Data/hora: 08/06/2024 03:47:52

Biblioteca(s): | Embrapa Meio Ambiente.
Data corrente: | 01/10/2013
Data da última atualização: | 01/10/2013
Autoria: | RODRIGUES, A. G.; PING, L. Y.; MARCATO, P. D.; ALVES, O. L.; SILVA, M. C. P.; RUIZ, R. C.; MELO, I. S. de; TASIC, L.; SOUZA, A. O. de.
Afiliação: | ALEXANDRE G. RODRIGUES, INSTITUTO BUTANTAN; LIU YU PING, INSTITUTO BUTANTAN; PRYSCILA D. MARCATO, IQ-UNICAMP; OSWALDO LUIZ ALVES, IQ-UNICAMP; MARIA C. P. SILVA, ICB-USP; RITA C. RUIZ, INSTITUTO BUTANTAN; ITAMAR SOARES DE MELO, CNPMA; LJUBICA TASIC, IQ-UNICAMP; ANA O. DE SOUZA, INSTITUTO BUTANTAN.
Título: | Biogenic antimicrobial silver nanoparticles produced by fungi.
Ano de publicação: | 2013
Fonte/Imprenta: | Applied Microbiology and Biotechnology, New York, v. 97, p. 775-782, 2013.
Idioma: | Inglês
Conteúdo: | Aspergillus tubingensis and Bionectria ochroleuca showed excellent extracellular ability to synthesize silver nanoparticles (Ag NP), spherical in shape and 35± 10 nm in size. Ag NP were characterized by transmission electron microscopy, X-ray diffraction analysis, and photon correlation spectroscopy for particle size and zeta potential. Proteins present in the fungal filtrate and in Ag NP dispersion were analyzed by electrophoresis (sodium dodecyl sulfate polyacrylamide gel electrophoresis). Ag NP showed pronounced antifungal activity against Candida sp, frequently occurring in hospital infections, with minimal inhibitory concentration in the range of 0.11-1.75 ?g/mL. Regarding antibacterial activity, nanoparticles produced by A. tubingensis were more effective compared to the other fungus, inhibiting 98.0 % of Pseudomonas. aeruginosa growth at 0.28 ?g/mL. A. tubingensis synthesized Ag NP with surprisingly high and positive surface potential, differing greatly from all known fungi. These data open the possibility of obtaining biogenic Ag NP with positive surface potential and new applications.
Palavras-Chave: | Ação antimicrobiana; Antimicrobial activity; Bionectria; Bionectria ochroleuca; Candida sp; Mangrove; Silver nanoparticles.
Thesagro: | Fungo; Mangue.
Thesaurus Nal: | Antifungal agents; Aspergillus tubingensis; Fungi.
Categoria do assunto: | S Ciências Biológicas
Registro original: | Embrapa Meio Ambiente (CNPMA)
Exemplares: | CNPMA - (12796-1) - UPC - AP - DD -  -  -  - DIS