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 | Acesso ao texto completo restrito à biblioteca da Embrapa Mandioca e Fruticultura. Para informações adicionais entre em contato com cnpmf.biblioteca@embrapa.br. |
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Registro Completo |
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Biblioteca(s): |
Embrapa Mandioca e Fruticultura. |
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Data corrente: |
24/10/2012 |
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Data da última atualização: |
25/05/2023 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
HORA JUNIOR, B. T. da; POLONI, J. de F.; LOPES, M. A.; DIAS, C. V.; GRAMACHO, K. P.; SCHUSTER, I.; SABAU, X.; CASCARDO, J. C. de M.; DI MAURO, S. M. Z.; GESTEIRA, A. da S.; BONATTO, D.; MICHELI, F. |
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Afiliação: |
BRAZ TAVARES DA HORA JUNIOR, UESC; JOICE DE FARIA POLONI, PUCRS; MAÍZA ALVES LOPES, UESC; CRISTIANO VILLELA DIAS, UESC; KARINA PERES GRAMACHO, CEPLAC; IVAN SCHUSTER, COODETEC; XAVIER SABAU, CIRAD; JÚLIO CÉZAR DE MATTOS CASCARDO, UESC; SÔNIA MARLI ZINGARETTI DI MAURO, UNESP; ABELMON DA SILVA GESTEIRA, CNPMF; DIEGO BONATTO, CEPLAC; FABIENNE MICHELI, UESC. |
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Título: |
Transcriptomics and systems biology analysis in identification of specific pathways involved in cacao resistance and susceptibility to witches. |
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Ano de publicação: |
2012 |
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Fonte/Imprenta: |
Molecular BioSystems, n.8, p. 1507-1519, 2012 |
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ISSN: |
1742-206X |
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Idioma: |
Inglês |
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Conteúdo: |
This study reports on expression analysis associated with molecular systems biology of cacao-Moniliophthora perniciosa interaction. Gene expression data were obtained for two cacao genotypes (TSH1188, resistant; Catongo, susceptible) challenged or not with the fungus M. perniciosa and collected at three time points through disease. Using expression analysis, we identified 154 and 227 genes that are differentially expressed in TSH1188 and Catongo, respectively. The expression of some of these genes was confirmed by RT-qPCR. Physical protein?protein interaction (PPPI) networks of Arabidopsis thaliana orthologous proteins corresponding to resistant and susceptible interactions were obtained followed by cluster and gene ontology analyses. The integrated analysis of gene expression and systems biology allowed designing a general scheme of major mechanisms associated with witches? broom disease resistance/susceptibility. In this sense, the TSH1188 cultivar shows strong production of ROS and elicitors at the beginning of the interaction with M. perniciosa followed by resistance signal propagation and ROS detoxification. On the other hand, the Catongo genotype displays defense mechanisms that include the synthesis of some defense molecules but without success in regards to elimination of the fungus. This phase is followed by the activation of protein metabolism which is achieved with the production of proteasome associated with autophagy as a precursor mechanism of PCD. This work also identifies candidate genes for further functional studies and for genetic mapping and marker assisted selection. MenosThis study reports on expression analysis associated with molecular systems biology of cacao-Moniliophthora perniciosa interaction. Gene expression data were obtained for two cacao genotypes (TSH1188, resistant; Catongo, susceptible) challenged or not with the fungus M. perniciosa and collected at three time points through disease. Using expression analysis, we identified 154 and 227 genes that are differentially expressed in TSH1188 and Catongo, respectively. The expression of some of these genes was confirmed by RT-qPCR. Physical protein?protein interaction (PPPI) networks of Arabidopsis thaliana orthologous proteins corresponding to resistant and susceptible interactions were obtained followed by cluster and gene ontology analyses. The integrated analysis of gene expression and systems biology allowed designing a general scheme of major mechanisms associated with witches? broom disease resistance/susceptibility. In this sense, the TSH1188 cultivar shows strong production of ROS and elicitors at the beginning of the interaction with M. perniciosa followed by resistance signal propagation and ROS detoxification. On the other hand, the Catongo genotype displays defense mechanisms that include the synthesis of some defense molecules but without success in regards to elimination of the fungus. This phase is followed by the activation of protein metabolism which is achieved with the production of proteasome associated with autophagy as a precursor mechanism of PCD. This work al... Mostrar Tudo |
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Palavras-Chave: |
Molecular systems biology. |
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Thesagro: |
Cação. |
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Categoria do assunto: |
X Pesquisa, Tecnologia e Engenharia |
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Marc: |
LEADER 02490naa a2200289 a 4500
001 1937900
005 2023-05-25
008 2012 bl uuuu u00u1 u #d
022 $a1742-206X
100 1 $aHORA JUNIOR, B. T. da
245 $aTranscriptomics and systems biology analysis in identification of specific pathways involved in cacao resistance and susceptibility to witches.$h[electronic resource]
260 $c2012
520 $aThis study reports on expression analysis associated with molecular systems biology of cacao-Moniliophthora perniciosa interaction. Gene expression data were obtained for two cacao genotypes (TSH1188, resistant; Catongo, susceptible) challenged or not with the fungus M. perniciosa and collected at three time points through disease. Using expression analysis, we identified 154 and 227 genes that are differentially expressed in TSH1188 and Catongo, respectively. The expression of some of these genes was confirmed by RT-qPCR. Physical protein?protein interaction (PPPI) networks of Arabidopsis thaliana orthologous proteins corresponding to resistant and susceptible interactions were obtained followed by cluster and gene ontology analyses. The integrated analysis of gene expression and systems biology allowed designing a general scheme of major mechanisms associated with witches? broom disease resistance/susceptibility. In this sense, the TSH1188 cultivar shows strong production of ROS and elicitors at the beginning of the interaction with M. perniciosa followed by resistance signal propagation and ROS detoxification. On the other hand, the Catongo genotype displays defense mechanisms that include the synthesis of some defense molecules but without success in regards to elimination of the fungus. This phase is followed by the activation of protein metabolism which is achieved with the production of proteasome associated with autophagy as a precursor mechanism of PCD. This work also identifies candidate genes for further functional studies and for genetic mapping and marker assisted selection.
650 $aCação
653 $aMolecular systems biology
700 1 $aPOLONI, J. de F.
700 1 $aLOPES, M. A.
700 1 $aDIAS, C. V.
700 1 $aGRAMACHO, K. P.
700 1 $aSCHUSTER, I.
700 1 $aSABAU, X.
700 1 $aCASCARDO, J. C. de M.
700 1 $aDI MAURO, S. M. Z.
700 1 $aGESTEIRA, A. da S.
700 1 $aBONATTO, D.
700 1 $aMICHELI, F.
773 $tMolecular BioSystems$gn.8, p. 1507-1519, 2012
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Registro original: |
Embrapa Mandioca e Fruticultura (CNPMF) |
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Registro Completo
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Biblioteca(s): |
Embrapa Unidades Centrais. |
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Data corrente: |
15/08/2016 |
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Data da última atualização: |
15/08/2016 |
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Autoria: |
MOTTA, R. G.; MOTTA, I. G.; MARTINEZ, A. C.; SILVA, A. V. da; PAES, A. C.; MARTINS, L. S. A.; SILVA, R. C. da; RIBEIRO, M. G. |
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Afiliação: |
RODRIGO GARCIA MOTTA, FMVZ/UNESP; IGOR GARCIA MOTTA, UNICENTRO; ANTONIO CAMPANHA MARTINEZ, UEM; ARISTEU VIEIRA DA SILVA, UEFS; ANTONIO CARLOS PAES, FMVZ/UNESP; LORRAYNE SOUZA ARAUJO MARTINS, UniRV; RODRIGO COSTA DA SILVA, Mississippi State university; MARCIO GARCIA RIBEIRO, FMVZ/UNESP. |
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Título: |
Unusual caudal vena cava thrombosis in a cow, secondary to Trueperella (Arcanobacterium) pyogenes infection. |
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Ano de publicação: |
2016 |
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Fonte/Imprenta: |
Pesquisa Veterinária Brasileira, Brasília, DF, v.36, n. 7, p. 587-590, jul. 2016. |
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Idioma: |
Inglês |
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Conteúdo: |
The caudal vena cava thrombosis, or pulmonary thromboembolism, in cattle is correlated with lactic acidosis, caused by diets rich in grains and highly fermentable, associated or not to septic situations, used in feedlots of beef or high-producing dairy cattle. This paper reports an unusual caudal vena cava thrombosis in a cow, secondary to Trueperella (Arcanobacterium) pyogenes infection, resulting in reduced milk production, anorexia, pale mucous membranes, ruminal atony, sternal decubitus and autoauscultation position. The heart was enlarged at necropsy, presence of clots distributed along the thoracic cavity, adherence between lung and pleura, abscesses, emphysema, petechiae, suffusions and ecchymosis in lungs, thickening of the caudal vena cava wall, hepatomegaly with chronic passive congestion (?nutmeg? aspect), and rumenitis. In lab, the actinomycete Trueperella (Arcanobacterium) pyogenes was isolated from liver and lung samples, probably resulting through dissemination of the bacteria of the rumen content, what reaffirms the opportunistic behavior of this actinomycete. |
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Palavras-Chave: |
Abscesses; Abscessos; Thromboembolism; Tromboembolismo. |
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Thesagro: |
Acidose; Ruminante. |
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Thesaurus NAL: |
Acidosis; Arcanobacterium pyogenes; Ruminants. |
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Categoria do assunto: |
-- |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/146353/1/Unusual-caudal-vena-cava.pdf
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Marc: |
LEADER 01982naa a2200313 a 4500
001 2050848
005 2016-08-15
008 2016 bl uuuu u00u1 u #d
100 1 $aMOTTA, R. G.
245 $aUnusual caudal vena cava thrombosis in a cow, secondary to Trueperella (Arcanobacterium) pyogenes infection.
260 $c2016
520 $aThe caudal vena cava thrombosis, or pulmonary thromboembolism, in cattle is correlated with lactic acidosis, caused by diets rich in grains and highly fermentable, associated or not to septic situations, used in feedlots of beef or high-producing dairy cattle. This paper reports an unusual caudal vena cava thrombosis in a cow, secondary to Trueperella (Arcanobacterium) pyogenes infection, resulting in reduced milk production, anorexia, pale mucous membranes, ruminal atony, sternal decubitus and autoauscultation position. The heart was enlarged at necropsy, presence of clots distributed along the thoracic cavity, adherence between lung and pleura, abscesses, emphysema, petechiae, suffusions and ecchymosis in lungs, thickening of the caudal vena cava wall, hepatomegaly with chronic passive congestion (?nutmeg? aspect), and rumenitis. In lab, the actinomycete Trueperella (Arcanobacterium) pyogenes was isolated from liver and lung samples, probably resulting through dissemination of the bacteria of the rumen content, what reaffirms the opportunistic behavior of this actinomycete.
650 $aAcidosis
650 $aArcanobacterium pyogenes
650 $aRuminants
650 $aAcidose
650 $aRuminante
653 $aAbscesses
653 $aAbscessos
653 $aThromboembolism
653 $aTromboembolismo
700 1 $aMOTTA, I. G.
700 1 $aMARTINEZ, A. C.
700 1 $aSILVA, A. V. da
700 1 $aPAES, A. C.
700 1 $aMARTINS, L. S. A.
700 1 $aSILVA, R. C. da
700 1 $aRIBEIRO, M. G.
773 $tPesquisa Veterinária Brasileira, Brasília, DF$gv.36, n. 7, p. 587-590, jul. 2016.
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Embrapa Unidades Centrais (AI-SEDE) |
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