Data/hora: 07/06/2024 08:25:22

Biblioteca(s): | Embrapa Instrumentação.
Data corrente: | 11/01/2024
Data da última atualização: | 11/01/2024
Autoria: | SANTOS, F. V. dos; SIQUEIRA, R. L.; RAMOS, L. de M.; YOSHIOKA, S. A.; BRANCIFORTI, M. C.; CORREA, D. S.
Afiliação: | University of São Paulo; Federal University of Sao Carlos; University of Sao Paulo; University of Sao Paulo; University of Sao Paulo; DANIEL SOUZA CORREA, CNPDIA.
Título: | Silk fibroin-derived electrospun materials for biomedical applications: A review.
Ano de publicação: | 2024
Fonte/Imprenta: | International Journal of Biological Macromolecules, v. 254, 127641, 2024.
Páginas: | 34 p.
ISSN: | 0141-8130
DOI: | https://doi.org/10.1016/j.ijbiomac.2023.127641
Idioma: | Inglês
Conteúdo: | Electrospinning is a versatile technique for fabricating polymeric fibers with diameters ranging from micro- to nanoscale, exhibiting multiple morphologies and arrangements. By combining silk fibroin (SF) with synthetic and/or natural polymers, electrospun materials with outstanding biological, chemical, electrical, physical, mechanical, and optical properties can be achieved, fulfilling the evolving biomedical demands. This review highlights the remarkable versatility of SF-derived electrospun materials, specifically focusing on their application in tissue regeneration (including cartilage, cornea, nerves, blood vessels, bones, and skin), disease treatment (such as cancer and diabetes), and the development of controlled drug delivery systems. Additionally, we explore the potential future trends in utilizing these nanofibrous materials for creating intelligent biomaterials, incorporating biosensors and wearable sensors for monitoring human health, and also discuss the bottlenecks for its widespread use. This comprehensive overview illuminates the significant impact and exciting prospects of SF-derived electrospun materials in advancing biomedical research and applications.
Palavras-Chave: | Biomaterials; Electrospinning; Regenerative medicine; Silk fibroin.
Categoria do assunto: | --
Registro original: | Embrapa Instrumentação (CNPDIA)
Exemplares: | CNPDIA - (18368-1) - UPC - AP - DD - PROCI.24/09 -  - 2024/09 - DIS