Data/hora: 14/06/2024 12:19:09

Biblioteca(s): | Embrapa Instrumentação.
Data corrente: | 20/04/2023
Data da última atualização: | 15/01/2024
Autoria: | GOMES, N. O.; PASCHOALIN, R. T.; BILLATO, S.; SORIGOTTI, A. R.; FARINAS, C. S.; MATTOSO, L. H. C.; MACHADO, S. A. S.; OLIVEIRA JR., O. N.; RAYMUNDO-PEREIRA, P. A.
Afiliação: | CRISTIANE SANCHEZ FARINAS, CNPDIA; LUIZ HENRIQUE CAPPARELLI MATTOSO, CNPDIA.
Título: | Flexible, Bifunctional Sensing Platform Made with Biodegradable Mats for Detecting Glucose in Urine.
Ano de publicação: | 2023
Fonte/Imprenta: | ACS Sustainable Chemistry & Engineering, v. 11, 2023.
Páginas: | 2209–2218
ISSN: | 2168-0485
DOI: | https://doi.org/10.1021/acssuschemeng.2c05438
Idioma: | Inglês
Conteúdo: | : We report on a flexible, bifunctional platform made with solution-blow spinning fiber mats of polylactic acid (PLA) and polyethylene glycol (PEG). The PLA/PEG mats were designated bifunctional because they were used as a substrate for screenprinted carbon electrodes (SPCEs) and as a matrix to attach glucose oxidase (GOx)covalently. By attaching GOx only on the fiber mats, and not on the SPCE, the detectionof hydrogen peroxide generated from glucose oxidation by the enzyme was efficient,especially with Prussian blue (PB) nanoparticles electrodeposited on the SPCE surface.The bifunctional device detected hydrogen peroxide (H2O2) in synthetic and humanurine at a low applied potential (0 V vs Ag/AgCl) in the range from 1.0 to 6.0 mM, witha detection limit of 0.197 mM, being also interference-free. The biosensor whose cost is<US$ 0.25 per unit (estimated from the price of the materials used) had performance comparable to the gold standard method while measuring glucose in human urine samples, in addition to exhibiting a rapid response and long lifetime. The design of the bifunctional device is generic and may be extended to other biosensors for on-site monitoring as well as for wearable devices and inmonitoring the environment and water in varied resources
Palavras-Chave: | Biodegradable and biocompatible mat; Glucose electrochemical biosensor; Polylactic acid (PLA); Solution-blow spinning; Urine non-invasive sample.
Categoria do assunto: | --
Registro original: | Embrapa Instrumentação (CNPDIA)
Exemplares: | CNPDIA - (18219-1) - UPC - AP - DD - PROCI.23/34 -  - 2023/38 - DIS