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Registro Completo |
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Biblioteca(s): |
Embrapa Agricultura Digital; Embrapa Milho e Sorgo. |
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Data corrente: |
23/11/2011 |
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Data da última atualização: |
28/09/2017 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
RUIZ, J. C.; D'AFONSECA, V.; SILVA, A.; ALI, A.; PINTO, A. C.; SANTOS, A. R.; ROCHA, A. A. M. C.; LOPES, D. O.; DORELLA, F. A.; PACHECO, L. G. C.; COSTA, M. P.; TURK, M. Z.; SEYFFERT, N.; MORAES, P. M. R. O.; SOARES, S. C.; ALMEIDA, S. S.; CASTRO, T. L. P.; ABREU, V. A. C.; TROST, E.; BAUMBACH, J.; TAUCH, A.; SCHNEIDER, M. P. C.; McCULLOCH, J.; CERDEIRA, L. T.; RAMOS, R. T. J.; ZERLOTINI, A.; DOMINITINI, A.; RESENDE, D. M.; COSER, E. M.; OLIVEIRA, L. M.; PEDROSA, A. L.; VIEIRA, C. U.; GUIMARAES, C. T.; BARTHOLOMEU, D. C.; OLIVEIRA, D. M.; SANTOS, F. R.; RABELO, E. M.; LOBO, F. P.; FRANCO, G. R.; COSTA, A. F.; CASTRO, I. M.; DIAS, S. R. C.; FERRO, J. A.; ORTEGA, J. M.; PAIVA, L. V.; ALMEIDA, J. F.; GOULART, L. R.; FERRO, M. I. T.; CARNEIRO, N. P.; FALCÃO, P. R. K.; GRYNBERG, P.; TEIXEIRA, S. M. R.; BROMMONSCHENKEL, S.; OLIVEIRA, S. C.; MEYER, R.; MOORE, R. J.; MIYOSHI, A.; OLIVEIRA, G. C.; AZEVEDO, V. |
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Afiliação: |
CLAUDIA TEIXEIRA GUIMARAES, CNPMS; NEWTON PORTILHO CARNEIRO, CNPMS. |
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Título: |
Evidence for reductive genome evolution and lateral acquisition of virulence functions in two Corynebacterium pseudotuberculosis strains. |
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Ano de publicação: |
2011 |
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Fonte/Imprenta: |
Plos One, San Francisco, v. 6, n. 4, p. 1-16, 2011. |
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DOI: |
10.1371/journal.pone.0018551 |
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Idioma: |
Inglês |
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Conteúdo: |
Background: Corynebacterium pseudotuberculosis, a Gram-positive, facultative intracellular pathogen, is the etiologic agent of the disease known as caseous lymphadenitis (CL). CL mainly affects small ruminants, such as goats and sheep; it also causes infections in humans, though rarely. This species is distributed worldwide, but it has the most serious economic impact in Oceania, Africa and South America. Although C. pseudotuberculosis causes major health and productivity problems for livestock, little is known about the molecular basis of its pathogenicity. Methodology and Findings: We characterized two C. pseudotuberculosis genomes (Cp1002, isolated from goats; and CpC231, isolated from sheep). Analysis of the predicted genomes showed high similarity in genomic architecture, gene content and genetic order. When C. pseudotuberculosis was compared with other Corynebacterium species, it became evident that this pathogenic species has lost numerous genes, resulting in one of the smallest genomes in the genus. Other differences that could be part of the adaptation to pathogenicity include a lower GC content, of about 52%, and a reduced gene repertoire. The C. pseudotuberculosis genome also includes seven putative pathogenicity islands, which contain several classical virulence factors, including genes for fimbrial subunits, adhesion factors, iron uptake and secreted toxins. Additionally, all of the virulence factors in the islands have characteristics that indicate horizontal transfer. Conclusions: These particular genome characteristics of C. pseudotuberculosis, as well as its acquired virulence factors in pathogenicity islands, provide evidence of its lifestyle and of the pathogenicity pathways used by this pathogen in the infection process. All genomes cited in this study are available in the NCBI Genbank database (http://www.ncbi.nlm.nih.gov/genbank/) under accession numbers CP001809 and CP001829. MenosBackground: Corynebacterium pseudotuberculosis, a Gram-positive, facultative intracellular pathogen, is the etiologic agent of the disease known as caseous lymphadenitis (CL). CL mainly affects small ruminants, such as goats and sheep; it also causes infections in humans, though rarely. This species is distributed worldwide, but it has the most serious economic impact in Oceania, Africa and South America. Although C. pseudotuberculosis causes major health and productivity problems for livestock, little is known about the molecular basis of its pathogenicity. Methodology and Findings: We characterized two C. pseudotuberculosis genomes (Cp1002, isolated from goats; and CpC231, isolated from sheep). Analysis of the predicted genomes showed high similarity in genomic architecture, gene content and genetic order. When C. pseudotuberculosis was compared with other Corynebacterium species, it became evident that this pathogenic species has lost numerous genes, resulting in one of the smallest genomes in the genus. Other differences that could be part of the adaptation to pathogenicity include a lower GC content, of about 52%, and a reduced gene repertoire. The C. pseudotuberculosis genome also includes seven putative pathogenicity islands, which contain several classical virulence factors, including genes for fimbrial subunits, adhesion factors, iron uptake and secreted toxins. Additionally, all of the virulence factors in the islands have characteristics that indicate horizontal t... Mostrar Tudo |
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Palavras-Chave: |
Análise de genoma; Genoma de C pseudotuberculosis; Ilhas de patogenicidade. |
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Thesagro: |
Corynebacterium Pseudotuberculosis; Genética; Patógeno. |
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Thesaurus Nal: |
Caseous lymphadenitis; Genome; Pathogenicity. |
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Categoria do assunto: |
--
H Saúde e Patologia |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/47474/1/Evidence-reductive.pdf
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/53621/1/journal.pone.0018551.pdf
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Marc: |
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024 7 $a10.1371/journal.pone.0018551$2DOI
100 1 $aRUIZ, J. C.
245 $aEvidence for reductive genome evolution and lateral acquisition of virulence functions in two Corynebacterium pseudotuberculosis strains.$h[electronic resource]
260 $c2011
520 $aBackground: Corynebacterium pseudotuberculosis, a Gram-positive, facultative intracellular pathogen, is the etiologic agent of the disease known as caseous lymphadenitis (CL). CL mainly affects small ruminants, such as goats and sheep; it also causes infections in humans, though rarely. This species is distributed worldwide, but it has the most serious economic impact in Oceania, Africa and South America. Although C. pseudotuberculosis causes major health and productivity problems for livestock, little is known about the molecular basis of its pathogenicity. Methodology and Findings: We characterized two C. pseudotuberculosis genomes (Cp1002, isolated from goats; and CpC231, isolated from sheep). Analysis of the predicted genomes showed high similarity in genomic architecture, gene content and genetic order. When C. pseudotuberculosis was compared with other Corynebacterium species, it became evident that this pathogenic species has lost numerous genes, resulting in one of the smallest genomes in the genus. Other differences that could be part of the adaptation to pathogenicity include a lower GC content, of about 52%, and a reduced gene repertoire. The C. pseudotuberculosis genome also includes seven putative pathogenicity islands, which contain several classical virulence factors, including genes for fimbrial subunits, adhesion factors, iron uptake and secreted toxins. Additionally, all of the virulence factors in the islands have characteristics that indicate horizontal transfer. Conclusions: These particular genome characteristics of C. pseudotuberculosis, as well as its acquired virulence factors in pathogenicity islands, provide evidence of its lifestyle and of the pathogenicity pathways used by this pathogen in the infection process. All genomes cited in this study are available in the NCBI Genbank database (http://www.ncbi.nlm.nih.gov/genbank/) under accession numbers CP001809 and CP001829.
650 $aCaseous lymphadenitis
650 $aGenome
650 $aPathogenicity
650 $aCorynebacterium Pseudotuberculosis
650 $aGenética
650 $aPatógeno
653 $aAnálise de genoma
653 $aGenoma de C pseudotuberculosis
653 $aIlhas de patogenicidade
700 1 $aD'AFONSECA, V.
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700 1 $aTURK, M. Z.
700 1 $aSEYFFERT, N.
700 1 $aMORAES, P. M. R. O.
700 1 $aSOARES, S. C.
700 1 $aALMEIDA, S. S.
700 1 $aCASTRO, T. L. P.
700 1 $aABREU, V. A. C.
700 1 $aTROST, E.
700 1 $aBAUMBACH, J.
700 1 $aTAUCH, A.
700 1 $aSCHNEIDER, M. P. C.
700 1 $aMcCULLOCH, J.
700 1 $aCERDEIRA, L. T.
700 1 $aRAMOS, R. T. J.
700 1 $aZERLOTINI, A.
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700 1 $aRESENDE, D. M.
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700 1 $aOLIVEIRA, L. M.
700 1 $aPEDROSA, A. L.
700 1 $aVIEIRA, C. U.
700 1 $aGUIMARAES, C. T.
700 1 $aBARTHOLOMEU, D. C.
700 1 $aOLIVEIRA, D. M.
700 1 $aSANTOS, F. R.
700 1 $aRABELO, E. M.
700 1 $aLOBO, F. P.
700 1 $aFRANCO, G. R.
700 1 $aCOSTA, A. F.
700 1 $aCASTRO, I. M.
700 1 $aDIAS, S. R. C.
700 1 $aFERRO, J. A.
700 1 $aORTEGA, J. M.
700 1 $aPAIVA, L. V.
700 1 $aALMEIDA, J. F.
700 1 $aGOULART, L. R.
700 1 $aFERRO, M. I. T.
700 1 $aCARNEIRO, N. P.
700 1 $aFALCÃO, P. R. K.
700 1 $aGRYNBERG, P.
700 1 $aTEIXEIRA, S. M. R.
700 1 $aBROMMONSCHENKEL, S.
700 1 $aOLIVEIRA, S. C.
700 1 $aMEYER, R.
700 1 $aMOORE, R. J.
700 1 $aMIYOSHI, A.
700 1 $aOLIVEIRA, G. C.
700 1 $aAZEVEDO, V.
773 $tPlos One, San Francisco$gv. 6, n. 4, p. 1-16, 2011.
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Registro original: |
Embrapa Milho e Sorgo (CNPMS) |
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| Registros recuperados : 147 | |
| 141. |  | CORACINI, M. D. A.; BONEZ, C.; KRUGER, L. R.; KOVALESKI, A.; ZARBIN, P. H. G.; VIVELA, E. F.; GRUTZMACHER, A. D. Utilização de confusão sexual para o controle de Grapholita molesta (Lepidoptera: Tortricidae) em pomares de pêssego. In: CONGRESSO BRASILEIRO DE ENTOMOLOGIA, 22., 2008, Uberlândia. Ciência, tecnologia e inovação: anais. Viçosa: UFV, 2008. Não paginado. 1 CD-ROM. Resumo 1090-1.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Uva e Vinho. |
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| 142. | | MARTINS, J. F. da S.; ANDRES, A.; ROSA, A. P. S. A. da; GRÜTZMACHER, A. D.; NUNES, C. D. M.; PAZINI, J. de B.; VISOLI, M. C.; MATTOS, M. L. T. Adequação Agronômica, Toxicológica e Ambiental de Agrotóxicos Utilizados no Controle de Pragas do Arroz, Milho e Soja em Terras Baixas no Rio Grande do Sul. Pelotas: Embrapa Clima Temperado, 2016. 26 p. (Embrapa Clima Temperado. Circular Técnica, 176.)| Biblioteca(s): Embrapa Clima Temperado. |
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| 143. | | PAZINI, J. DE B.; GRÜTZMACHER, A. D.; SEIDEL, E. J.; VIEIRA, A. M. C.; PADILHA, A. C.; BRITO, G. G. de; BERNARDI, D.; BARRIGOSSI, J. A. F.; MARTINS, J. F. da S. Differential response to the South American rice water weevil (Coleoptera: Curculionidae) damage of rice cultivars with contrasting levels of resistance: implications for field management. Pest Management Science, v. 79, n. 3, p. 947-958, Mar. 2023.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
| Biblioteca(s): Embrapa Arroz e Feijão; Embrapa Clima Temperado. |
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| 144. | | MARTINS, J. F. da S.; CUNHA, U. S.; GRÜTZMACHER, A. D.; MATTOS, M. L. T.; NEVES, M. B.; HÄRTER, W. da R.; TRECHA, C. de O.; JARDIM, E. de O.; THOMAZ, L. F. Efeito de doses de inseticidas aplicadas às sementes de arroz no controle do gorgulho-aquático Oryzophagus oryzae. In: CONGRESSO BRASILEIRO DE ARROZ IRRIGADO, 5.; REUNIÃO DA CULTURA DO ARROZ IRRIGADO, 27., 2007, Pelotas. Anais... Pelotas: Embrapa Clima Temperado, 2007. v. 1, p. 45-47| Tipo: Artigo em Anais de Congresso / Nota Técnica | Circulação/Nível: -- - -- |
| Biblioteca(s): Embrapa Clima Temperado. |
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| 145. | | CUNHA, U. S.; MARTINS, J. F. da S.; GRÜTZMACHER, A. D.; MATTOS, M. L. T.; BOGORNI, P. C.; NEVES, M. B. das; JARDIM, E. de O.; TRECHA, C. de O. Potencial de inseticidas derivados de NIM para controle do gorgulho-aquático Oryzophagus oryzae e aplicação em sistemas sustentáveis de produção de arroz. In: CONGRESSO BRASILEIRO DE ARROZ IRRIGADO, 5.; REUNIÃO DA CULTURA DO ARROZ IRRIGADO, 27., 2007, Pelotas. Anais... Pelotas: Embrapa Clima Temperado, 2007. v. 1, p. 48-50| Tipo: Artigo em Anais de Congresso / Nota Técnica | Circulação/Nível: -- - -- |
| Biblioteca(s): Embrapa Clima Temperado. |
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| 146. | | PAZINI, J. de B.; BUENO, F. A.; AGUILHERA, J. O. de S.; TREPTOW, G. T.; SEIDEL, E. J.; BRITO, G. G. de; BARRIGOSSI, J. A. F.; GRÜTZMACHER, A. D.; MARTINS, J. F. da S. Estudo atualiza nível de controle da bicheira-da-raiz em arroz. In: CONGRESSO BRASILEIRO DE ARROZ IRRIGADO, 11., 2019. Balneário Camboriú, SC. Inovação e desenvolvimento na orizicultura: anais eletrônico. Itajaí: Epagri: Sosbai, 2019.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Arroz e Feijão. |
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| 147. | | GRÜTZMACHER, A. D.; MARTINS, J. F. da S.; CUNHA, U. S. da; GIOLO, F. P.; NEVES, M. B. das; HÄRTER, W. da R.; FRNACO, D. F.; MATTOS, M. L. T. Viabilidade da antecipação do tratamento de sementes de arroz com inseticidas em relação à data de semeadura no controle de Oryzophagus oryzae (Coleoptera: Curculionidae) Ciencia rural, Santa Maria, v. 38, n. 7, p. 1830-1835, 2008.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: Nacional - A |
| Biblioteca(s): Embrapa Clima Temperado. |
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| Registros recuperados : 147 | |
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| Nenhum registro encontrado para a expressão de busca informada. |
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