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Registro Completo |
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Biblioteca(s): |
Embrapa Caprinos e Ovinos. |
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Data corrente: |
23/06/2017 |
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Data da última atualização: |
23/06/2017 |
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Autoria: |
MANN, G. E.; CAMPBELL, B. K.; McNEILLY, A. S.; BAIRD, D. T. |
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Título: |
Effects of passively immunizing ewes against inhibin and oestradiol during the follicular phase of the oestrous cycle. |
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Ano de publicação: |
1990 |
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Fonte/Imprenta: |
Journal of Endocrinology, v. 125, n. 3, p. 417-424, Jun. 1990. |
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Idioma: |
Inglês |
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Conteúdo: |
Abstract: Passive immunization was used to investigate the importance of inhibin and oestradiol in the control of FSH production during the follicular phase of the oestrous cycle in the sheep. Four groups of five mature Scottish Blackface ewes were injected with normal sheep plasma (control), antiserum to the 1-26 alpha peptide fragment of porcine inhibin, antiserum to oestradiol-17 beta, or a combination of the two antisera, 24 h following cloprostenol-induced luteal regression. There was no difference in the concentration of LH in jugular venous plasma between the control and inhibin-immunized groups following the injection of normal sheep plasma or inhibin antiserum, with both groups exhibiting normal LH surges. In both the groups immunized against oestradiol, the basal concentration of LH rose by 25-30% (P less than 0.05) during the 96-h period following injection, while the LH surge and consequent formation of a corpus luteum was inhibited. In all three immunized groups there was a significant (P less than 0.001) rise in the concentration of FSH starting 3.8-4.8 h after the injection of antiserum. The duration of the rise was similar in the groups injected with oestradiol antiserum alone (43.6 +/- 12.8 h) or in combination with inhibin antiserum (40.6 +/- 11.7 h), but was significantly (P less than 0.05) shorter in the group immunized against inhibin alone |
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Palavras-Chave: |
Drug effects; FSH; Inhibins; Inhibition; LH. |
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Thesagro: |
Estradiol. |
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Thesaurus Nal: |
Blood; cloprostenol; Ovulation; Pharmacology; Physiology; Progesterone; Sheep. |
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Categoria do assunto: |
L Ciência Animal e Produtos de Origem Animal |
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Marc: |
LEADER 02208naa a2200313 a 4500
001 2071386
005 2017-06-23
008 1990 bl uuuu u00u1 u #d
100 1 $aMANN, G. E.
245 $aEffects of passively immunizing ewes against inhibin and oestradiol during the follicular phase of the oestrous cycle.
260 $c1990
520 $aAbstract: Passive immunization was used to investigate the importance of inhibin and oestradiol in the control of FSH production during the follicular phase of the oestrous cycle in the sheep. Four groups of five mature Scottish Blackface ewes were injected with normal sheep plasma (control), antiserum to the 1-26 alpha peptide fragment of porcine inhibin, antiserum to oestradiol-17 beta, or a combination of the two antisera, 24 h following cloprostenol-induced luteal regression. There was no difference in the concentration of LH in jugular venous plasma between the control and inhibin-immunized groups following the injection of normal sheep plasma or inhibin antiserum, with both groups exhibiting normal LH surges. In both the groups immunized against oestradiol, the basal concentration of LH rose by 25-30% (P less than 0.05) during the 96-h period following injection, while the LH surge and consequent formation of a corpus luteum was inhibited. In all three immunized groups there was a significant (P less than 0.001) rise in the concentration of FSH starting 3.8-4.8 h after the injection of antiserum. The duration of the rise was similar in the groups injected with oestradiol antiserum alone (43.6 +/- 12.8 h) or in combination with inhibin antiserum (40.6 +/- 11.7 h), but was significantly (P less than 0.05) shorter in the group immunized against inhibin alone
650 $aBlood
650 $acloprostenol
650 $aOvulation
650 $aPharmacology
650 $aPhysiology
650 $aProgesterone
650 $aSheep
650 $aEstradiol
653 $aDrug effects
653 $aFSH
653 $aInhibins
653 $aInhibition
653 $aLH
700 1 $aCAMPBELL, B. K.
700 1 $aMcNEILLY, A. S.
700 1 $aBAIRD, D. T.
773 $tJournal of Endocrinology$gv. 125, n. 3, p. 417-424, Jun. 1990.
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Registro original: |
Embrapa Caprinos e Ovinos (CNPC) |
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