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Registro Completo |
Biblioteca(s): |
Embrapa Gado de Leite. |
Data corrente: |
10/12/2021 |
Data da última atualização: |
10/05/2022 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Autoria: |
ZANETTE, R. de S. S.; FAYER, L.; OLIVEIRA, E. R. de; ALMEIDA, C. G.; OLIVEIRA, C. R. de; OLIVEIRA, L. F. C. de; MARANDUBA, C. M. C.; ALVARENGA, E. C.; BRANDAO, H. de M.; MUNK, M. |
Afiliação: |
RAFAELLA DE S. S. ZANETTE, Universidade Federal de Juiz de Fora; LEONARA FAYER, Universidade Federal de Juiz de Fora; EDUARDA R. DE OLIVEIRA, Universidade Federal de Juiz de Fora; CAMILA G. ALMEIDA; CAUE RIBEIRO DE OLIVEIRA, CNPDIA; LUIZ F. C. DE OLIVEIRA, Universidade Federal de Juiz de Fora; CARLOS M. C. MARANDUBA, Universidade Federal de Juiz de Fora; ERIKA C. ALVARENGA, Universidade Federal de São João del-Rei; HUMBERTO DE MELLO BRANDAO, CNPGL; MICHELE MUNK, Universidade Federal de Juiz de Fora. |
Título: |
Cytocompatibility and osteogenic differentiation of stem cells from human exfoliated deciduous teeth with cotton cellulose nanofibers for tissue engineering and regenerative medicine. |
Ano de publicação: |
2022 |
Fonte/Imprenta: |
Journal of Biomaterials Science, Polymer Edition, v. 33, n. 5, p. 627-650, 2022. |
DOI: |
https://doi.org/10.1080/09205063.2021.2008787 |
Idioma: |
Inglês |
Notas: |
Publicado online em 24 nov. 2021. |
Conteúdo: |
Cellulose nanofibers (CNFs) are natural polymers with physical-chemical properties that make them very attractive for modulating stem cell differentiation, a crucial step in tissue engineering and regenerative medicine. Although cellulose is cytocompatible, when materials are in nanoscale, they become more reactive, needing to evaluate its potential toxic effect to ensure safe application. This study aimed to investigate the cytocompatibility of cotton CNF and its differentiation capacity induction on stem cells from human exfoliated deciduous teeth. First, the cotton CNF was characterized. Then, the cytocompatibility and the osteogenic differentiation induced by cotton CNF were examined. The results revealed that cotton CNFs have about 6?18 nm diameters, and the zeta potential was 10 mV. Despite gene expression alteration, the cotton CNF shows good cytocompatibility. The cotton CNF induced an increase in phosphatase alkaline activity and extracellular matrix mineralization. The results indicate that cotton CNF has good cytocompatibility and can promote cell differentiation without using chemical inducers, showing great potential as a new differentiation inductor for tissue engineering and regenerative medicine applications. |
Palavras-Chave: |
Diferenciação osteogênica; Nanomaterial; Nanotoxicidade; Terapia celular. |
Thesagro: |
Algodão; Célula; Celulose. |
Categoria do assunto: |
F Plantas e Produtos de Origem Vegetal |
Marc: |
LEADER 02382naa a2200337 a 4500 001 2137515 005 2022-05-10 008 2022 bl uuuu u00u1 u #d 024 7 $ahttps://doi.org/10.1080/09205063.2021.2008787$2DOI 100 1 $aZANETTE, R. de S. S. 245 $aCytocompatibility and osteogenic differentiation of stem cells from human exfoliated deciduous teeth with cotton cellulose nanofibers for tissue engineering and regenerative medicine.$h[electronic resource] 260 $c2022 500 $aPublicado online em 24 nov. 2021. 520 $aCellulose nanofibers (CNFs) are natural polymers with physical-chemical properties that make them very attractive for modulating stem cell differentiation, a crucial step in tissue engineering and regenerative medicine. Although cellulose is cytocompatible, when materials are in nanoscale, they become more reactive, needing to evaluate its potential toxic effect to ensure safe application. This study aimed to investigate the cytocompatibility of cotton CNF and its differentiation capacity induction on stem cells from human exfoliated deciduous teeth. First, the cotton CNF was characterized. Then, the cytocompatibility and the osteogenic differentiation induced by cotton CNF were examined. The results revealed that cotton CNFs have about 6?18 nm diameters, and the zeta potential was 10 mV. Despite gene expression alteration, the cotton CNF shows good cytocompatibility. The cotton CNF induced an increase in phosphatase alkaline activity and extracellular matrix mineralization. The results indicate that cotton CNF has good cytocompatibility and can promote cell differentiation without using chemical inducers, showing great potential as a new differentiation inductor for tissue engineering and regenerative medicine applications. 650 $aAlgodão 650 $aCélula 650 $aCelulose 653 $aDiferenciação osteogênica 653 $aNanomaterial 653 $aNanotoxicidade 653 $aTerapia celular 700 1 $aFAYER, L. 700 1 $aOLIVEIRA, E. R. de 700 1 $aALMEIDA, C. G. 700 1 $aOLIVEIRA, C. R. de 700 1 $aOLIVEIRA, L. F. C. de 700 1 $aMARANDUBA, C. M. C. 700 1 $aALVARENGA, E. C. 700 1 $aBRANDAO, H. de M. 700 1 $aMUNK, M. 773 $tJournal of Biomaterials Science, Polymer Edition$gv. 33, n. 5, p. 627-650, 2022.
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Embrapa Gado de Leite (CNPGL) |
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Biblioteca(s): |
Embrapa Florestas. |
Data corrente: |
19/04/2001 |
Data da última atualização: |
29/01/2016 |
Autoria: |
LAGOS, J. B.; AMARAL, F. M. R.; NAKASHIMA, T.; MAZZA, M. C. M.; MEDRADO, M. J. |
Afiliação: |
Mazza, Medrado, pesquisadores da Embrapa Florestas. |
Título: |
Estudo fitoquimico e molecular de seis variedades de erva-mate. |
Ano de publicação: |
2000 |
Fonte/Imprenta: |
In: CONGRESSO SUL-AMERICANO DA ERVA MATE, 2.; REUNIAO TECNICA DA ERVA MATE, 3., 2000, Encantado. Anais. Porto Alegre: Comissao dos Organizadores / Universidade do Rio Grande do Sul / Fundacao Estadual de Pesquisa Agropecuaria, 2000. p.403-405. |
Idioma: |
Português |
Palavras-Chave: |
Erva-mate; Genetic variability; Melhoramento genetivo; Variabilidade genetica. |
Thesagro: |
Ilex Paraguariensis. |
Thesaurus NAL: |
genetic improvement; yerba mate. |
Categoria do assunto: |
-- |
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/138089/1/2000-Congresso-ErvaMate-EstudoFitoquimico.pdf
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Marc: |
LEADER 00876naa a2200241 a 4500 001 1301999 005 2016-01-29 008 2000 bl uuuu u00u1 u #d 100 1 $aLAGOS, J. B. 245 $aEstudo fitoquimico e molecular de seis variedades de erva-mate. 260 $c2000 650 $agenetic improvement 650 $ayerba mate 650 $aIlex Paraguariensis 653 $aErva-mate 653 $aGenetic variability 653 $aMelhoramento genetivo 653 $aVariabilidade genetica 700 1 $aAMARAL, F. M. R. 700 1 $aNAKASHIMA, T. 700 1 $aMAZZA, M. C. M. 700 1 $aMEDRADO, M. J. 773 $tIn: CONGRESSO SUL-AMERICANO DA ERVA MATE, 2.; REUNIAO TECNICA DA ERVA MATE, 3., 2000, Encantado. Anais. Porto Alegre: Comissao dos Organizadores / Universidade do Rio Grande do Sul / Fundacao Estadual de Pesquisa Agropecuaria, 2000. p.403-405.
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