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Registro Completo |
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Biblioteca(s): |
Embrapa Meio Ambiente. |
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Data corrente: |
28/07/2020 |
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Data da última atualização: |
28/07/2020 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
DELCORSO, M. C.; PAIVA, P. P. de; GRIGOLETO, M. R. P.; QUEIROZ, S. C. do N. de; COLLARES-BUZATO, C. B.; ARANA, S. |
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Afiliação: |
MARIANA CRUZ DELCORSO, IB-UNICAMP; PAULA PEREIRA DE PAIVA, IB-UNICAMP; MARCELA REGINA PAGANUCHI GRIGOLETO, IB-UNICAMP; SONIA CLAUDIA DO N DE QUEIROZ, CNPMA; CARLA BEATRIZ COLLARES-BUZATO, IB-UNICAMP; SARAH ARANA, IB-UNICAMP. |
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Título: |
Effects of sublethal and realistic concentrations of the commercial herbicide atrazine in Pacu (Piaractus mesopotamicus): long-term exposure and recovery assays. |
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Ano de publicação: |
2020 |
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Fonte/Imprenta: |
Veterinary World, v. 13, n. 1, p. 147-159, 2020. |
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DOI: |
www.doi.org/10.14202/vetworld.2020.147-159 |
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Idioma: |
Inglês |
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Conteúdo: |
Abstract: Background and Aim: The commercial formulations of the herbicide atrazine (cATZ) are widely employed in Brazilian agriculture, and, as a consequence, ATZ has been found at levels above that established by law in the river basins in Brazil. Although the toxicity of ATZ in fish is well documented, there are few studies on the recovery capacity after cATZ exposure. This work aimed to evaluate, using several biomarkers, the toxic effects of long-term exposure to the sublethal (3.57 mg/L) and nonlethal realistic (3.00 ?g/L) cATZ concentrations followed by a recovery assay, in fingerlings of a Brazilian teleost, the Piaractus mesopotamicus (pacu). Materials and Methods: Pacu fingerlings were housed in glass tanks and divided into the following experimental groups (two tanks/group): Exposure control = EC, recovery control = RC, the sublethal groups exposed to 3.57 mg/L of cATZ, (sublethal exposure group = SLE and sublethal recovery group = SLR) and the nonlethal groups treated with 3.00 μg/L of cATZ (nonlethal exposure group = NLE and nonlethal recovery group = NLR). The exposure assay was semi-static with a duration of 30 days and the recovery assay (after cATZ withdrawal) lasted 14 days. Several biomarkers were evaluated in fingerlings from all groups: The swimming behavior, the body weight gain, the micronucleus formation and nuclear alterations in erythrocytes, and the hepatic and renal histopathology analyzed by qualitative and semi-quantitative morphological methods (using light and electron microscopy). Results: No significant difference in weight gain was observed among the groups after the exposure and recovery assays. The sublethal exposure induced impaired swimming movements, significant histopathological alterations, including necrosis in the liver and kidney, and a significant increase in the frequency of micronuclei in erythrocytes. The nonlethal exposure induced only subtle histopathological changes in the liver and kidney. After recovery assay, no genotoxic alteration was noted in pacu exposed to sublethal concentration, while the cATZ-induced kidney damage was partially reversed but not the hepatic injury. Conclusion: cATZ exhibits long-term toxic effects on pacu, even at relatively low concentrations, affecting mainly the liver and the kidney, and the effects of sublethal concentration are only partially reversed after cATZ withdrawal. MenosAbstract: Background and Aim: The commercial formulations of the herbicide atrazine (cATZ) are widely employed in Brazilian agriculture, and, as a consequence, ATZ has been found at levels above that established by law in the river basins in Brazil. Although the toxicity of ATZ in fish is well documented, there are few studies on the recovery capacity after cATZ exposure. This work aimed to evaluate, using several biomarkers, the toxic effects of long-term exposure to the sublethal (3.57 mg/L) and nonlethal realistic (3.00 ?g/L) cATZ concentrations followed by a recovery assay, in fingerlings of a Brazilian teleost, the Piaractus mesopotamicus (pacu). Materials and Methods: Pacu fingerlings were housed in glass tanks and divided into the following experimental groups (two tanks/group): Exposure control = EC, recovery control = RC, the sublethal groups exposed to 3.57 mg/L of cATZ, (sublethal exposure group = SLE and sublethal recovery group = SLR) and the nonlethal groups treated with 3.00 μg/L of cATZ (nonlethal exposure group = NLE and nonlethal recovery group = NLR). The exposure assay was semi-static with a duration of 30 days and the recovery assay (after cATZ withdrawal) lasted 14 days. Several biomarkers were evaluated in fingerlings from all groups: The swimming behavior, the body weight gain, the micronucleus formation and nuclear alterations in erythrocytes, and the hepatic and renal histopathology analyzed by qualitative and semi-quantitative morphological me... Mostrar Tudo |
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Palavras-Chave: |
Brazilian ichthyofauna; Kidney lesions; Liver lesions; Recovery assay; Toxicidade. |
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Thesagro: |
Herbicida; Pacu; Poluição da Água; Toxidez. |
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Thesaurus Nal: |
Atrazine; Genotoxicity; Herbicides; Histopathology; Piaractus mesopotamicus; Ultrastructure. |
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Categoria do assunto: |
H Saúde e Patologia |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/214921/1/Queiroz-effects-sublethal-2020.pdf
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Marc: |
LEADER 03546naa a2200373 a 4500
001 2124070
005 2020-07-28
008 2020 bl uuuu u00u1 u #d
024 7 $awww.doi.org/10.14202/vetworld.2020.147-159$2DOI
100 1 $aDELCORSO, M. C.
245 $aEffects of sublethal and realistic concentrations of the commercial herbicide atrazine in Pacu (Piaractus mesopotamicus)$blong-term exposure and recovery assays.$h[electronic resource]
260 $c2020
520 $aAbstract: Background and Aim: The commercial formulations of the herbicide atrazine (cATZ) are widely employed in Brazilian agriculture, and, as a consequence, ATZ has been found at levels above that established by law in the river basins in Brazil. Although the toxicity of ATZ in fish is well documented, there are few studies on the recovery capacity after cATZ exposure. This work aimed to evaluate, using several biomarkers, the toxic effects of long-term exposure to the sublethal (3.57 mg/L) and nonlethal realistic (3.00 ?g/L) cATZ concentrations followed by a recovery assay, in fingerlings of a Brazilian teleost, the Piaractus mesopotamicus (pacu). Materials and Methods: Pacu fingerlings were housed in glass tanks and divided into the following experimental groups (two tanks/group): Exposure control = EC, recovery control = RC, the sublethal groups exposed to 3.57 mg/L of cATZ, (sublethal exposure group = SLE and sublethal recovery group = SLR) and the nonlethal groups treated with 3.00 μg/L of cATZ (nonlethal exposure group = NLE and nonlethal recovery group = NLR). The exposure assay was semi-static with a duration of 30 days and the recovery assay (after cATZ withdrawal) lasted 14 days. Several biomarkers were evaluated in fingerlings from all groups: The swimming behavior, the body weight gain, the micronucleus formation and nuclear alterations in erythrocytes, and the hepatic and renal histopathology analyzed by qualitative and semi-quantitative morphological methods (using light and electron microscopy). Results: No significant difference in weight gain was observed among the groups after the exposure and recovery assays. The sublethal exposure induced impaired swimming movements, significant histopathological alterations, including necrosis in the liver and kidney, and a significant increase in the frequency of micronuclei in erythrocytes. The nonlethal exposure induced only subtle histopathological changes in the liver and kidney. After recovery assay, no genotoxic alteration was noted in pacu exposed to sublethal concentration, while the cATZ-induced kidney damage was partially reversed but not the hepatic injury. Conclusion: cATZ exhibits long-term toxic effects on pacu, even at relatively low concentrations, affecting mainly the liver and the kidney, and the effects of sublethal concentration are only partially reversed after cATZ withdrawal.
650 $aAtrazine
650 $aGenotoxicity
650 $aHerbicides
650 $aHistopathology
650 $aPiaractus mesopotamicus
650 $aUltrastructure
650 $aHerbicida
650 $aPacu
650 $aPoluição da Água
650 $aToxidez
653 $aBrazilian ichthyofauna
653 $aKidney lesions
653 $aLiver lesions
653 $aRecovery assay
653 $aToxicidade
700 1 $aPAIVA, P. P. de
700 1 $aGRIGOLETO, M. R. P.
700 1 $aQUEIROZ, S. C. do N. de
700 1 $aCOLLARES-BUZATO, C. B.
700 1 $aARANA, S.
773 $tVeterinary World$gv. 13, n. 1, p. 147-159, 2020.
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Embrapa Meio Ambiente (CNPMA) |
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| 1. |  | LIMA, M. L. F.; SOARES, P. T.; RAMOS, C. A. N.; ARAUJO, F. R.; RAMOS, R. A. N.; SOUZA, I. I. F.; FAUSTINO, M. A. G.; ALVES, L. C. A. Molecular detection of Anaplasma platys in a naturally-infected cat in Brazil. Brazilian Journal of Microbiology, v. 41, n. 2, p. 381-385, Apr./June 2010.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: B - 1 |
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