| |
|
|
|
Registro Completo |
|
Biblioteca(s): |
Embrapa Unidades Centrais. |
|
Data corrente: |
29/03/2018 |
|
Data da última atualização: |
29/03/2018 |
|
Autoria: |
SOUZA, A. J. S. de; MALHEIROS, A. P.; SOARES, M. do C. P.; GOMES-GOUVÊA, M. S.; PINHO, J. R. R.; PEREIRA, W. L. A.; SÁ, L. R. M. |
|
Afiliação: |
Alex J. S. de Souza, Departamento de Patologia/Faculdade de Medicina Veterinária e Zootecnia/Universidade de São Paulo - USP; Andreza P. Malheiros, Seção de Hepatologia/Instituto Evandro Chagas/IEC/SVS/MS; Manoel do C. P. Soares, Seção de Hepatologia/Instituto Evandro Chagas/IEC/SVS/MS; Michele S. Gomes-Gouvêa, Instituto de Medicina Tropical/Faculdade de Medicina/USP; João R. R. Pinho, Instituto de Medicina Tropical/Faculdade de Medicina/USP; Washington L. A. Pereira, Instituto da Saúde e da Produção Animal/Universidade Federal Rural da Amazônia - UFRA; Lilian R. M. Sá, Departamento de Patologia/Faculdade de Medicina Veterinária e Zootecnia/Universidade de São Paulo - USP. |
|
Título: |
Hallmarks of liver lesions in pigs naturally infected by hepatitis E virus genotype. |
|
Ano de publicação: |
2018 |
|
Fonte/Imprenta: |
Pesquisa Veterinária Brasileira, Rio de Janeiro, v. 38, n. 1, p. 65-70, janeiro 2018. |
|
Idioma: |
Inglês |
|
Notas: |
Título em português: Perfil das lesões histopatológicas hepáticas em suínos infectados naturalmente pelo genótipo 3 do vírus da hepatite E. |
|
Conteúdo: |
Histopathological evaluation of liver from 33 pigs slaughtered for human consumption in Amazon region, previously tested by serology and molecular techniques for hepatitis E virus infection (HEV), was analysed in three groups: Group 1, negative for both HEV-RNA and anti-HEV IgG (n=10); Group 2, positive for HEV-RNA (n=13); Group 3, positive for anti- HEV IgG (n=10). Group 2 showed a significant difference among the groups for liver lesions such as lobular activity (P=0.007), periportal interface he patitis (P=0.004), portal inflammation (P=0.028) hepatitis with lobular, portal and periportal interface activity (P=0.001). HEV detection by immunohistochemistry was performed and 3 of 6 samples of group 2 were positive. Pigs naturally infected by HEV genotype 3 present microscopic necroinflammatory liver lesions similar to HEV in humans. Liver histopathology showed be important in the diagnosis of active asymptomatic HEV infection in pigs slaughtered for human consumption because hepatic liver lesions may present distinct profiles according to molecular and serological diagnosis and in this sense, histopathology and immunohistochemistry may be an important complementary diagnostic tool. |
|
Palavras-Chave: |
Genotype 3; Imunohistoquímica; Pathology. |
|
Thesagro: |
Doença; Histopatologia; Suíno; Zoonose. |
|
Thesaurus Nal: |
Hepatitis; Hepatitis E virus; Histopathology; Immunohistochemistry; Liver; Swine; Zoonoses. |
|
Categoria do assunto: |
-- |
|
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/174785/1/Hallmarks-of-liver-lesions-in-pigs-naturally.pdf
|
|
Marc: |
LEADER 02376naa a2200373 a 4500
001 2089989
005 2018-03-29
008 2018 bl uuuu u00u1 u #d
100 1 $aSOUZA, A. J. S. de
245 $aHallmarks of liver lesions in pigs naturally infected by hepatitis E virus genotype.$h[electronic resource]
260 $c2018
500 $aTítulo em português: Perfil das lesões histopatológicas hepáticas em suínos infectados naturalmente pelo genótipo 3 do vírus da hepatite E.
520 $aHistopathological evaluation of liver from 33 pigs slaughtered for human consumption in Amazon region, previously tested by serology and molecular techniques for hepatitis E virus infection (HEV), was analysed in three groups: Group 1, negative for both HEV-RNA and anti-HEV IgG (n=10); Group 2, positive for HEV-RNA (n=13); Group 3, positive for anti- HEV IgG (n=10). Group 2 showed a significant difference among the groups for liver lesions such as lobular activity (P=0.007), periportal interface he patitis (P=0.004), portal inflammation (P=0.028) hepatitis with lobular, portal and periportal interface activity (P=0.001). HEV detection by immunohistochemistry was performed and 3 of 6 samples of group 2 were positive. Pigs naturally infected by HEV genotype 3 present microscopic necroinflammatory liver lesions similar to HEV in humans. Liver histopathology showed be important in the diagnosis of active asymptomatic HEV infection in pigs slaughtered for human consumption because hepatic liver lesions may present distinct profiles according to molecular and serological diagnosis and in this sense, histopathology and immunohistochemistry may be an important complementary diagnostic tool.
650 $aHepatitis
650 $aHepatitis E virus
650 $aHistopathology
650 $aImmunohistochemistry
650 $aLiver
650 $aSwine
650 $aZoonoses
650 $aDoença
650 $aHistopatologia
650 $aSuíno
650 $aZoonose
653 $aGenotype 3
653 $aImunohistoquímica
653 $aPathology
700 1 $aMALHEIROS, A. P.
700 1 $aSOARES, M. do C. P.
700 1 $aGOMES-GOUVÊA, M. S.
700 1 $aPINHO, J. R. R.
700 1 $aPEREIRA, W. L. A.
700 1 $aSÁ, L. R. M.
773 $tPesquisa Veterinária Brasileira, Rio de Janeiro$gv. 38, n. 1, p. 65-70, janeiro 2018.
Download
Esconder MarcMostrar Marc Completo |
|
Registro original: |
Embrapa Unidades Centrais (AI-SEDE) |
|
|
Biblioteca |
ID |
Origem |
Tipo/Formato |
Classificação |
Cutter |
Registro |
Volume |
Status |
URL |
Voltar
|
|
|
| Registros recuperados : 1 | |
| Registros recuperados : 1 | |
|
| Nenhum registro encontrado para a expressão de busca informada. |
|
|
