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Registro Completo |
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Biblioteca(s): |
Embrapa Caprinos e Ovinos. |
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Data corrente: |
24/09/2004 |
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Data da última atualização: |
24/09/2004 |
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Autoria: |
WANG, S.; COCKETT, N. E.; MILLER, J. M.; SHAY, T. L.; MACIULIS, A.; SUTTON, D. L.; FOOTE, W. C; HOLYOAK, G. R.; EVANS, R. C.; BUNCH, T. D.; BEEVER, J. E.; CALL, J. W.; TAYLOR, W. D.; MARSHALL, M. R. |
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Título: |
Polymorphic distribution of the ovine prion protein (PrP) gene in scrapie-infected sheep flocks in which embryo transfer was used to circumvent the transmissions of scrapie. |
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Ano de publicação: |
2002 |
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Fonte/Imprenta: |
Theriogenology, v. 57, n. 7, p. 1865-1875, 2002. |
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Idioma: |
Inglês |
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Conteúdo: |
The genetic sequence of the ovine prion protein (PrP) gene between codons 102 and 175 with emphasis on ovine PrP gene codons 136 and 171 was determined, and the polymorphic distribution of the ovine PrP gene in the scrapie-exposed Suffolk embryo donors and offspring from these donors that were transferred to scrapie-free recipient ewes was investigated in this study. The most common genotype was AA136QQ171 (70% and 63% in the donor and offspring flocks, respectively), which is considered a high risk genotype in US Suffolk sheep. Although embryos were collected from scrapie-positive donors and many embryos had the high risk genotype, no scrapie occurred in the resulting offspring. Based upon the results of this study, we conclude that vertical transmission of scrapie can be circumvente using embryo transfer procedures even when the offspring have the high risk genotype. |
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Palavras-Chave: |
Doença viral; PrP; Sequência nucléica; Suffolk. |
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Thesagro: |
DNA; Genética Animal; Ovino; Sistema Nervoso; Transferência de Embrião. |
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Thesaurus Nal: |
scrapie. |
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Categoria do assunto: |
-- |
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Marc: |
LEADER 01991naa a2200397 a 4500
001 1530733
005 2004-09-24
008 2002 bl uuuu u00u1 u #d
100 1 $aWANG, S.
245 $aPolymorphic distribution of the ovine prion protein (PrP) gene in scrapie-infected sheep flocks in which embryo transfer was used to circumvent the transmissions of scrapie.
260 $c2002
520 $aThe genetic sequence of the ovine prion protein (PrP) gene between codons 102 and 175 with emphasis on ovine PrP gene codons 136 and 171 was determined, and the polymorphic distribution of the ovine PrP gene in the scrapie-exposed Suffolk embryo donors and offspring from these donors that were transferred to scrapie-free recipient ewes was investigated in this study. The most common genotype was AA136QQ171 (70% and 63% in the donor and offspring flocks, respectively), which is considered a high risk genotype in US Suffolk sheep. Although embryos were collected from scrapie-positive donors and many embryos had the high risk genotype, no scrapie occurred in the resulting offspring. Based upon the results of this study, we conclude that vertical transmission of scrapie can be circumvente using embryo transfer procedures even when the offspring have the high risk genotype.
650 $ascrapie
650 $aDNA
650 $aGenética Animal
650 $aOvino
650 $aSistema Nervoso
650 $aTransferência de Embrião
653 $aDoença viral
653 $aPrP
653 $aSequência nucléica
653 $aSuffolk
700 1 $aCOCKETT, N. E.
700 1 $aMILLER, J. M.
700 1 $aSHAY, T. L.
700 1 $aMACIULIS, A.
700 1 $aSUTTON, D. L.
700 1 $aFOOTE, W. C
700 1 $aHOLYOAK, G. R.
700 1 $aEVANS, R. C.
700 1 $aBUNCH, T. D.
700 1 $aBEEVER, J. E.
700 1 $aCALL, J. W.
700 1 $aTAYLOR, W. D.
700 1 $aMARSHALL, M. R.
773 $tTheriogenology$gv. 57, n. 7, p. 1865-1875, 2002.
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Registro original: |
Embrapa Caprinos e Ovinos (CNPC) |
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| 1. |  | RAHMATI, M.; WEIHERMÜLLER, L.; VANDERBORGHT, J.; PACHEPSKY, Y. A.; MAO, L.; SADEGHI, S. H.; MOOSAVI, N.; KHEIRFAM, H.; MONTZKA, C.; VAN LOOY, K.; TOTH, B.; HAZBAVI, Z.; AL YAMANI, W.; ALBALASMEH, A. A.; ALGHZAWI, M. Z.; ANGULO-JARAMILLO, R.; ANTONINO, A. C. D.; ARAMPATZIS, G.; ARMINDO, R. A.; ASADI, H.; BAMUTAZE, Y.; BATLLE-AGUILAR, J.; BÉCHET, B.; BECKER, F.; BLÖSCHL, G.; BOHNE, K.; BRAUD, I.; CASTELLANO, C.; CERDÀ, A.; CHALHOUB, M.; CICHOTA, R.; CÍSLEROVÁ, M.; CLOTHIER, B.; COQUET, Y.; CORNELIS, W.; CORRADINI, C.; COUTINHO, A. P.; OLIVEIRA, M. B. de; MACEDO, J. R. de; DURÃES, M. F.; EMAMI, H.; ESKANDARI, I.; FARAJNIA, A.; FLAMMINI, A.; FODOR, N.; GHARAIBEH, M.; GHAVIMIPANAH, M. H.; GHEZZEHEI, T. A.; GIERTZ, S.; HATZIGIANNAKIS, E. G.; HORN, R.; JIMÉNEZ, J. J.; JACQUES, D.; KEESSTRA, S. D.; KELISHADI, H.; KIANI-HARCHEGANI, M.; KOUSELOU, M.; KUMAR JHA, M.; LASSABATERE, L.; LI, X.; LIEBIG, M. A.; LICHNER, L.; LÓPEZ, M. V.; MACHIWAL, D.; MALLANTS, D.; MALLMANN, M. S.; MARQUES, J. D. de O.; MARSHALL, M. R.; MERTENS, J.; MEUNIER, F.; MOHAMMADI, M. H.; MOHANTY, B. P.; PULIDO-MONCADA, M.; MONTENEGRO, S.; MORBIDELLI, R.; MORET-FERNÁNDEZ, D.; MOOSAVI, A. A.; MOSADDEGHI, M. R.; MOUSAVI, S. B.; MOZAFFARI, H.; NABIOLLAHI, K.; NEYSHABOURI, M. R.; OTTONI, M. V.; OTTONI FILHO, T. B.; PAHLAVAN-RAD, M. R.; PANAGOPOULOS, A.; PETH, S.; PEYNEAU, P.-E.; PICCIAFUOCO, T.; POESEN, J.; PULIDO, M.; REINERT, D. J.; REINSCH, S.; REZAEI, M.; ROBERTS, F. P.; ROBINSON, D.; RODRIGO-COMINO, J.; ROTUNNO FILHO, O. C.; SAITO, T.; SUGANUMA, H.; SALTALIPPI, C.; SÁNDOR, R.; SCHÜTT, B.; SEEGER, M.; SEPEHRNIA, N.; SHARIFI MOGHADDAM, E.; SHUKLA, M.; SHUTARO, S.; SORANDO, R.; STANLEY, A. A.; STRAUSS, P.; SU, Z.; TAGHIZADEH-MEHRJARDI, R.; TAGUAS, E.; TEIXEIRA, W. G.; VAEZI, A. R.; VAFAKHAH, M.; VOGEL, T.; VOGELER, I.; VOTRUBOVA, J.; WERNER, S.; WINARSKI, T.; YILMAZ, D.; YOUNG, M. H.; ZACHARIAS, S.; ZENG, Y.; ZHAO, Y.; ZHAO, H.; VEREECKEN, H. Development and analysis of the Soil Water Infiltration Global database. Earth System Science Data, v. 10, n. 3, p. 1237-1263, 2018.| Biblioteca(s): Embrapa Solos. |
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