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 | Acesso ao texto completo restrito à biblioteca da Embrapa Pantanal. Para informações adicionais entre em contato com cpap.biblioteca@embrapa.br. |
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Registro Completo |
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Biblioteca(s): |
Embrapa Pantanal. |
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Data corrente: |
17/07/2014 |
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Data da última atualização: |
19/05/2017 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
BORSATO, D. M.; PRUDENTE, A. S.; DOLL-BOSCARDIN, P. M.; BORSATO, A. V.; LUZ, C. F. P.; MAIA, B. H. L. N. S.; CABRINI, D. A.; OTUKI, M. F.; MIGUEL, M. D.; FARAGO, P. V.; MIGUEL, O. G. |
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Afiliação: |
DÉBORA M. BORSATO, UFPR; ARTHUR S. PRUDENTE, UFPR; PATRÍCIA M. DOLL BOSCARDIN, UEPG; AURELIO VINICIUS BORSATO, CPAP; CYNTHIA F. P. LUZ, INSTITUTO DE BOTÂNICA; BEATRIZ H. L. N. S. MAIA, UFPR; DANIELA A. CABRINI, UFPR; MICHEL F. OTUKI, UEPG; MARILIS D. MIGUEL, UFPR; PAULO V. FARAGO, UEPG; OBDULIO G. MIGUEL, UFPR. |
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Título: |
Topical anti-inflammatory activity of a monofloral honey of Mimosa scabrella provided by Melipona marginata during winter in southern Brazil. |
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Ano de publicação: |
2014 |
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Fonte/Imprenta: |
Journal of Medicinal Food, v. 17, n. 7, p. 817-825, 2014. |
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ISSN: |
1096-620X |
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DOI: |
10.1089/jmf.2013.0024 |
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Idioma: |
Inglês |
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Conteúdo: |
Melipona marginata is an endangered species of stingless bee from Brazil that produces honey with particular physicochemical features and a remarkable exotic flavor. To the best of our knowledge, this is the first report devoted to exploring the medicinal potential of this honey. Thus, the aim of this paper was to investigate the potential anti-inflammatory activity of honey extract from M. marginata on skin inflammation. The honey sample was classified as a monofloral honey of Mimosa scabrella. The presence of 11 phenolic compounds as kaempferol and caffeic acid was detected using the highperformance liquid chromatography-electrospray ionization-tandem mass spectrometry (HPLC-UV-ESI-MS) method. The anti-inflammatory activity was measured using a 12-O-tetradecanoylphorbol-13-acetate-induced ear edema model of inflammation in mice. The topical application of the M. marginata honey extract (1.0 mg/ear) was able to reduce ear edema with an inhibitory effect of 54 ? 5%. This extract decreased the myeloperoxidase activity in 75 ? 3%, which suggests a lower leucocyte infiltration that was confirmed by histological analysis. This extract also provided a reduction of 55 ? 14% in the production of reactive oxygen species. This anti-inflammatory activity could be due to a synergic effect of the phenolic compounds identified in the honey sample. Taken together, these results open up new possibilities for the use of M. marginata honey extract in skin disorders. |
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Palavras-Chave: |
Ear edema; HPLC-UV-ESI-MS analysis; Monofloral honey; Pollen analysis; Stingless bee. |
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Thesagro: |
Mimosa Scabrella. |
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Thesaurus Nal: |
phenolic compounds. |
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Categoria do assunto: |
-- |
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Marc: |
LEADER 02512naa a2200349 a 4500
001 1990912
005 2017-05-19
008 2014 bl uuuu u00u1 u #d
022 $a1096-620X
024 7 $a10.1089/jmf.2013.0024$2DOI
100 1 $aBORSATO, D. M.
245 $aTopical anti-inflammatory activity of a monofloral honey of Mimosa scabrella provided by Melipona marginata during winter in southern Brazil.
260 $c2014
520 $aMelipona marginata is an endangered species of stingless bee from Brazil that produces honey with particular physicochemical features and a remarkable exotic flavor. To the best of our knowledge, this is the first report devoted to exploring the medicinal potential of this honey. Thus, the aim of this paper was to investigate the potential anti-inflammatory activity of honey extract from M. marginata on skin inflammation. The honey sample was classified as a monofloral honey of Mimosa scabrella. The presence of 11 phenolic compounds as kaempferol and caffeic acid was detected using the highperformance liquid chromatography-electrospray ionization-tandem mass spectrometry (HPLC-UV-ESI-MS) method. The anti-inflammatory activity was measured using a 12-O-tetradecanoylphorbol-13-acetate-induced ear edema model of inflammation in mice. The topical application of the M. marginata honey extract (1.0 mg/ear) was able to reduce ear edema with an inhibitory effect of 54 ? 5%. This extract decreased the myeloperoxidase activity in 75 ? 3%, which suggests a lower leucocyte infiltration that was confirmed by histological analysis. This extract also provided a reduction of 55 ? 14% in the production of reactive oxygen species. This anti-inflammatory activity could be due to a synergic effect of the phenolic compounds identified in the honey sample. Taken together, these results open up new possibilities for the use of M. marginata honey extract in skin disorders.
650 $aphenolic compounds
650 $aMimosa Scabrella
653 $aEar edema
653 $aHPLC-UV-ESI-MS analysis
653 $aMonofloral honey
653 $aPollen analysis
653 $aStingless bee
700 1 $aPRUDENTE, A. S.
700 1 $aDOLL-BOSCARDIN, P. M.
700 1 $aBORSATO, A. V.
700 1 $aLUZ, C. F. P.
700 1 $aMAIA, B. H. L. N. S.
700 1 $aCABRINI, D. A.
700 1 $aOTUKI, M. F.
700 1 $aMIGUEL, M. D.
700 1 $aFARAGO, P. V.
700 1 $aMIGUEL, O. G.
773 $tJournal of Medicinal Food$gv. 17, n. 7, p. 817-825, 2014.
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Registro original: |
Embrapa Pantanal (CPAP) |
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Origem |
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Classificação |
Cutter |
Registro |
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Status |
URL |
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| Acesso ao texto completo restrito à biblioteca da Embrapa Tabuleiros Costeiros. Para informações adicionais entre em contato com cpatc.biblioteca@embrapa.br. |
Registro Completo
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Biblioteca(s): |
Embrapa Tabuleiros Costeiros. |
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Data corrente: |
19/01/2009 |
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Data da última atualização: |
12/07/2017 |
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Tipo da produção científica: |
Resumo em Anais de Congresso |
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Autoria: |
ANDRADE, J. A.; MACHADO, A.; BERND, R. B. |
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Afiliação: |
Jamile Aguiar Andrade, (estagiária) Embrapa Tabuleiros Costeiros; Andréa Machado, (estagiária) Embrapa Tabuleiros Costeiros; ; Regina Beatriz Bernd, Embrapa Tabuleiros Costeiros.; REGINA BEATRIZ BERND, Cenargen. |
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Título: |
Germinação in vitro de gliricida sepium. |
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Ano de publicação: |
2008 |
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Fonte/Imprenta: |
In: SEMINÁRIO DO PROGRAMA INSTITUCIONAL DE BOLSAS DE INICIAÇÃO CIENTÍFICA - PIBIC/CNPQ, 5.; SEMINÁRIO DO PROGRAMA DE BOLSAS DE INICIAÇÃO CIENTÍFICA - PROBIC/UNIT, 10., 2008, Aracaju: UNIT, 2008. p. 348. |
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Idioma: |
Português |
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Palavras-Chave: |
Gliridia sepium; Resumo. |
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Thesagro: |
Germinação. |
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Categoria do assunto: |
-- |
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Marc: |
LEADER 00586nam a2200157 a 4500
001 1372877
005 2017-07-12
008 2008 bl uuuu u00u1 u #d
100 1 $aANDRADE, J. A.
245 $aGerminação in vitro de gliricida sepium.
260 $aIn: SEMINÁRIO DO PROGRAMA INSTITUCIONAL DE BOLSAS DE INICIAÇÃO CIENTÍFICA - PIBIC/CNPQ, 5.; SEMINÁRIO DO PROGRAMA DE BOLSAS DE INICIAÇÃO CIENTÍFICA - PROBIC/UNIT, 10., 2008, Aracaju: UNIT, 2008. p. 348.$c2008
650 $aGerminação
653 $aGliridia sepium
653 $aResumo
700 1 $aMACHADO, A.
700 1 $aBERND, R. B.
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