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Registro Completo |
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Biblioteca(s): |
Embrapa Milho e Sorgo. |
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Data corrente: |
09/09/2014 |
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Data da última atualização: |
23/05/2017 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
GAZAFFI, R.; MARGARIDO, G. R. A.; PASTINA, M. M.; MOLLINARI, M.; GARCIA, A. A. F. |
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Afiliação: |
MARIA MARTA PASTINA, CNPMS. |
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Título: |
A model for quantitative trait loci mapping. |
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Ano de publicação: |
2014 |
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Fonte/Imprenta: |
Tree Genetics & Genomes, v. 10, p. 791-801, 2014. |
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DOI: |
10.1007/s11295-013-0664-2 |
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Idioma: |
Inglês |
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Conteúdo: |
Quantitative trait loci (QTL) mapping is an important approach for the study of the genetic architecture of quantitative traits. For perennial species, inbred lines cannot be obtained due to inbreed depression and a long juvenile period. Instead, linkage mapping can be performed by using a full-sib progeny. This creates a complex scenario because both markers and QTL alleles can have different segregation patterns as well as different linkage phases between them. We present a two-step method for QTL mapping using full-sib progeny based on composite interval mapping (i.e., interval mapping with cofactors), considering an integrated genetic map with markers with different segregation patterns and conditional probabilities obtained by a multipoint approach. The model is based on three orthogonal contrasts to estimate the additive effect (one in each parent) and dominance effect. These estimatives are obtained using the EM algorithm. In the first step, the genome is scanned to detect QTL. After, segregation pattern and linkage phases between QTL and markers are estimated. A simulated example is presented to validate the methodology. In general, the new model is more effective than existing approaches, because it can reveal QTL present in a full-sib progeny that segregates in any pattern present and can also identify dominance effects. Also, the inclusion of cofactors provided more statistical power for QTL mapping. |
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Palavras-Chave: |
Arquitetura genética. |
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Thesagro: |
Genética; Progênie. |
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Categoria do assunto: |
-- |
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Marc: |
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024 7 $a10.1007/s11295-013-0664-2$2DOI
100 1 $aGAZAFFI, R.
245 $aA model for quantitative trait loci mapping.$h[electronic resource]
260 $c2014
520 $aQuantitative trait loci (QTL) mapping is an important approach for the study of the genetic architecture of quantitative traits. For perennial species, inbred lines cannot be obtained due to inbreed depression and a long juvenile period. Instead, linkage mapping can be performed by using a full-sib progeny. This creates a complex scenario because both markers and QTL alleles can have different segregation patterns as well as different linkage phases between them. We present a two-step method for QTL mapping using full-sib progeny based on composite interval mapping (i.e., interval mapping with cofactors), considering an integrated genetic map with markers with different segregation patterns and conditional probabilities obtained by a multipoint approach. The model is based on three orthogonal contrasts to estimate the additive effect (one in each parent) and dominance effect. These estimatives are obtained using the EM algorithm. In the first step, the genome is scanned to detect QTL. After, segregation pattern and linkage phases between QTL and markers are estimated. A simulated example is presented to validate the methodology. In general, the new model is more effective than existing approaches, because it can reveal QTL present in a full-sib progeny that segregates in any pattern present and can also identify dominance effects. Also, the inclusion of cofactors provided more statistical power for QTL mapping.
650 $aGenética
650 $aProgênie
653 $aArquitetura genética
700 1 $aMARGARIDO, G. R. A.
700 1 $aPASTINA, M. M.
700 1 $aMOLLINARI, M.
700 1 $aGARCIA, A. A. F.
773 $tTree Genetics & Genomes$gv. 10, p. 791-801, 2014.
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Embrapa Milho e Sorgo (CNPMS) |
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| 47. |  | MUNOZ, A. E. P.; FLORES, R. V.; PEDROZA FILHO, M. X.; RODRIGUES, A. P.; MATAVELI, M.; BARROSO, R. Economic viability of aquaculture production in Brazil. In: FENACAM & LACQUA/SARA (WAS)'15.; LATIN AMERICAN & CARIBBEAN AQUACULTURE 15.; SOUTH AMERICAN REGIONAL AQUACULTURE 15.; INTERNATIONAL SHRIMP FARMING SYMPOSIUM, 12.; INTERNATIONAL ACQUACULTURE TRADE SHOW, 12.; INTERNATIONAL AQUACULTURE SYMPOSIUM, 9.; TILAPIA ECONOMIC FORUM, 3., 2015, Fortaleza. Abstracts... Fortaleza: ABCC: World Aquaculture Society, 2015. p. 437.| Tipo: Resumo em Anais de Congresso |
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| 50. | | MUNOZ, A. E. P.; FLORES, R. M. V.; PEDROZA FILHO, M. X.; BARROSO, R. M.; MATAVELI, M.; REZENDE, F. P. Piscicultores e demais agentes da cadeia produtiva discutem os custos de produção da tilápia no açude Castanhão, Jaguaribara, Ceará. Palmas: Embrapa Pesca e Aquicultura, 2015. 6 p. (Informativo Campo Futuro, 13).| Tipo: Folder/Folheto/Cartilha |
| Biblioteca(s): Embrapa Pesca e Aquicultura. |
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| 59. | | PEDROZA FILHO, M. X.; RODRIGUES, A. P. O.; REZENDE, F. P.; FLORES, R. M. V.; MUNOZ, A. E. P.; BARROSO, R. M. Analysis of a participatory approach for collection of economic data in aquaculture systems at farm level in Brazil. Custos e @gronegócio on line, Recife, v. 13, n. 1, p. 294-314, jan./mar. 2017.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 2 |
| Biblioteca(s): Embrapa Pesca e Aquicultura. |
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| Registros recuperados : 78 | |
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