|
|
Registro Completo |
Biblioteca(s): |
Embrapa Agricultura Digital; Embrapa Pecuária Sudeste. |
Data corrente: |
08/09/2020 |
Data da última atualização: |
10/09/2020 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Autoria: |
AFONSO, J.; FORTES, M. R. S.; REVERTER, A.; DINIZ, W. J. da S.; CESAR, A. S. M.; LIMA, A. O. de; PETRINI, J.; SOUZA, M. de S.; COUTINHO, L. L.; MOURÃO, G. B.; ZERLOTINI NETO, A.; GROMBONI, C. F.; NOGUEIRA, A. R. A.; REGITANO, L. C. de A. |
Afiliação: |
JULIANA AFONSO, UFSCar; MARINA RUFINO SALINAS FORTES, The University of Queensland; ANTONIO REVERTER, Agriculture and Food, Commonwealth Scientific and Industrial Research Organisation, Brisbane; WELLISON JARLES DA SILVA DINIZ, UFSCar; ALINE SILVA MELLO CESAR, Esalq/USP; ANDRESSA OLIVEIRA DE LIMA, UFSCar; JULIANA PETRINI, UNIFAL; MARCELA M. DE SOUZA, Iowa State University; LUIZ LEHMANN COUTINHO, Esalq/USP; GERSON BARRETO MOURÃO, Esalq/USP; ADHEMAR ZERLOTINI NETO, CNPTIA; CAIO FERNANDO GROMBONI, Bahia Federal Institute of Education, Science and Technology, Ilhéus; ANA RITA ARAÚJO NOGUEIRA; LUCIANA CORREIA DE ALMEIDA REGITANO, CPPSE. |
Título: |
Genetic regulators of mineral amount in Nelore cattle muscle predicted by a new co-expression and regulatory impact factor approach. |
Ano de publicação: |
2020 |
Fonte/Imprenta: |
Scientific Reports, v. 10, n. 1, p. 1-16, 2020 |
DOI: |
https://doi.org/10.1038/s41598-020-65454-7 |
Idioma: |
Inglês |
Notas: |
Article: 8436. |
Conteúdo: |
Mineral contents in bovine muscle can affect meat quality, growth, health, and reproductive traits. To better understand the genetic basis of this phenotype in Nelore (Bos indicus) cattle, we analysed genome-wide mRNA and miRNA expression data from 114 muscle samples. The analysis implemented a new application for two complementary algorithms: the partial correlation and information theory (PCIT) and the regulatory impact factor (RIF), in which we included the estimated genomic breeding values (GEBVs) for the phenotypes additionally to the expression levels, originally proposed for these methods. We used PCIT to determine putative regulatory relationships based on significant associations between gene expression and GEBVs for each mineral amount. Then, RIF was adopted to determine the regulatory impact of genes and miRNAs expression over the GEBVs for the mineral amounts. We also investigated over-represented pathways, as well as pieces of evidences from previous studies carried in the same population and in the literature, to determine regulatory genes for the mineral amounts. For example, NOX1 expression level was positively correlated to Zinc and has been described as Zinc-regulated in humans. Based on our approach, we were able to identify genes, miRNAs and pathways not yet described as underlying mineral amount. The results support the hypothesis that extracellular matrix interactions are the core regulator of mineral amount in muscle cells. Putative regulators described here add information to this hypothesis, expanding the knowledge on molecular relationships between gene expression and minerals. MenosMineral contents in bovine muscle can affect meat quality, growth, health, and reproductive traits. To better understand the genetic basis of this phenotype in Nelore (Bos indicus) cattle, we analysed genome-wide mRNA and miRNA expression data from 114 muscle samples. The analysis implemented a new application for two complementary algorithms: the partial correlation and information theory (PCIT) and the regulatory impact factor (RIF), in which we included the estimated genomic breeding values (GEBVs) for the phenotypes additionally to the expression levels, originally proposed for these methods. We used PCIT to determine putative regulatory relationships based on significant associations between gene expression and GEBVs for each mineral amount. Then, RIF was adopted to determine the regulatory impact of genes and miRNAs expression over the GEBVs for the mineral amounts. We also investigated over-represented pathways, as well as pieces of evidences from previous studies carried in the same population and in the literature, to determine regulatory genes for the mineral amounts. For example, NOX1 expression level was positively correlated to Zinc and has been described as Zinc-regulated in humans. Based on our approach, we were able to identify genes, miRNAs and pathways not yet described as underlying mineral amount. The results support the hypothesis that extracellular matrix interactions are the core regulator of mineral amount in muscle cells. Putative regulators describe... Mostrar Tudo |
Palavras-Chave: |
Expressão gênica. |
Thesagro: |
Bos Indicus; Gado Nelore. |
Thesaurus Nal: |
Cattle; Gene expression. |
Categoria do assunto: |
-- G Melhoramento Genético |
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/215819/1/AP-Genetic-regulators-2020.pdf
|
Marc: |
LEADER 02716naa a2200361 a 4500 001 2124802 005 2020-09-10 008 2020 bl uuuu u00u1 u #d 024 7 $ahttps://doi.org/10.1038/s41598-020-65454-7$2DOI 100 1 $aAFONSO, J. 245 $aGenetic regulators of mineral amount in Nelore cattle muscle predicted by a new co-expression and regulatory impact factor approach.$h[electronic resource] 260 $c2020 500 $aArticle: 8436. 520 $aMineral contents in bovine muscle can affect meat quality, growth, health, and reproductive traits. To better understand the genetic basis of this phenotype in Nelore (Bos indicus) cattle, we analysed genome-wide mRNA and miRNA expression data from 114 muscle samples. The analysis implemented a new application for two complementary algorithms: the partial correlation and information theory (PCIT) and the regulatory impact factor (RIF), in which we included the estimated genomic breeding values (GEBVs) for the phenotypes additionally to the expression levels, originally proposed for these methods. We used PCIT to determine putative regulatory relationships based on significant associations between gene expression and GEBVs for each mineral amount. Then, RIF was adopted to determine the regulatory impact of genes and miRNAs expression over the GEBVs for the mineral amounts. We also investigated over-represented pathways, as well as pieces of evidences from previous studies carried in the same population and in the literature, to determine regulatory genes for the mineral amounts. For example, NOX1 expression level was positively correlated to Zinc and has been described as Zinc-regulated in humans. Based on our approach, we were able to identify genes, miRNAs and pathways not yet described as underlying mineral amount. The results support the hypothesis that extracellular matrix interactions are the core regulator of mineral amount in muscle cells. Putative regulators described here add information to this hypothesis, expanding the knowledge on molecular relationships between gene expression and minerals. 650 $aCattle 650 $aGene expression 650 $aBos Indicus 650 $aGado Nelore 653 $aExpressão gênica 700 1 $aFORTES, M. R. S. 700 1 $aREVERTER, A. 700 1 $aDINIZ, W. J. da S. 700 1 $aCESAR, A. S. M. 700 1 $aLIMA, A. O. de 700 1 $aPETRINI, J. 700 1 $aSOUZA, M. de S. 700 1 $aCOUTINHO, L. L. 700 1 $aMOURÃO, G. B. 700 1 $aZERLOTINI NETO, A. 700 1 $aGROMBONI, C. F. 700 1 $aNOGUEIRA, A. R. A. 700 1 $aREGITANO, L. C. de A. 773 $tScientific Reports$gv. 10, n. 1, p. 1-16, 2020
Download
Esconder MarcMostrar Marc Completo |
Registro original: |
Embrapa Agricultura Digital (CNPTIA) |
|
Biblioteca |
ID |
Origem |
Tipo/Formato |
Classificação |
Cutter |
Registro |
Volume |
Status |
URL |
Voltar
|
|
Registro Completo
Biblioteca(s): |
Embrapa Unidades Centrais. |
Data corrente: |
29/05/2023 |
Data da última atualização: |
26/01/2024 |
Autoria: |
GONZÁLEZ-MALDONADO, J.; TEJEDA-SARTORIUS, O.; RAMÍREZ-RAMÍREZ, A. I.; GALLEGOS-SÁNCHEZ, J. |
Afiliação: |
JUAN GONZÁLEZ-MALDONADO, UNIVERSIDAD AUTÓNOMA DE BAJA CALIFORNIA; OLGA TEJEDA-SARTORIUS, COLEGIO DE POSTGRADUADOS; ANAYANSI IVETTE RAMÍREZ-RAMÍREZ, COLEGIO DE POSTGRADUADOS; JAIME GALLEGOS-SÁNCHEZ, COLEGIO DE POSTGRADUADOS. |
Título: |
Reproductive performance of hair sheep under different body conditions and feeding levels. |
Ano de publicação: |
2023 |
Fonte/Imprenta: |
Pesquisa Agropecuária Brasileira, v. 58, e03092, 2023. |
DOI: |
https://doi.org/10.1590/S1678-3921.pab2023.v58.03092 |
Idioma: |
Inglês |
Notas: |
Título em português: Desempenho reprodutivo de ovelhas de pelo em diferentes condições corporais e níveis de alimentação. |
Conteúdo: |
ABSTRACT - The objective of this work was to evaluate the effect of the interaction between feeding level (FL) and body condition score (BCS) on the reproductive parameters of Pelibuey hair sheep (Ovis aries). The experimental units (64 ewes) were randomly assigned to one of four treatments: low feeding level and low body condition score; high feeding level and low body condition score; low feeding level and high body condition score; and high feeding level and high body condition score. The effect of sheep body condition score was significant on the pregnancy and lambing rates. The effect of feeding level was significant on the ovulation, estrus returning, pregnancy, and prolificacy rates. The interaction effect between BCS and FL was significant on the ovulation, estrus returning, pregnancy, lambing, and prolificacy rates. The reproductive function is more sensitive to the better nutrition effects in sheep with a low body condition score. RESUMO - O objetivo deste trabalho foi avaliar o efeito da interação entre nível de alimentação (FL) e escore de condição corporal (BCS) sobre os parâmetros reprodutivos de ovelhas de pelo Pelibuey (Ovis aries). As unidades experimentais (64 ovelhas) foram distribuídas aleatoriamente a um dos quatro tratamentos: baixo nível de alimentação e baixo escore de condição corporal; alto nível de alimentação e baixo escore nas condições corporais; baixo nível de alimentação e alto escore nas condições corporais; e alto nível de alimentação e alto escore nas condições corporais. O efeito do escore de condição corporal de ovelhas foi significativo sobre as taxas de prenhez e parto. O efeito do nível de alimentação foi significativo sobre as taxas de ovulação, retorno do estro, prenhez e prolificidade. O efeito da interação entre escore de condição corporal e nível de alimentação foi significativo sobre as taxas de ovulação, retorno do estro, prenhez, parto e prolificidade. A função reprodutiva é mais sensível aos melhores efeitos nutricionais em ovelhas com baixo escore de condição corporal. MenosABSTRACT - The objective of this work was to evaluate the effect of the interaction between feeding level (FL) and body condition score (BCS) on the reproductive parameters of Pelibuey hair sheep (Ovis aries). The experimental units (64 ewes) were randomly assigned to one of four treatments: low feeding level and low body condition score; high feeding level and low body condition score; low feeding level and high body condition score; and high feeding level and high body condition score. The effect of sheep body condition score was significant on the pregnancy and lambing rates. The effect of feeding level was significant on the ovulation, estrus returning, pregnancy, and prolificacy rates. The interaction effect between BCS and FL was significant on the ovulation, estrus returning, pregnancy, lambing, and prolificacy rates. The reproductive function is more sensitive to the better nutrition effects in sheep with a low body condition score. RESUMO - O objetivo deste trabalho foi avaliar o efeito da interação entre nível de alimentação (FL) e escore de condição corporal (BCS) sobre os parâmetros reprodutivos de ovelhas de pelo Pelibuey (Ovis aries). As unidades experimentais (64 ovelhas) foram distribuídas aleatoriamente a um dos quatro tratamentos: baixo nível de alimentação e baixo escore de condição corporal; alto nível de alimentação e baixo escore nas condições corporais; baixo nível de alimentação e alto escore nas condições corporais; e alto nível de alimentação e alto... Mostrar Tudo |
Thesagro: |
Nutrição Animal; Ovelha; Ovis Aries; Ovulação; Parto; Prenhez. |
Thesaurus NAL: |
Estrus; Lambing rate; Ovulation; Pregnancy rate; Sheep. |
Categoria do assunto: |
-- |
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/doc/1154060/1/Reproductive-performance-hair-sheep-2023.pdf
|
Marc: |
LEADER 03129naa a2200313 a 4500 001 2154060 005 2024-01-26 008 2023 bl uuuu u00u1 u #d 024 7 $ahttps://doi.org/10.1590/S1678-3921.pab2023.v58.03092$2DOI 100 1 $aGONZÁLEZ-MALDONADO, J. 245 $aReproductive performance of hair sheep under different body conditions and feeding levels.$h[electronic resource] 260 $c2023 500 $aTítulo em português: Desempenho reprodutivo de ovelhas de pelo em diferentes condições corporais e níveis de alimentação. 520 $aABSTRACT - The objective of this work was to evaluate the effect of the interaction between feeding level (FL) and body condition score (BCS) on the reproductive parameters of Pelibuey hair sheep (Ovis aries). The experimental units (64 ewes) were randomly assigned to one of four treatments: low feeding level and low body condition score; high feeding level and low body condition score; low feeding level and high body condition score; and high feeding level and high body condition score. The effect of sheep body condition score was significant on the pregnancy and lambing rates. The effect of feeding level was significant on the ovulation, estrus returning, pregnancy, and prolificacy rates. The interaction effect between BCS and FL was significant on the ovulation, estrus returning, pregnancy, lambing, and prolificacy rates. The reproductive function is more sensitive to the better nutrition effects in sheep with a low body condition score. RESUMO - O objetivo deste trabalho foi avaliar o efeito da interação entre nível de alimentação (FL) e escore de condição corporal (BCS) sobre os parâmetros reprodutivos de ovelhas de pelo Pelibuey (Ovis aries). As unidades experimentais (64 ovelhas) foram distribuídas aleatoriamente a um dos quatro tratamentos: baixo nível de alimentação e baixo escore de condição corporal; alto nível de alimentação e baixo escore nas condições corporais; baixo nível de alimentação e alto escore nas condições corporais; e alto nível de alimentação e alto escore nas condições corporais. O efeito do escore de condição corporal de ovelhas foi significativo sobre as taxas de prenhez e parto. O efeito do nível de alimentação foi significativo sobre as taxas de ovulação, retorno do estro, prenhez e prolificidade. O efeito da interação entre escore de condição corporal e nível de alimentação foi significativo sobre as taxas de ovulação, retorno do estro, prenhez, parto e prolificidade. A função reprodutiva é mais sensível aos melhores efeitos nutricionais em ovelhas com baixo escore de condição corporal. 650 $aEstrus 650 $aLambing rate 650 $aOvulation 650 $aPregnancy rate 650 $aSheep 650 $aNutrição Animal 650 $aOvelha 650 $aOvis Aries 650 $aOvulação 650 $aParto 650 $aPrenhez 700 1 $aTEJEDA-SARTORIUS, O. 700 1 $aRAMÍREZ-RAMÍREZ, A. I. 700 1 $aGALLEGOS-SÁNCHEZ, J. 773 $tPesquisa Agropecuária Brasileira$gv. 58, e03092, 2023.
Download
Esconder MarcMostrar Marc Completo |
Registro original: |
Embrapa Unidades Centrais (AI-SEDE) |
|
Biblioteca |
ID |
Origem |
Tipo/Formato |
Classificação |
Cutter |
Registro |
Volume |
Status |
Fechar
|
Expressão de busca inválida. Verifique!!! |
|
|