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Registro Completo |
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Biblioteca(s): |
Embrapa Caprinos e Ovinos. |
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Data corrente: |
26/03/2013 |
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Data da última atualização: |
12/07/2016 |
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Autoria: |
BARBOSA-FERREIRA, M.; PFISTER, J. A.; GOTARDO, A. T.; MAIORKA, P. C.; GORNIAK, S. L. |
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Título: |
Intoxication by Senna occidentalis seeds in pregnant goats: Prenatal and postnatal evaluation. |
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Ano de publicação: |
2011 |
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Fonte/Imprenta: |
Experimental and Toxicologic Pathology, v. 63, n. 3, p. 263-268, Mar. 2011. |
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DOI: |
10.1016/j.etp.2010.01.004 |
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Idioma: |
Inglês |
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Conteúdo: |
Abstract: Senna occidentalis is a weed toxic to different animal species. Very little is known about the effects of prolonged exposure to low doses of S. occidentalis on developmental toxicology. Thus, the present study proposes an approach to evaluate the perinatal toxicity of S. occidentalis seeds in goats. Twenty-one pregnant goats were fed rations containing 0% (control), 1% (Sol group), 2% (So2 group) and 4% (So4 group) mature S. occidentalis seeds from pregnancy detection on day 27 after mating until parturition; weight gains and serum biochemistry were evaluated. Fetuses were evaluated using ultrasonographic measurements; neonates were evaluated by body morphometry, weight gains, and serum biochemistry. Fetal resorption occurred in 2 So4 dams and one dam died. Only a few minor alterations in serum biochemistry occurred in dams and kids; even so one So4 group dam had tissue lesions as vacuolations in hepatocytes and kidneys; necrosis in skeletal and cardiac muscles and for the first time lesions were observed in sciatic nerve cells. No relevant alterations in body morphometry were observed. This study suggests that 4% S. occidentalis seeds is toxic for pregnant goats, but levels of seeds less than 4% have little impact on fetal and post birth body development. (C) 2010 Elsevier GmbH. All rights reserved. |
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Thesagro: |
Cabra; Caprino; Intoxicação animal; Período de gestação; Planta tóxica; Toxidez. |
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Thesaurus Nal: |
Senna occidentalis. |
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Categoria do assunto: |
-- |
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Marc: |
LEADER 02137naa a2200265 a 4500
001 1954210
005 2016-07-12
008 2011 bl uuuu u00u1 u #d
024 7 $a10.1016/j.etp.2010.01.004$2DOI
100 1 $aBARBOSA-FERREIRA, M.
245 $aIntoxication by Senna occidentalis seeds in pregnant goats$bPrenatal and postnatal evaluation.$h[electronic resource]
260 $c2011
520 $aAbstract: Senna occidentalis is a weed toxic to different animal species. Very little is known about the effects of prolonged exposure to low doses of S. occidentalis on developmental toxicology. Thus, the present study proposes an approach to evaluate the perinatal toxicity of S. occidentalis seeds in goats. Twenty-one pregnant goats were fed rations containing 0% (control), 1% (Sol group), 2% (So2 group) and 4% (So4 group) mature S. occidentalis seeds from pregnancy detection on day 27 after mating until parturition; weight gains and serum biochemistry were evaluated. Fetuses were evaluated using ultrasonographic measurements; neonates were evaluated by body morphometry, weight gains, and serum biochemistry. Fetal resorption occurred in 2 So4 dams and one dam died. Only a few minor alterations in serum biochemistry occurred in dams and kids; even so one So4 group dam had tissue lesions as vacuolations in hepatocytes and kidneys; necrosis in skeletal and cardiac muscles and for the first time lesions were observed in sciatic nerve cells. No relevant alterations in body morphometry were observed. This study suggests that 4% S. occidentalis seeds is toxic for pregnant goats, but levels of seeds less than 4% have little impact on fetal and post birth body development. (C) 2010 Elsevier GmbH. All rights reserved.
650 $aSenna occidentalis
650 $aCabra
650 $aCaprino
650 $aIntoxicação animal
650 $aPeríodo de gestação
650 $aPlanta tóxica
650 $aToxidez
700 1 $aPFISTER, J. A.
700 1 $aGOTARDO, A. T.
700 1 $aMAIORKA, P. C.
700 1 $aGORNIAK, S. L.
773 $tExperimental and Toxicologic Pathology$gv. 63, n. 3, p. 263-268, Mar. 2011.
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Embrapa Caprinos e Ovinos (CNPC) |
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