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Registro Completo |
Biblioteca(s): |
Embrapa Caprinos e Ovinos. |
Data corrente: |
06/07/2017 |
Data da última atualização: |
06/07/2017 |
Autoria: |
McCANN, J. P.; ULLMANN, M. B.; TEMPLE, M. R.; REIMERS, T. J.; BERGMAN, E. N. |
Título: |
Insulin and glucose responses to glucose injection in fed and fasted obese and lean sheep. |
Ano de publicação: |
1986 |
Fonte/Imprenta: |
The Journal of Nutrition, v. 116, n. 7, p. 1287-1297, Jul. 1986. |
Idioma: |
Inglês |
Conteúdo: |
Abstract: Effects of short-term fasting on the insulin and glucose responses to injected glucose were determined in obese (n = 6) and lean (n = 6) Dorset ewes that were fed a maintenance level of energy intake. Sheep were assigned by Latin-square design to be fasted for 0 (fed), 12 or 24 h before glucose (350 mg/kg) was injected via jugular cannula at 2000 h with at least 7 d between successive tests. Insulin and glucose were quantified in jugular plasma samples. Pretreatment concentrations of insulin were affected (P less than 0.005) only by body condition with higher mean values in obese (23.5 +/- 3.3 microU/ml) than in lean (9.4 +/- 1.0 microU/ml) sheep. Pretreatment concentrations of glucose (53.6 +/- 1.8 mg/dl) were unaffected by body condition and fasting. The insulin responses to glucose, whether determined as absolute levels or response areas above base-line levels, were greater (P less than 0.005) in obese than in lean sheep regardless of fasting period. Insulin and glucose concentrations after glucose injection in lean sheep were unaffected by fasting. In contrast, the insulin response to glucose was greater (P less than 0.005) in fed obese than 12- or 24-h fasted obese sheep while glucose levels in the fed sheep were similar to those in the fasted obese sheep. Thus, factors associated with feeding enhanced the insulin response to glucose in obese sheep. In addition, obesity in sheep was associated with insulin resistance because basal hyperinsulinemia coexisted with euglycemia and because fractional removal rates of injected glucose were similar in obese and lean sheep despite much greater concentrations of insulin in obese sheep. MenosAbstract: Effects of short-term fasting on the insulin and glucose responses to injected glucose were determined in obese (n = 6) and lean (n = 6) Dorset ewes that were fed a maintenance level of energy intake. Sheep were assigned by Latin-square design to be fasted for 0 (fed), 12 or 24 h before glucose (350 mg/kg) was injected via jugular cannula at 2000 h with at least 7 d between successive tests. Insulin and glucose were quantified in jugular plasma samples. Pretreatment concentrations of insulin were affected (P less than 0.005) only by body condition with higher mean values in obese (23.5 +/- 3.3 microU/ml) than in lean (9.4 +/- 1.0 microU/ml) sheep. Pretreatment concentrations of glucose (53.6 +/- 1.8 mg/dl) were unaffected by body condition and fasting. The insulin responses to glucose, whether determined as absolute levels or response areas above base-line levels, were greater (P less than 0.005) in obese than in lean sheep regardless of fasting period. Insulin and glucose concentrations after glucose injection in lean sheep were unaffected by fasting. In contrast, the insulin response to glucose was greater (P less than 0.005) in fed obese than 12- or 24-h fasted obese sheep while glucose levels in the fed sheep were similar to those in the fasted obese sheep. Thus, factors associated with feeding enhanced the insulin response to glucose in obese sheep. In addition, obesity in sheep was associated with insulin resistance because basal hyperinsulinemia coexisted wi... Mostrar Tudo |
Palavras-Chave: |
Blood sugar. |
Thesaurus Nal: |
Animal feeding; Blood; Fasting; Insulin; Obesity; Pharmacology; Sheep. |
Categoria do assunto: |
L Ciência Animal e Produtos de Origem Animal |
Marc: |
LEADER 02374naa a2200265 a 4500 001 2072046 005 2017-07-06 008 1986 bl uuuu u00u1 u #d 100 1 $aMcCANN, J. P. 245 $aInsulin and glucose responses to glucose injection in fed and fasted obese and lean sheep. 260 $c1986 520 $aAbstract: Effects of short-term fasting on the insulin and glucose responses to injected glucose were determined in obese (n = 6) and lean (n = 6) Dorset ewes that were fed a maintenance level of energy intake. Sheep were assigned by Latin-square design to be fasted for 0 (fed), 12 or 24 h before glucose (350 mg/kg) was injected via jugular cannula at 2000 h with at least 7 d between successive tests. Insulin and glucose were quantified in jugular plasma samples. Pretreatment concentrations of insulin were affected (P less than 0.005) only by body condition with higher mean values in obese (23.5 +/- 3.3 microU/ml) than in lean (9.4 +/- 1.0 microU/ml) sheep. Pretreatment concentrations of glucose (53.6 +/- 1.8 mg/dl) were unaffected by body condition and fasting. The insulin responses to glucose, whether determined as absolute levels or response areas above base-line levels, were greater (P less than 0.005) in obese than in lean sheep regardless of fasting period. Insulin and glucose concentrations after glucose injection in lean sheep were unaffected by fasting. In contrast, the insulin response to glucose was greater (P less than 0.005) in fed obese than 12- or 24-h fasted obese sheep while glucose levels in the fed sheep were similar to those in the fasted obese sheep. Thus, factors associated with feeding enhanced the insulin response to glucose in obese sheep. In addition, obesity in sheep was associated with insulin resistance because basal hyperinsulinemia coexisted with euglycemia and because fractional removal rates of injected glucose were similar in obese and lean sheep despite much greater concentrations of insulin in obese sheep. 650 $aAnimal feeding 650 $aBlood 650 $aFasting 650 $aInsulin 650 $aObesity 650 $aPharmacology 650 $aSheep 653 $aBlood sugar 700 1 $aULLMANN, M. B. 700 1 $aTEMPLE, M. R. 700 1 $aREIMERS, T. J. 700 1 $aBERGMAN, E. N. 773 $tThe Journal of Nutrition$gv. 116, n. 7, p. 1287-1297, Jul. 1986.
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Registro original: |
Embrapa Caprinos e Ovinos (CNPC) |
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Biblioteca(s): |
Embrapa Amazônia Oriental. |
Data corrente: |
13/07/2022 |
Data da última atualização: |
03/08/2022 |
Tipo da produção científica: |
Capítulo em Livro Técnico-Científico |
Autoria: |
FERREIRA, M. C.; LAMEIRA, O. A.; BARBOSA, R. K. da C.; CORDEIRO, I. M. C. C. |
Afiliação: |
MÁRLIA COELHO FERREIRA, MPEG; OSMAR ALVES LAMEIRA, CPATU; RENATA KELLY DA COSTA BARBOSA, UFPA; IRACEMA MARIA CASTRO COIMBRA CORDEIRO, TRAMONTINA. |
Título: |
Piper callosum: Elixir-paregórico. |
Ano de publicação: |
2022 |
Fonte/Imprenta: |
In: CORADIN, L.; CAMILLO, J.; VIEIRA, I. C. G. (ed.). Espécies nativas da flora brasileira de valor econômico atual ou potencial: plantas para o futuro: região Norte. Brasília, DF: MMA, 2022. |
Páginas: |
p. 1078-1081. |
Série: |
(Série Biodiversidade, 53). |
Idioma: |
Português |
Palavras-Chave: |
Elixir-paregórico; Piper callosum. |
Categoria do assunto: |
-- |
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/doc/1144689/1/Plantas-para-o-Futuro-Norte-1079-1082.pdf
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Marc: |
LEADER 00709naa a2200193 a 4500 001 2144689 005 2022-08-03 008 2022 bl uuuu u00u1 u #d 100 1 $aFERREIRA, M. C. 245 $aPiper callosum$bElixir-paregórico.$h[electronic resource] 260 $c2022 300 $ap. 1078-1081. 490 $a(Série Biodiversidade, 53). 653 $aElixir-paregórico 653 $aPiper callosum 700 1 $aLAMEIRA, O. A. 700 1 $aBARBOSA, R. K. da C. 700 1 $aCORDEIRO, I. M. C. C. 773 $tIn: CORADIN, L.; CAMILLO, J.; VIEIRA, I. C. G. (ed.). Espécies nativas da flora brasileira de valor econômico atual ou potencial: plantas para o futuro: região Norte. Brasília, DF: MMA, 2022.
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