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 | Acesso ao texto completo restrito à biblioteca da Embrapa Caprinos e Ovinos. Para informações adicionais entre em contato com cnpc.biblioteca@embrapa.br. |
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Registro Completo |
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Biblioteca(s): |
Embrapa Caprinos e Ovinos. |
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Data corrente: |
16/05/2017 |
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Data da última atualização: |
05/02/2018 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
MATOS, A. F. I. M. de; NOBRE, C. O. R.; MONTEIRO, J. P.; BEVILAQUA, C. M. L.; SMITH, W. D.; TEIXEIRA, M. |
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Afiliação: |
Antônio Francisco Igor Magalhães de Matos, Pós-graduação - Universidade Estadual do Ceará (UECE) - Fortaleza, CE, Brazil; Claudelice Oliveira Rosa Nobre, Pós-graduação - Universidade Estadual Vale do Acaraú (UVA) - Sobral, CE, Brazil; JOMAR PATRICIO MONTEIRO, CNPC; Claudia Maria Leal Bevilaqua, UECE - Fortaleza, CE, Brazil; William David Smith, Moredun Research Institute - Penicuik, Midlothian, Scotland, UK; MARCEL TEIXEIRA, CNPC. |
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Título: |
Attempt to control Haemonchus contortus in dairy goats with Barbervax®, a vaccine derived from the nematode gut membrane glycoproteins. |
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Ano de publicação: |
2017 |
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Fonte/Imprenta: |
Small Ruminant Research, Amsterdam, v. 151, p. 1-4, June, 2017. |
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DOI: |
https://doi.org/10.1016/j.smallrumres.2017.03.016 |
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Idioma: |
Inglês |
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Conteúdo: |
Abstract: The nematode Haemonchus contortus is the most important parasite of small ruminants around the world and the major cause of mortality in tropical regions. Goats are putatively more susceptible than sheep to this parasite and alternatives to anthelmintic utilization are constantly being sought especially after the rise of multiple anthelmintic resistance. Here we present results of a trial designed to evaluate Barbervax®, a vaccine containing gut proteins from Haemonchus contortus, in the control of haemoncosis in dairy goats. In this study female Saanen (n = 20) and Anglo Nubian (n = 20) goats aged six months were assigned by breed, body weight and fecal egg counts into four experimental groups (n = 10) (vaccinated or non-vaccinated). Barbervax® was injected subcutaneously, starting with three priming doses 21 days apart followed by boosts every 6 weeks. All animals grazed on the same bushland area and were subjected to natural and artificial worm infection. Mean efficacy over the trial period was 69.8 ± 2.11% and 57.4 ± 2.76% for the Anglo Nubians and Saanens, respectively. Significant differences in packed cell volume (PCV) and total plasma proteins (TPP) values were also observed but only in the Anglo Nubians. The protection afforded by vaccination was considered useful for management of Haemonchus infection in dairy goats by reducing egg counts. Furthermore, the vaccine does not generate chemical residues and could be very interesting for Haemonchus control during milk production. MenosAbstract: The nematode Haemonchus contortus is the most important parasite of small ruminants around the world and the major cause of mortality in tropical regions. Goats are putatively more susceptible than sheep to this parasite and alternatives to anthelmintic utilization are constantly being sought especially after the rise of multiple anthelmintic resistance. Here we present results of a trial designed to evaluate Barbervax®, a vaccine containing gut proteins from Haemonchus contortus, in the control of haemoncosis in dairy goats. In this study female Saanen (n = 20) and Anglo Nubian (n = 20) goats aged six months were assigned by breed, body weight and fecal egg counts into four experimental groups (n = 10) (vaccinated or non-vaccinated). Barbervax® was injected subcutaneously, starting with three priming doses 21 days apart followed by boosts every 6 weeks. All animals grazed on the same bushland area and were subjected to natural and artificial worm infection. Mean efficacy over the trial period was 69.8 ± 2.11% and 57.4 ± 2.76% for the Anglo Nubians and Saanens, respectively. Significant differences in packed cell volume (PCV) and total plasma proteins (TPP) values were also observed but only in the Anglo Nubians. The protection afforded by vaccination was considered useful for management of Haemonchus infection in dairy goats by reducing egg counts. Furthermore, the vaccine does not generate chemical residues and could be very interesting for Haemonchus control dur... Mostrar Tudo |
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Palavras-Chave: |
H-gal-Gp; H11. |
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Thesagro: |
Caprino; Haemonchus Contortus; Nematóide; Vacina. |
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Thesaurus Nal: |
Goats; Nematoda; Nematode infections; Vaccines. |
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Categoria do assunto: |
H Saúde e Patologia |
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Marc: |
LEADER 02470naa a2200313 a 4500
001 2069655
005 2018-02-05
008 2017 bl uuuu u00u1 u #d
024 7 $ahttps://doi.org/10.1016/j.smallrumres.2017.03.016$2DOI
100 1 $aMATOS, A. F. I. M. de
245 $aAttempt to control Haemonchus contortus in dairy goats with Barbervax®, a vaccine derived from the nematode gut membrane glycoproteins.$h[electronic resource]
260 $c2017
520 $aAbstract: The nematode Haemonchus contortus is the most important parasite of small ruminants around the world and the major cause of mortality in tropical regions. Goats are putatively more susceptible than sheep to this parasite and alternatives to anthelmintic utilization are constantly being sought especially after the rise of multiple anthelmintic resistance. Here we present results of a trial designed to evaluate Barbervax®, a vaccine containing gut proteins from Haemonchus contortus, in the control of haemoncosis in dairy goats. In this study female Saanen (n = 20) and Anglo Nubian (n = 20) goats aged six months were assigned by breed, body weight and fecal egg counts into four experimental groups (n = 10) (vaccinated or non-vaccinated). Barbervax® was injected subcutaneously, starting with three priming doses 21 days apart followed by boosts every 6 weeks. All animals grazed on the same bushland area and were subjected to natural and artificial worm infection. Mean efficacy over the trial period was 69.8 ± 2.11% and 57.4 ± 2.76% for the Anglo Nubians and Saanens, respectively. Significant differences in packed cell volume (PCV) and total plasma proteins (TPP) values were also observed but only in the Anglo Nubians. The protection afforded by vaccination was considered useful for management of Haemonchus infection in dairy goats by reducing egg counts. Furthermore, the vaccine does not generate chemical residues and could be very interesting for Haemonchus control during milk production.
650 $aGoats
650 $aNematoda
650 $aNematode infections
650 $aVaccines
650 $aCaprino
650 $aHaemonchus Contortus
650 $aNematóide
650 $aVacina
653 $aH-gal-Gp
653 $aH11
700 1 $aNOBRE, C. O. R.
700 1 $aMONTEIRO, J. P.
700 1 $aBEVILAQUA, C. M. L.
700 1 $aSMITH, W. D.
700 1 $aTEIXEIRA, M.
773 $tSmall Ruminant Research, Amsterdam$gv. 151, p. 1-4, June, 2017.
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Registro original: |
Embrapa Caprinos e Ovinos (CNPC) |
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Biblioteca |
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Origem |
Tipo/Formato |
Classificação |
Cutter |
Registro |
Volume |
Status |
URL |
Voltar
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Registro Completo
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Biblioteca(s): |
Embrapa Recursos Genéticos e Biotecnologia. |
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Data corrente: |
29/01/2008 |
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Data da última atualização: |
18/07/2008 |
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Tipo da produção científica: |
Resumo em Anais de Congresso |
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Circulação/Nível: |
-- - -- |
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Autoria: |
VIANNA, G. R.; RECH, E. L.; ARAGÃO, F. J. L. |
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Título: |
Desenvolvimento de protocolo para transformação genéticade plantas utilizando fragmentos de DNA. |
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Ano de publicação: |
1999 |
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Fonte/Imprenta: |
In: WORKSHOP DO TALENTO ESTUDANTIL DA EMBRAPA RECURSOS GENÉTICOS E BIOTECNOLOGIA, 4., 1999, Brasília. Anais: resumos dos trabalhos. Brasília, DF: EMBRAPA-CENARGEN, 1999. |
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Páginas: |
p. 47. |
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Idioma: |
Português |
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Thesagro: |
Biologia Molecular. |
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Categoria do assunto: |
-- |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/CENARGEN/28875/1/tales1999.pdf
https://www.cenargen.embrapa.br/publica/talento/tales1999.pdf
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Marc: |
LEADER 00576nam a2200145 a 4500
001 1189020
005 2008-07-18
008 1999 bl uuuu u00u1 u #d
100 1 $aVIANNA, G. R.
245 $aDesenvolvimento de protocolo para transformação genéticade plantas utilizando fragmentos de DNA.
260 $aIn: WORKSHOP DO TALENTO ESTUDANTIL DA EMBRAPA RECURSOS GENÉTICOS E BIOTECNOLOGIA, 4., 1999, Brasília. Anais: resumos dos trabalhos. Brasília, DF: EMBRAPA-CENARGEN$c1999
300 $ap. 47.
650 $aBiologia Molecular
700 1 $aRECH, E. L.
700 1 $aARAGÃO, F. J. L.
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Embrapa Recursos Genéticos e Biotecnologia (CENARGEN) |
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