Data/hora: 05/06/2024 06:45:19

Biblioteca(s): | Embrapa Agroindústria de Alimentos.
Data corrente: | 05/04/2021
Data da última atualização: | 15/06/2021
Autoria: | GONÇALVES, G. M.; MARTINS, V. de C.; COSTA, A. R. H. da; FERNANDES, T. F. da C.; PACHECO, S.; GAMA, P. E.; SOUZA, M. da C.; GODOY, R. L. de O.; LAUREANO-MELO, R.; CÔRTES, W. da S.; CARVALHO, M. G. de; MARINHO, B. G.
Afiliação: | GABRIELA MASTRANGELO GONÇALVES, UFRRJ; VÍCTOR DE CARVALHO MARTINS, UFRRJ; ANDRÉ ROMERO HENRIQUE DA COSTA, UFRRJ; THAYANE FERREIRA DA COSTA FERNANDES, Universidade Federal Fluminense, Rio das Ostras; SIDNEY PACHECO, CTAA; PAOLA ERVATTI GAMA, CTAA; MARCELO DA COSTA SOUZA, Herbário RBR, Instituto de Ciências Biológicas e da Saúde, UFRRJ; RONOEL LUIZ DE OLIVEIRA GODOY, CTAA; ROBERTO LAUREANO-MELO, Centro Universitário de Barra Mansa; WELLINGTON DA SILVA CÔRTES, UFRRJ; MARIO GERALDO DE CARVALHO, UFRRJ; BRUNO GUIMARÃES MARINHO, UFRRJ.
Título: | Essential oil of Myrciaria tenella (DC.) O. Berg:effects of distillation time on its chemicalcomposition and evaluation of its anti-inflammatory and antinociceptive effects.
Ano de publicação: | 2021
Fonte/Imprenta: | The Journal Of Essential Oil Reseach, 2021. p. 1-17.
DOI: | https://doi.org/10.1080/10412905.2021.1899993
Idioma: | Inglês
Conteúdo: | The objective of the present study was to characterize the essential oil of Myrciaria tenella (MTEO) leaves, to determine the effects of distillation time (1 to 5 h), and to evaluate its action on acute pain and inflammation both in vivo and in vitro. MTEO was obtained by hydrodistillation for 4 h and 36 compounds were detected, mainly consisting of hydrocarbon terpenes such as &#946;-pinene (21.46%), &#945;-pinene (19.43%), E-caryophyllene (10.89%) and aromadendrene (9.17%). A high yield of &#945;-pinene/&#946;-pinene-rich MTEO was obtained after only 2 h of extraction. For in vivo biological assays, MTEO was administered to male Swiss mice, showing an action against hypernociception (acetic acid-induced abdominal writhing, formalin and Von Frey models) and inhibiting carrageenan-induced paw edema. Production of IL-6, TNF-&#945;, IL-1&#946;, PGE2 was reduced and production of IL-10 was increased, with no change in motor performance. MTEO also reduced cell production of NO and cytokines, in addition to inhibiting COX activity.
Palavras-Chave: | Citocinas; Hipernocicepção inflamatória; Inflammatory hypernociception; Myrciaria tenella; Ratos; Terpenes.
Thesagro: | Óleo Essencial; Produto de Origem Vegetal.
Thesaurus Nal: | Cytokinesis; Essential oils; Mice; Myrciaria; Vegetable products.
Categoria do assunto: | X Pesquisa, Tecnologia e Engenharia
Registro original: | Embrapa Agroindústria de Alimentos (CTAA)
Exemplares: | CTAA - (15152-1) - UPC - AP - DD -  -  -  - DIS