Data/hora: 08/06/2024 14:34:26

Biblioteca(s): 	Embrapa Agroindústria de Alimentos.	
Data corrente: 	27/06/2013	
Data da última atualização: 	29/02/2016	
Autoria: 	KAIPPERT, V. C.; UEHARA, S. K.; D'ANDREA, C. L.; NOGUEIRA, J.; LAGO, M. F. do; LOPES, M. C. O. dos S.; OLIVEIRA, E. M. M.; ROSADO, E. L.	
Afiliação: 	VANESSA CHAIA KAIPPERT, UFRJ; SOFIA KIMI UEHARA, UFRJ; CARLA LIMA D'ANDREA, UFRJ; JULIANA NOGUEIRA, UFRJ; MÁRCIA FÓFANO DO LAGO, UFRJ; MARCELLY CUNHA OLIVEIRA DOS SANTOS, UFRJ; EDNA MARIA MORAIS OLIVEIRA, CTAA; ELIANE LOPES ROSADO, UFRJ.	
Título: 	Influence of the body mass and visceral adiposity on glucose metabolism in obese women with Pro12Pro genotype in PPARgamma2 gene.	
Ano de publicação: 	2013	
Fonte/Imprenta: 	Nutrición Hospitalaria, Madrid, v. 28, n. 3, p. 694-700, 2013.	
DOI: 	10.3305/nh.2013.28.3.6372	
Idioma: 	Inglês	
Conteúdo: 	Introduction: Glucose metabolism may be altered in obesity and genotype for PPAR 2 can influence this variable. Objective: To evaluate the influence of body mass (BM) and visceral adiposity (VA) in glucose metabolism in morbid obese women with Pro12Pro genotype. Methods: Were selected 25 morbidly obese women. Groups were formed according to body mass index (BMI) [G1: 40-45 kg/m2 (n = 17); G2: > 45 kg/m2 (n = 8)]. Anthropometric, glycemia and insulinemia assessments (fasting, 60 and 120 minutes after high polyunsaturated fatty acids meal) were carried out. The insulin resistance (IR) and insulin sensitivity (IS) were assessed by HOMA-IR and QUICKI respectively. Results: G2 had higher BMI and waist circumference, compared to G1, impaired fasting glucose, low IS and higher IR. The postprandial glucose was normal, but there was a higher insulin peak one hour after the meal in G2. Conclusion: Increased BM and VA were associated with worse glucose metabolism suggesting metabolic differences between morbid obese with Pro12Pro genotype.	
Palavras-Chave: 	Índice de massa corporal; Metabolismo da glicose; PPARgamma; Resistência à insulina.	
Thesagro: 	Obesidade.	
Categoria do assunto: 	X Pesquisa, Tecnologia e Engenharia	
URL: 	http://ainfo.cnptia.embrapa.br/digital/bitstream/item/84902/1/2013-005.pdf	
Registro original: 	Embrapa Agroindústria de Alimentos (CTAA)	
Exemplares: 	CTAA - (11817-1) - UPC - AP - PP - 2013/005 -  - 2013.00005 - DIS