Data/hora: 09/06/2024 19:16:58

Biblioteca(s): | Embrapa Agricultura Digital; Embrapa Pecuária Sudeste.
Data corrente: | 11/12/2018
Data da última atualização: | 05/02/2019
Autoria: | SOUZA, M. M. de; ZERLOTINI NETO, A.; GEISTLINGER, L.; TIZIOTO, P. C.; TAYLOR, J. F.; ROCHA, M. I. P.; DINIZ, W. J. S.; COUTINHO, L. L.; REGITANO, L. C. de A.
Afiliação: | MARCELA M. DE SOUZA, UFSCar; ADHEMAR ZERLOTINI NETO, CNPTIA; LUDWIG GEISTLINGER, CPPSE; POLYANA C. TIZIOTO, NGS Genomic Solution; JEREMY F. TAYLOR, University of Missouri; MARINA I. P. ROCHA, UFSCar; WELLISON J. S. DINIZ, UFSCar; LUIZ L. COUTINHO, USP; LUCIANA CORREIA DE ALMEIDA REGITANO, CPPSE.
Título: | A comprehensive manually-curated compendium of bovine transcription factors.
Ano de publicação: | 2018
Fonte/Imprenta: | Scientific Reports, v. 8, p. 1-12, 2018.
DOI: | 10.1038/s41598-018-32146-2
Idioma: | Inglês
Notas: | Article number: 13747. Na publicação: Adhemar Zerlotini, Luciana C. A. Regitano.
Conteúdo: | Transcription factors (TFs) are pivotal regulatory proteins that control gene expression in a contextdependent and tissue-specific manner. In contrast to human, where comprehensive curated TF collections exist, bovine TFs are only rudimentary recorded and characterized. In this article, we present a manually-curated compendium of 865 sequence-specific DNA-binding bovines TFs, which we analyzed for domain family distribution, evolutionary conservation, and tissue-specific expression. In addition, we provide a list of putative transcription cofactors derived from known interactions with the identified TFs. Since there is a general lack of knowledge concerning the regulation of gene expression in cattle, the curated list of TF should provide a basis for an improved comprehension of regulatory mechanisms that are specific to the species.
Palavras-Chave: | DNA bovine; DNA bovino; Expressão gênica; Gene expression in cattle.
Thesaurus Nal: | Gene expression regulation.
Categoria do assunto: | G Melhoramento Genético

URL:

http://ainfo.cnptia.embrapa.br/digital/bitstream/item/189042/1/AP-Comprehensive-Adhemar-etal.pdf
http://ainfo.cnptia.embrapa.br/digital/bitstream/item/188184/1/ComprehensiveManuallyCurated.pdf

Registro original: | Embrapa Agricultura Digital (CNPTIA)

Exemplares:

CPPSE - (24654-1) - UPC - AP - DD - PROCI-2018.00193 - SOU - 2018.00201 - DIS
CNPTIA - (19989-1) - UPC - AP - DD -  -  -  - DIS