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Registro Completo |
Biblioteca(s): |
Embrapa Gado de Leite. |
Data corrente: |
21/08/2023 |
Data da última atualização: |
21/08/2023 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Autoria: |
OTTO, P. I.; GUIMARÃES, S. E. F.; CALUS, M. P. L.; VANDENPLAS, J.; MACHADO, M. A.; PANETTO, J. C. do C.; SILVA, M. V. G. B. |
Afiliação: |
PAMELA I. OTTO, Universidade Federal de Viçosa; SIMONE E. F. GUIMARÃES, Universidade Federal de Viçosa; MARIO P. L. CALUS, Wageningen University & Research; JEREMIE VANDENPLAS, Wageningen University & Research; MARCO ANTONIO MACHADO, CNPGL; JOAO CLAUDIO DO CARMO PANETTO, CNPGL; MARCOS VINICIUS GUALBERTO B SILVA, CNPGL. |
Título: |
Single-step genome-wide association studies (GWAS) and post-GWAS analyses to identify genomic regions and candidate genes for milk yield in Brazilian Girolando cattle. |
Ano de publicação: |
2020 |
Fonte/Imprenta: |
Journal of Dairy Science, v. 103, n. 11, p. 10347-10360, 2020. |
DOI: |
https://doi.org/10.3168/jds.2019-17890 |
Idioma: |
Inglês |
Conteúdo: |
Milk production is economically important to the Brazilian agribusiness, and the majority of the country's milk production derives from Girolando (Gir × Holstein) cows. This study aimed to identify quantitative trait loci (QTL) and candidate genes associated with 305-d milk yield (305MY) in Girolando cattle. In addition, we investigated the SNP-specific variances for Holstein and Gir breeds of origin within the sequence of candidate genes. A single-step genomic BLUP procedure was used to identify QTL associated with 305MY, and the most likely candidate genes were identified through follow-up analyses. Genomic breeding values specific for Holstein and Gir were estimated in the Girolando animals using a model that uses breed-specific partial relationship matrices, which were converted to breed of origin SNP effects. Differences between breed of origin were evaluated by comparing estimated SNP variances between breeds. From 10 genome regions explaining most additive genetic variance for 305MY in Girolando cattle, 7 candidate genes were identified on chromosomes 1, 4, 6, and 26. Within the sequence of these 7 candidate genes, Gir breed of origin SNP alleles showed the highest genetic variance. These results indicated QTL regions that could be further explored in genomic selection panels and which may also help in understanding the gene mechanisms involved in milk production in the Girolando breed. |
Thesagro: |
Gado Gir; Gado Leiteiro; Gene; Produção Leiteira. |
Categoria do assunto: |
L Ciência Animal e Produtos de Origem Animal |
Marc: |
LEADER 02266naa a2200253 a 4500 001 2156012 005 2023-08-21 008 2020 bl uuuu u00u1 u #d 024 7 $ahttps://doi.org/10.3168/jds.2019-17890$2DOI 100 1 $aOTTO, P. I. 245 $aSingle-step genome-wide association studies (GWAS) and post-GWAS analyses to identify genomic regions and candidate genes for milk yield in Brazilian Girolando cattle.$h[electronic resource] 260 $c2020 520 $aMilk production is economically important to the Brazilian agribusiness, and the majority of the country's milk production derives from Girolando (Gir × Holstein) cows. This study aimed to identify quantitative trait loci (QTL) and candidate genes associated with 305-d milk yield (305MY) in Girolando cattle. In addition, we investigated the SNP-specific variances for Holstein and Gir breeds of origin within the sequence of candidate genes. A single-step genomic BLUP procedure was used to identify QTL associated with 305MY, and the most likely candidate genes were identified through follow-up analyses. Genomic breeding values specific for Holstein and Gir were estimated in the Girolando animals using a model that uses breed-specific partial relationship matrices, which were converted to breed of origin SNP effects. Differences between breed of origin were evaluated by comparing estimated SNP variances between breeds. From 10 genome regions explaining most additive genetic variance for 305MY in Girolando cattle, 7 candidate genes were identified on chromosomes 1, 4, 6, and 26. Within the sequence of these 7 candidate genes, Gir breed of origin SNP alleles showed the highest genetic variance. These results indicated QTL regions that could be further explored in genomic selection panels and which may also help in understanding the gene mechanisms involved in milk production in the Girolando breed. 650 $aGado Gir 650 $aGado Leiteiro 650 $aGene 650 $aProdução Leiteira 700 1 $aGUIMARÃES, S. E. F. 700 1 $aCALUS, M. P. L. 700 1 $aVANDENPLAS, J. 700 1 $aMACHADO, M. A. 700 1 $aPANETTO, J. C. do C. 700 1 $aSILVA, M. V. G. B. 773 $tJournal of Dairy Science$gv. 103, n. 11, p. 10347-10360, 2020.
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202. | | ANDRADE, L. G. D.; MUNIZ, M. N. M.; TAGLIATTI, R. F.; GUEDES, E.; SILVA, M. V. G. B.; ARBEX, W. A. Organizing of data warehouse using perl and DBMS for genotyping data. In: INTERNATIONAL CONFERENCE OF THE BRAZILIAN ASSOCIATION FOR BIOINFORMATICS AND COMPUTATIONAL BIOLOGY, 6., 2010, Ouro Preto. Abstracts... [S.l.: s.n.], 2010.Tipo: Resumo em Anais de Congresso |
Biblioteca(s): Embrapa Gado de Leite. |
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203. | | STUMPF, M. T.; SILVA, M. V. G. B.; PIMENTEL, C. M. M.; FISCHER, V.; KOLLING, G. J.; ALFONSO, E. P. M.; DALTRO, D. dos S.; DALCIN, V. C. Parâmetros fisiológicos e sanguíneos de vacas lactantes com diferentes constituições genéticas em relação a elevados índices de temperatura e umidade. In: CONGRESSO INTERNACIONAL DO LEITE, 13., 2015, Porto Alegre. Anais... Juiz de Fora: Embrapa Gado de Leite, 2015. 4 p.Tipo: Artigo em Anais de Congresso |
Biblioteca(s): Embrapa Gado de Leite. |
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204. | | BÖCK, M. J.; SILVA, M. V. G. B.; PANETTO, J. C. do C.; MARTINS, M. F.; NEGRI, R.; OTTO, P. I. Padrão de ancestralidade nas raças Holandesa, Jersey e Pardo-Suiça. In: SIMPÓSIO INTERNACIONAL DE BOVINOCULTURA LEITEIRA, 9., 2023, Viçosa, MG. Anais... Viçosa, MG: Universidade Federal de Viçosa, 2023. p. 476-478.Tipo: Artigo em Anais de Congresso |
Biblioteca(s): Embrapa Gado de Leite. |
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205. | | FOYE-JACKSON, O. T.; LONG, J. A.; BAKST, M. R.; BLOMBERG, L. A.; AKUFFO, V. G.; SILVA, M. V. G. B.; GUTHRIE, H. D.; McMURTRY, J. P. Oviductal expression of avidin, avidin-related protein-2, and progesterone receptor in turkey hens in relation to sperm storage: effects of oviduct tissue type, sperm presence, and turkey line. Poultry Science, v. 90, n. 7, p. 1539-1547, 2011.Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 2 |
Biblioteca(s): Embrapa Gado de Leite. |
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219. | | ALFONZO, E. P.; SILVA, M. V. G. B.; SANTOS, D. D. dos; STUMPF, M. T.; DALCIN, V. C.; KOLLING, G.; FISCHER, V.; McMANUS, C. M. Relationship between physical attributes and heat stress in dairy cattle from different genetic groups. International Journal of Biometeorology, v. 60, n. 2, p. 245-353, 2015.Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 2 |
Biblioteca(s): Embrapa Gado de Leite. |
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220. | | IANELLA, P.; CAMPOS, T. A. de; PAIVA, S. R.; GUIMARAES, M. F. M.; SILVA, M. V. G. B.; CAETANO, A. R. Prospecção de Polimorfismos de Base Única (SNPs) no gene k-caseina (KCN) na raça Girolando. In: REUNIÃO ANUAL DA SOCIEDADE BRASILEIRA DE ZOOTECNIA, 47., 2010, Salvador. Empreendedorismo e progresso científico na zootecnia brasileira: anais. Viçosa, MG: Sociedade Brasileira de Zootecnia, 2010. 3 p.Tipo: Artigo em Anais de Congresso |
Biblioteca(s): Embrapa Gado de Leite; Embrapa Recursos Genéticos e Biotecnologia. |
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Registros recuperados : 535 | |
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