 $aGene expression
653 $aCattle feed efficiency
653 $aRelative growth rate
700 1 $aROSA, K. O. da
700 1 $aTIZIOTO, P. C.
700 1 $aMOURÃO, G. B.
700 1 $aOLIVEIRA, P. S. N. de
700 1 $aSOUZA, M. M. de
700 1 $aREGITANO, L. C. de A.
773 $tAgri Gene$gv. 15, p. 1-7, e100100, mar. 2020.
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Registro original: |
Embrapa Pecuária Sudeste (CPPSE) |
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| Registros recuperados : 3 | |
| 2. |  | MADARI, B. E.; REEVES, J. B.; COELHO, M. R.; MACHADO, P. L. O. de A.; DE-POLLI, H.; COELHO, R. M.; BENITES, V. de M.; SOUZA, F. F. de; MCCARTY, G. W. Espectroscopia infravermelha para a determinação de carbono do solo: perspectiva de um método economicamente viável e ambientalmente seguro. Santo Antônio de Goiás: Embrapa Arroz e Feijão, 2006. 6 p. (Embrapa Arroz e Feijão. Comunicado Técnico, 126). Parcerias: Embrapa Arroz e Feijão; USDA; Embrapa Solos; IAC.| Tipo: Comunicado Técnico/Recomendações Técnicas | Circulação/Nível: -- - -- |
| Biblioteca(s): Embrapa Agrobiologia. |
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| 3. | | MADARI, B. E.; REEVES, J. B.; COELHO, M. R.; MACHADO, P. L. O. A.; DE-POLLI, H.; COELHO, R. M.; BENITES, V. M.; SOUZA, L. F.; McCARTY, G. W. Mid- and near-infrared spectroscopic determination of carbon in a diverse set of soils from the Brazilian national soil collection. Spectroscopy Letters, v. 38, n. 6, p. 721-740, 2005.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: Internacional - A |
| Biblioteca(s): Embrapa Agrobiologia; Embrapa Arroz e Feijão; Embrapa Solos. |
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| Registros recuperados : 3 | |
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| Nenhum registro encontrado para a expressão de busca informada. |
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