| |
|
|
|
Registro Completo |
|
Biblioteca(s): |
Embrapa Florestas; Embrapa Recursos Genéticos e Biotecnologia. |
|
Data corrente: |
17/05/2017 |
|
Data da última atualização: |
31/03/2023 |
|
Tipo da produção científica: |
Artigo em Periódico Indexado |
|
Autoria: |
RESENDE, R. T.; RESENDE, M. D. V. de; SILVA, F. F. S.; AZEVEDO, C. F. A.; TAKAHASHI, E. K. T.; SILVA JUNIOR, O. B. da; GRATTAPAGLIA, D. |
|
Afiliação: |
RAFAEL TASSINARI RESENDE, UNIVERSIDADE FEDERAL DE VIÇOSA; MARCOS DEON VILELA DE RESENDE, CNPF; FABYANO FONSECA SILVA, UNIVERSIDADE FEDERAL DE VIÇOSA; CAMILA FERREIRA AZEVEDO, UNIVERSIDADE FEDERAL DE VIÇOSA; ELIZABETE KEIKO TAKAHASHI, CENIBRA CELULOSE NIPO BRASILEIRA S.A; ORZENIL BONFIM DA SILVA JUNIOR, Cenargen; DARIO GRATTAPAGLIA, Cenargen. |
|
Título: |
Regional heritability mapping and genome-wide association identify loci for complex growth, wood and disease resistance traits in Eucalyptus. |
|
Ano de publicação: |
2017 |
|
Fonte/Imprenta: |
New Phytologist, v. 213, p. 1287-1300, 2017. |
|
DOI: |
10.1111/nph.14266 |
|
Idioma: |
Inglês |
|
Conteúdo: |
Although genome-wide association studies (GWAS) have provided valuable insights into the decoding of the relationships between sequence variation and complex phenotypes, they have explained little heritability. Regional heritability mapping (RHM) provides heritability estimates for genomic segments containing both common and rare allelic effects that individually contribute too little variance to be detected by GWAS. We carried out GWAS and RHM for seven growth, wood and disease resistance traits in a breeding population of 768 Eucalyptus hybrid trees using EuCHIP60K. Total genomic heritabilities accounted for large proportions (64?89%) of pedigree-based trait heritabilities, providing additional evidence that complex traits in eucalypts are controlled by many sequence variants across the frequency spectrum, each with small contributions to the phenotypic variance. RHM detected 26 quantitative trait loci (QTLs) encompassing 2191 single nucleotide polymorphisms (SNPs), whereas GWAS detected 13 single SNP?trait associations. RHM and GWAS QTLs individually explained 5?15% and 4?6% of the genomic heritability, respectively. RHM was superior to GWAS in capturing larger proportions of genomic heritability. Equated to previously mapped QTLs, our results highlighted genomic regions for further examination towards gene discovery. RHM-QTLs bearing a combination of common and rare variants could be useful enhancements to incorporate prior knowledge of the underlying genetic architecture in genomic prediction mode MenosAlthough genome-wide association studies (GWAS) have provided valuable insights into the decoding of the relationships between sequence variation and complex phenotypes, they have explained little heritability. Regional heritability mapping (RHM) provides heritability estimates for genomic segments containing both common and rare allelic effects that individually contribute too little variance to be detected by GWAS. We carried out GWAS and RHM for seven growth, wood and disease resistance traits in a breeding population of 768 Eucalyptus hybrid trees using EuCHIP60K. Total genomic heritabilities accounted for large proportions (64?89%) of pedigree-based trait heritabilities, providing additional evidence that complex traits in eucalypts are controlled by many sequence variants across the frequency spectrum, each with small contributions to the phenotypic variance. RHM detected 26 quantitative trait loci (QTLs) encompassing 2191 single nucleotide polymorphisms (SNPs), whereas GWAS detected 13 single SNP?trait associations. RHM and GWAS QTLs individually explained 5?15% and 4?6% of the genomic heritability, respectively. RHM was superior to GWAS in capturing larger proportions of genomic heritability. Equated to previously mapped QTLs, our results highlighted genomic regions for further examination towards gene discovery. RHM-QTLs bearing a combination of common and rare variants could be useful enhancements to incorporate prior knowledge of the underlying genetic architectur... Mostrar Tudo |
|
Thesaurus Nal: |
Eucalyptus. |
|
Categoria do assunto: |
-- |
|
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/159955/1/Resende-et-al-2017-New-Phytologist.pdf
|
|
Marc: |
LEADER 02237naa a2200217 a 4500
001 2074137
005 2023-03-31
008 2017 bl uuuu u00u1 u #d
024 7 $a10.1111/nph.14266$2DOI
100 1 $aRESENDE, R. T.
245 $aRegional heritability mapping and genome-wide association identify loci for complex growth, wood and disease resistance traits in Eucalyptus.$h[electronic resource]
260 $c2017
520 $aAlthough genome-wide association studies (GWAS) have provided valuable insights into the decoding of the relationships between sequence variation and complex phenotypes, they have explained little heritability. Regional heritability mapping (RHM) provides heritability estimates for genomic segments containing both common and rare allelic effects that individually contribute too little variance to be detected by GWAS. We carried out GWAS and RHM for seven growth, wood and disease resistance traits in a breeding population of 768 Eucalyptus hybrid trees using EuCHIP60K. Total genomic heritabilities accounted for large proportions (64?89%) of pedigree-based trait heritabilities, providing additional evidence that complex traits in eucalypts are controlled by many sequence variants across the frequency spectrum, each with small contributions to the phenotypic variance. RHM detected 26 quantitative trait loci (QTLs) encompassing 2191 single nucleotide polymorphisms (SNPs), whereas GWAS detected 13 single SNP?trait associations. RHM and GWAS QTLs individually explained 5?15% and 4?6% of the genomic heritability, respectively. RHM was superior to GWAS in capturing larger proportions of genomic heritability. Equated to previously mapped QTLs, our results highlighted genomic regions for further examination towards gene discovery. RHM-QTLs bearing a combination of common and rare variants could be useful enhancements to incorporate prior knowledge of the underlying genetic architecture in genomic prediction mode
650 $aEucalyptus
700 1 $aRESENDE, M. D. V. de
700 1 $aSILVA, F. F. S.
700 1 $aAZEVEDO, C. F. A.
700 1 $aTAKAHASHI, E. K. T.
700 1 $aSILVA JUNIOR, O. B. da
700 1 $aGRATTAPAGLIA, D.
773 $tNew Phytologist$gv. 213, p. 1287-1300, 2017.
Download
Esconder MarcMostrar Marc Completo |
|
Registro original: |
Embrapa Recursos Genéticos e Biotecnologia (CENARGEN) |
|
|
Biblioteca |
ID |
Origem |
Tipo/Formato |
Classificação |
Cutter |
Registro |
Volume |
Status |
URL |
Voltar
|
|
|
| Registros recuperados : 94 | |
| 21. |  | ALENCAR; SILVA JUNIOR, O. B. da; TOGAWA, R. C.; COSTA, M.; REVERS, L. F.; PAPPAS JUNIOR, G. J. SNP discovery in apple cultivars using next generation sequencing. BMC Proceedings, v. 5, Suppl 7,p. P42, 2011. Edição dos resumos do IUFRO Tree Biotechnology Conference 2011: From Genomes to Integration, 2011, Arraial d Ajuda, Bahia.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Recursos Genéticos e Biotecnologia. |
|    |
| 25. | | SILVA, P. I. T.; SILVA JUNIOR, O. B. da; RESENDE, L. V.; SOUSA, V. A. de; AGUIAR, A. V. de; GRATTAPAGLIA, D. A 3K Axiom SNP array from a transcriptomewide SNP resource sheds new light on the genetic diversity and structure of the iconic subtropical conifer tree Araucaria angustifolia (Bert.) Kuntze. PLoS ONE, v. 15, n. 8, e0230404, 2020.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
| Biblioteca(s): Embrapa Florestas; Embrapa Recursos Genéticos e Biotecnologia. |
|  |
| 26. | | PESSOA FILHO, M. A. C. de P.; SILVA, P. I. T.; RESENDE, L. V.; VIEIRA, E. A.; FALEIRO, F. G.; GRATTAPAGLIA, D.; SILVA JUNIOR, O. B. da. Application of the Axiom 3K SNP genotyping array in cassava breeding and genetics. In: PLANT AND ANIMAL GENOME CONFERENCE, 26., 2018, San Diego. Proceedings... Jersey City, NJ: Scherago International, 2018. PAG XXVI| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Recursos Genéticos e Biotecnologia. |
| |
| 27. | | PESSOA FILHO, M. A. C. de P.; SILVA, P. I. T.; RESENDE, L. V.; VIEIRA, E. A.; FALEIRO, F. G.; GRATTAPAGLIA, D.; SILVA JUNIOR, O. B. da. Application of the Axiom 3K SNP genotyping array in cassava breeding and genetics. In: PLANT AND ANIMAL GENOME CONFERENCE, 26., 2018, San Diego. Proceedings... Jersey City, NJ: Scherago International, 2018. PAG XXVI| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Cerrados. |
| |
| 28. | | SILVA JUNIOR, O. B. da; TOGAWA, R. C.; NOVAES, E.; FARIA, D. A. de; PAPPAS JUNIOR, G. J.; MATIAS, K.; GRATTAPAGLIA, D. Assessment of predicted assay functionality of Eucalyptus SNP derived from large interspecific collections of ESTs. In: IUFRO TREE BIOTECHNOLOGY CONFERENCE, 2009, Whislter. Abstracts. [S.l.]: IUFRO, 2009. p-52| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Recursos Genéticos e Biotecnologia. |
| |
| 29. | | LIMA, B. M.; SILVA JUNIOR, O. B. da; FARIA, D. A.; MAMANI, E. M. C.; PAPPAS JUNIOR, G. J.; GRATTAPAGLIA, D. Assessment of SNPs for linkage mapping in Eucalyptus: construction of a consensus SNP/microsatellite map from two unrelated pedigrees. BMC Proceedings, v. 5, suppl, P31, 2012. (Open access) Edição do Proceedings IUFRO Tree Biotechnology Conference, Arraial d?Ajuda, 2011.| Tipo: Artigo em Anais de Congresso |
| Biblioteca(s): Embrapa Recursos Genéticos e Biotecnologia. |
| |
| 30. | | MARTINS, A. M.; SILVA JUNIOR, O. B. da; NOVAES, E.; PAPPAS, M. de C. R.; FARIA, D. A. de; SCHMUTZ, J.; GRATTAPAGLIA, D.; PAPPAS JUNIOR, G. J. Allelic BAC sequencing in the highly heterozygous Eucalyptus genome reveals microcollinearity with variable patterns of haplotype diversity due to the movement of transposons. In: IUFRO TREE BIOTECHNOLOGY CONFERENCE, 2009, Whislter. Abstracts. [S.l.]: IUFRO, 2009. p. 51| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Recursos Genéticos e Biotecnologia. |
| |
| 31. | | SILVA JUNIOR, O. B. da; PESSOA FILHO, M. A. C. de P.; SA, M. E. L.; DEAL, R.; RAGOUSSIS, I.; GRATTAPAGLIA, D.; RECH FILHO, E. L. Coupling in-depth genome annotations with genome editing technology for harnessing genomic variation to promote precision breeding in tropical soybean. In: BRAZILIAN BIOTECHNOLOGY CONGRESS, 7.; BIOTECHNOLOGY IBERO-AMERICAN CONGRESS, 2., 2018, Brasília, DF. Proceedings... Brasília, DF: SBBiotec, 2018.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Recursos Genéticos e Biotecnologia. |
| |
| 32. | | SILVA JUNIOR, O. B. da; PESSOA FILHO, M. A. C. de P.; SA, M. E. L.; DEAL, R.; RAGOUSSIS, I.; GRATTAPAGLIA, D.; RECH FILHO, E. L. Coupling in-depth genome annotations with genome editing technology for harnessing genomic variation to promote precision breeding in tropical soybean. In: BRAZILIAN BIOTECHNOLOGY CONGRESS, 7.; BIOTECHNOLOGY IBERO-AMERICAN CONGRESS, 2., 2018, Brasília, DF. Proceedings... Brasília, DF: SBBiotec, 2018.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Cerrados. |
| |
| 33. | | SILVA JUNIOR, O. B. da; RESENDE, L. V.; VIDAL, R. F.; BORDALLO, P. N.; SILVA, P. I. T.; MELO, D. S.; TOGAWA, R. C.; GRATTAPAGLIA, D. A chromosome-scale assembly of the cashew tree genome: leveraging the combined power of PacBio, DNA-Chromatin Proximity Ligation and SNP linkage maps. In: PLANT AND ANIMAL GENOME CONFERENCE, 25., 2017, San Diego. [Abstracts...]. San Diego, CA: [s.n.], 2017. W354.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Recursos Genéticos e Biotecnologia. |
| |
| 34. | | PESSOA FILHO, M. A. C. de P.; SOUZA SOBRINHO, F. de; FRAGOSO, R. da R.; SILVA JUNIOR, O. B. da; FERREIRA, M. E. A draft genome assembly for the forage grass Urochloa ruziziensis based on single-molecule real-time sequencing. In: BRAZILIAN BIOTECHNOLOGY CONGRESS, 7.; BIOTECHNOLOGY IBERO-AMERICAN CONGRESS, 2., 2018, Brasília, DF. Proceedings... Brasília, DF: SBBiotec, 2018.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Recursos Genéticos e Biotecnologia. |
| |
| 35. | | PESSOA FILHO, M. A. C. de P.; SOUZA SOBRINHO, F. de; FRAGOSO, R. da R.; SILVA JUNIOR, O. B. da; FERREIRA, M. E. A draft genome assembly for the forage grass Urochloa ruziziensis based on single-molecule real-time sequencing. In: BRAZILIAN BIOTECHNOLOGY CONGRESS, 7.; BIOTECHNOLOGY IBERO-AMERICAN CONGRESS, 2., 2018, Brasília, DF. Proceedings... Brasília, DF: SBBiotec, 2018.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Cerrados. |
| |
| 36. | | SILVA JUNIOR, O. B. da; ROSADO, T. B.; LAVIOLA, B. G.; PAPPAS, M. de C. R.; PAPPAS JUNIOR, G. J.; GRATTAPAGLIA, D. Genome-wide SNP discovery from a pooled sample of accessions of the biofuel plant Jatropha curcas based on whole-transcriptome illumina resequencing. In: IUFRO TREE BIOTECHNOLOGY CONFERENCE, 2011, Arraial D'Ajuda, Brazil. From genomes do integration and delivery: extended abstracts proceedings. Brasília, DF: Embrapa, 2011. p. 151-152.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Recursos Genéticos e Biotecnologia. |
| |
| 37. | | SILVA JUNIOR, O. B. da; ROSADO, T. B.; LAVIOLA, B. G.; PAPPAS, M. de C. R.; PAPPAS JUNIOR, G. J.; GRATTAPAGLIA, D. Genome-wide SNP discovery from a pooled sample of accessions of the biofuel plant Jatropha curcas based on whole-transcriptome illumina resequencing. In: IUFRO TREE BIOTECHNOLOGY CONFERENCE, 2011, Arraial D'Ajuda, Brazil. From genomes do integration and delivery: extended abstracts proceedings. Brasília, DF: Embrapa, 2011. p. 151-152.| Tipo: Artigo em Anais de Congresso |
| Biblioteca(s): Embrapa Agroenergia. |
| |
| 40. | | PASSOS, M. A. N.; PAPPAS JUNIOR, G. J.; SILVA JUNIOR, O. B. da; EMEDIATO, F. L.; TEIXEIRA, C. C.; MILLER, R. N. G. Identificação e caracterização de components genéticos de resistência a Mycosphaerella musicola em Musa acuminata. In: CONGRESSO BRASILEIRO DE FITOPATOLOGIA, 45., 2012, Manaus. Fito 2012. Tropical Plant Pathology, Brasília, DF, v. 37, 2012. Suplemento. Resumo 470. 1 CD-ROM.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Recursos Genéticos e Biotecnologia. |
| |
| Registros recuperados : 94 | |
|
| Nenhum registro encontrado para a expressão de busca informada. |
|
|
