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| Registros recuperados : 299 | |
| 281. |  | MELO, J. O.; MARTINS, L. G. C.; BARROS, B. de A.; PIMENTA, M. R.; LANA, U. G. de P.; DUARTE, C. E. M.; PASTINA, M. M.; GUIMARÃES, C. T.; SCHAFFERT, R. E.; KOCHIAN, L. V.; FONTES, E. P. B.; MAGALHAES, J. V. de. Repeat variants for the SbMATE transporter protect sorghum roots from aluminum toxicity by transcriptional interplay in cis and trans. Proceedings of the National Academy of Sciences of the United States of America, Washington, v. 116, n. 1, p. 313-318, 2019. Publicado online em 13 dez. 2018.| Biblioteca(s): Embrapa Milho e Sorgo. |
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| 282. | | CANIATO, F. F.; GUIMARAES, C. T.; HAMBLIN, M.; BILLOT, C.; RAMI, J.-F.; HUFNAGEL, B.; KOCHIAN, L. V.; LIU, J.; GARCIA, A. A. F.; HASH, C. T.; RAMU, P.; MITCHELL, S.; KRESIVICH, S.; OLIVEIRA, A. C. de; AVELLAR, G. de; BORÉM, A.; GLASZMANN, J.-C.; SCHAFFERT, R. E.; MAGALHAES, J. V. The relationship between population structure and aluminum tolerance in cultivated sorghum. Plos One, San Francisco, v. 6, n. 6, Jun. 2011.| Biblioteca(s): Embrapa Milho e Sorgo. |
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| 283. | | DIAS, K. O. das G.; GEZAN, S. A.; GUIMARAES, C. T.; MAGALHAES, J. V. de; GUIMARAES, P. E. de O.; CARNEIRO, N. P.; PORTUGAL, A. F.; BASTOS, E. A.; CARDOSO, M. J.; ANONI, C. de O.; SOUZA, J. C. de; GUIMARAES, L. J. M.; PASTINA, M. M. Estimating genotype X environment interaction for and genetic correlations among drought tolerance traits in maize via factor analytic multiplicative mixed models. Crop Science, Madison, v. 58, p. 72-83, Jan. 2018. Publicado online em 30 out. 2017.| Biblioteca(s): Embrapa Milho e Sorgo. |
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| 284. | | MAGALHAES, J. V. de; PASTINA, M. M.; GAZAFFI, R.; MENEZES, C. B. de; ROSA, J. R. B. F.; GUIMARAES, C. T.; TARDIN, F. D.; SCHAFFERT, R. E.; GOMIDE, R. L.; ANDRADE, C. de L. T. de; ALBUQUERQUE, P. E. P. de; BASTOS, E. A.; CARDOSO, M. J. Escaneamento genômico para tolerância à seca em sorgo. Sete Lagoas: Embrapa Milho e Sorgo, 2016. 22 p. (Embrapa Milho e Sorgo. Boletim de Pesquisa e Desenvolvimento, 152).| Biblioteca(s): Embrapa Milho e Sorgo. |
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| 285. | | RIBEIRO, A. P.; VINECKY, F.; DUARTE, K. E.; SANTIAGO, T. R.; CASARI, R. A. das C. N.; HELL, A. F.; DIAS, B. B. A.; MARTINS, P. K.; CENTENO, D. da C.; OLIVEIRA, P. A. de; CANÇADO, G. M. de A.; MAGALHAES, J. V. de; KOBAYASHI, A. K.; SOUZA, W. R. de; MOLINARI, H. B. C. Enhanced aluminum tolerance in sugarcane: evaluation of SbMATE overexpression and genome-wide identification of ALMTs in Saccharum spp. BMC Plant Biology, v. 21, p. 1-15, 2021. Article number: 300.| Biblioteca(s): Embrapa Agricultura Digital; Embrapa Agroenergia; Embrapa Milho e Sorgo. |
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| 286. | | PARENTONI, S. N.; SOUZA JUNIOR, C. L. de; ALVES, V. M. C.; GUIMARAES, C.; COELHO, A. M.; PACHECO, C. A. P.; GUIMARAES, P. E. O.; MEIRELLES, W. F.; GUIMARAES, L. J. M.; SILVA, A. R. da; VASCONCELOS, M. J.; MAGALHAES, J. V. de; OLIVEIRA, A. C.; SCHAFFERT, R. E. Eficiência de aquisição e utilização interna de fósforo em milho tropical: importância relativa e critérios de seleção. In: CONGRESSO NACIONAL DE MILHO E SORGO, 27.; SIMPOSIO BRASILEIRO SOBRE A LAGARTA-DO-CARTUCHO, SPODOPTERA FRUGIPERDA, 3.; WORKSHOP SOBRE MANEJO E ETIOLOGIA DA MANCHA BRANCA DO MILHO, 2008, Londrina. Agroenergia, produção de alimentos e mudanças climáticas: desafios para milho e sorgo: trabalhos e palestras. [Londrina]: IAPAR; [Sete Lagoas]: Embrapa Milho e Sorgo, 2008. 1 CD-ROM.| Biblioteca(s): Embrapa Milho e Sorgo. |
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| 287. | | PARENTONI, S. N.; SOUZA JÚNIOR, C. L. de; ALVES, V. M. C.; GUIMARÃES, C.; COELHO, A. M.; PACHEO, C. A. P.; GUIVARÃES, P. E. O.; MEIRELLES, W. F.; GUIMARÃES, L. J. M.; SILVA, A. R. da; VASCONCELOS, M. J.; MAGALHÃES, J. V.; OLIVEIRA, A. C.; SHAFFERT, R. E. Eficiência de aquisição e utilização interna de fósforo em milho tropical: importância relativa e critérios de seleção. In: CONGRESSO NACIONAL DE MILHO E SORGO, 27.; SIMPÓSIO BRASILEIRO SOBRE A LAGARTA-DO-CARTUCHO, SPODOPTERA FRUGIPERDA, 3.; WORKSHOP SOBRE MANEJO E ETIOLOGIA DA MANCHA BRANCA DO MILHO, 2008, Londrina. Agroenergia, produção de alimentos e mudanças climáticas: desafios para milho e sorgo: trabalhos e palestras. [Londrina]: IAPAR; [Sete Lagoas]: Embrapa Milho e Sorgo, 2008. 6 p.| Biblioteca(s): Embrapa Tabuleiros Costeiros. |
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| 288. | | BARROS, B. de A.; CARNEIRO, A. A.; CARNEIRO, N. P.; MAGALHAES, P. C.; ALVES, M. de C.; PINTO, M. de O.; NODA, R. W.; MAGALHAES, J. V. de; GUIMARÃES, C. T.; MENEZES, C. B. de; TARDIN, F. D.; SCHAFFERT, R. E. Identification of candidate genes associated with drought tolerance in sorghum. In: SIMPÓSIO BRASILEIRO DE GENÉTICA MOLECULAR DE PLANTAS, 4., 2013, Bento Gonçalves. Resumos... Bento Gonçalves: Sociedade Brasileira de Genética, 2013. p. 30.| Biblioteca(s): Embrapa Milho e Sorgo. |
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| 289. | | SILVA, K. J. da; PASTINA, M. M.; GUIMARÃES, C. T.; MAGALHAES, J. V. de; PIMENTEL, L. D.; SCHAFFERT, R. E.; PINTO, M. de O.; SOUZA, V. F. de; BERNARDINO, K. da C.; SILVA, M. J. da; BORÉM, A.; MENEZES, C. B. de. Genetic diversity and heterotic grouping of sorghum lines using SNP markers. Scientia Agricola, v. 78, n. 6, e20200039, 2021.| Biblioteca(s): Embrapa Milho e Sorgo. |
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| 290. | | PARENTONI, S. N.; SOUZA JUNIOR, C. L.; ALVES, V. M. C.; COELHO, A. M.; GUIMARAES, P. E. D. O.; PACHECO, C. A. P.; OLIVEIRA, A. C. D.; GUIMARAES, C. T.; MAGALHAES, J. V. D.; VASCONCELOS, M. J. V. D.; MEIRELLES, W. F.; GUIMARAES, L. J. M.; SILVA, A. R. D.; SCHAFFERT, R. E. Genetics of phosphorus efficiency in tropical maize. In: INTERNATIONAL SYMPOSIUM ON PLANT-SOIL INTERACTIONS AT LOW pH, 7., 2009, Guangzhou. Plant-Soil Interactions at Low pH: nutriomic approach. Proceedings... Guangzhou: South China University of Technology, 2009. p. 134.| Biblioteca(s): Embrapa Tabuleiros Costeiros. |
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| 291. | | DIAS, K. O. das G.; GEZAN, S. A.; GUIMARÃES, C. T.; NAZARIAN, A.; SILVA, L. da C. e; PARENTONI, S. N.; GUIMARAES, P. E. de O.; ANONI, C. de O.; PÁDUA, J. M. V.; PINTO, M. de O.; NODA, R. W.; RIBEIRO, C. A. G.; MAGALHAES, J. V. de; GARCIA, A. A. F.; SOUZA, J. C. de; GUIMARAES, L. J. M.; PASTINA, M. M. Improving accuracies of genomic predictions for drought tolerance in maize by joint modeling of additive and dominance effects in multi-environment trials. Heredity, London, v. 121, n. 1, p. 24-37, 2018.| Biblioteca(s): Embrapa Milho e Sorgo. |
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| 292. | | HUFNAGEL, B.; KOCHIAN, L.; AZEVEDO, G. C.; GUIMARAES, C. T.; SOUSA, S. M.; SCHAFFERT, R. E.; ASSIS, L.; NEGRI, B.; LEISER, W.; WEILTZIEN, E.; RATTUNDE, F.; VIANA, J. H.; GARCIA, A. A. F.; GAZAFFI, R.; WISSUWA, M.; HEUER, S.; MAGALHAES, J. V. Improving phosphorus efficiency in sorghum by the identification and validation of sorghum. In: CONFERENCE INTERNATIONAL PLANT & ANIMAL GENOME, 22., 2014, San Diego, CA. [Abstracts]. San Diego: [s.n], 2014.| Biblioteca(s): Embrapa Milho e Sorgo. |
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| 293. | | SOUZA, V. F. de; PEREIRA, G. da S.; PASTINA, M. M.; PARRELLA, R. A. da C.; SIMEONE, M. L. F.; BARROS, B. de A.; NODA, R. W.; SILVA, L. da C. e; MAGALHAES, J. V. de; SCHAFFERT, R. E.; GARCIA, A. A. F.; DAMASCENO, C. M. B. QTL mapping for bioenergy traits in sweet sorghum recombinant inbred lines. G3: Genes, Genomes, Genetics, v. 11, 112021, 2021.| Biblioteca(s): Embrapa Milho e Sorgo. |
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| 294. | | BERNARDINO, K. C.; PASTINA, M. M.; MENEZES, C. B. de; SOUSA, S. M. de; MACIEL, L. S.; CARVALHO JÚNIOR, G.; GUIMARÃES, C. T.; BARROS, B. de A.; SILVA, L. da C. e; CARNEIRO, P. C. S.; SCHAFFERT, R. E.; KOCHIAN, L. V.; MAGALHAES, J. V. de. The genetic architecture of phosphorus efficiency in sorghum involves pleiotropic QTL for root morphology and grain yield under low phosphorus availability in the soil. BMC Plant Biology, v. 19, n. 87, p. 1-15, 2019.| Biblioteca(s): Embrapa Milho e Sorgo. |
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| 295. | | GUIMARAES, C. T.; SIMOES, C. C.; PASTINA, M. M.; MARON, L. G.; MAGALHAES, J. V.; VASCONCELLOS, R. C. C.; GUIMARAES, L. J. M.; LANA, U. G. de P.; TINOCO, C. F. S.; NODA, R. W.; BELICUAS, S. N. J.; KOCHIAN, L. V.; ALVES, V. M. C.; PARENTONI, S. N. Genetic dissection of Al tolerance QTLs in the maize genome by high density SNP scan. BMC Genomics, v. 15, n. 153, p. 1-14, 2014.| Biblioteca(s): Embrapa Milho e Sorgo. |
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| 296. | | MAGALHAES, J. V. de; LIU, J.; GUIMARAES, C. T.; LANA, U. G. de P.; ALVES, V. M. C.; WANG, Y-H.; SCHAFFERT, R. E.; HOEKENGA, O. A.; PINEROS, M. A.; SHAFF, J. E.; KLEIN, P. E.; CARNEIRO, N. P.; COELHO, C. M.; TRICK, H. N.; KOCHIAN, L. V. A gene in the multidrug and toxic compound extrusion (MATE) family confers aluminum tolerance in sorghum. Nature Genetics, New York, v. 39, n. 9, p. 1156-1161, 2007.| Biblioteca(s): Embrapa Milho e Sorgo. |
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| 297. | | SABADIN, P. K.; MALOSETTI, M.; BOER, M. P.; TARDIN, F. D.; SANTOS, F. G.; GUIMARAES, C. T.; GOMIDE, R. L.; ANDRADE, C. L. T.; ALBUQUERQUE, P. E. P.; CANIATO, F. F.; MOLLINARI, M.; MARGARIDO, G. R. A.; OLIVEIRA, B. F.; SCHAFFERT, R. E.; GARCIA, A. A. F.; EEUWIJK, F. A. van; MAGALHAES, J. V. Studying the genetic basis of drought tolerance in sorghum by managed stress trials and adjustments for phenological and plant height differences. Theoretical and Applied Genetics, Berlin, v. 124, p. 1389-1402, 2012.| Biblioteca(s): Embrapa Milho e Sorgo. |
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| 298. | | GAMA, E. E. G. e; SANTOS, F. G. dos; DURAES, F. O. M.; GOMIDE, R. L.; ALBUQUERQUE, P. E. P. de; BASTOS, E. A.; CARDOSO, M. J.; MORGADO, L. B.; ANDRADE, C. de L. T. de; MAGALHAES, J. V. de; MAGALHAES, C. T.; TARDIN, F. D.; GUIMARAES, L. J. M.; SILVA, A. R. da; MAGALHAES, P. C.; CARNEIRO, N. P.; PARENTONI, S. N.; SCHAFFERT, R. E. Drought tolerance phenotyping in maize and sorghum: preliminary, intermediate and advanced evaluations. In: WORKSHOP SUPPORTING EMERGENCE OR REFERENCE DROUGHT TOLERANCE PHENOTYPING CENTERS - DROUGHT PHENOTYPING NETWORK, 2008, Sete Lagoas. Proceedings... Sete Lagoas: Embrapa Milho e Sorgo, 2008. p. 92-120.| Biblioteca(s): Embrapa Meio-Norte; Embrapa Milho e Sorgo. |
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| 299. | | GAMA, E. E. G. e; SANTOS, F. G. dos; DURAES, F. O. M.; GOMIDE, R. L.; ALBUQUERQUE, P. E. P. de; BASTOS, E. A.; CARDOSO, M. J.; MORGADO, L. B.; ANDRADE, C. de L. T. de; MAGALHAES, J. V. de; MAGALHAES, C. T.; TARDIN, F. D.; GUIMARAES, L. J. M.; SILVA, A. R. da; MAGALHAES, P. C.; CARNEIRO, N. P.; PARENTONI, S. N.; SCHAFFERT, R. E. Drought tolerance phenotyping in maize and sorghum: preliminary, intermediate and advanced evaluations. In: WORKSHOP SUPPORTING EMERGENCE OR REFERENCE DROUGHT TOLERANCE PHENOTYPING CENTERS - DROUGHT PHENOTYPING NETWORK, 2008, Sete Lagoas. Proceedings... Sete Lagoas: Embrapa Milho e Sorgo, 2008. p. 92-120.| Biblioteca(s): Embrapa Semiárido. |
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| Registros recuperados : 299 | |
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Registro Completo
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Biblioteca(s): |
Embrapa Suínos e Aves. |
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Data corrente: |
12/08/2022 |
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Data da última atualização: |
12/08/2022 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
A - 1 |
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Autoria: |
IBELLI, A. M. G.; PEIXOTO, J. de O.; ZANELLA, R.; GOUVEIA, J. J. de S.; CANTAO, M. E.; COUTINHO, L. L.; MARCHESI, J. A. P.; DAL PIZZOL, M. S.; MARCELINO, D. E. P.; LEDUR, M. C. |
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Afiliação: |
ADRIANA MERCIA GUARATINI IBELLI, CNPSA; JANE DE OLIVEIRA PEIXOTO, CNPSA; RICARDO ZANELLA, UPF; JOÃO JOSÉ DE SIMONI GOUVEIA, UNIVASF; MAURICIO EGIDIO CANTAO, CNPSA; LUIZ LEHMANN COUTINHO, Esalq; JORGE AUGUSTO PETROLI MARCHESI, USP; MARIANE SPUDEIT DAL PIZZOL, UDESC/Chapecó; DÉBORA ESTER PETRY MARCELINO, FACC; MONICA CORREA LEDUR, CNPSA. |
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Título: |
Downregulation of growth plate genes involved with the onset of femoral head separation in young broilers. |
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Ano de publicação: |
2022 |
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Fonte/Imprenta: |
Frontiers in Physiology, v. 3, n. 941134, 2022. doi: 10.3389/fphys.2022.941134 |
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DOI: |
https://doi.org/10.3389/fphys.2022.941134 |
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Idioma: |
Inglês |
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Conteúdo: |
Abstract: Femoral head separation (FHS) is characterized by the detachment of growth plate (GP) and articular cartilage, occurring in tibia and femur. However, the molecular mechanisms involved with this condition are not completely understood. Therefore, genes and biological processes (BP) involved with FHS were identified in 21-day-old broilers through RNA sequencing of the femoral GP. 13,487 genes were expressed in the chicken femoral head transcriptome of normal and FHS-affected broilers. From those, 34 were differentially expressed (DE; FDR ≤0.05) between groups, where all of them were downregulated in FHS-affected broilers. The main BP were enriched in receptor signaling pathways, ossification, bone mineralization and formation, skeletal morphogenesis, and vascularization. RNA-Seq datasets comparison of normal and FHS-affected broilers with 21, 35 and 42 days of age has shown three shared DE genes (FBN2, C1QTNF8, and XYLT1) in GP among ages. Twelve genes were exclusively DE at 21 days, where 10 have already been characterized (SHISA3, FNDC1, ANGPTL7, LEPR, ENSGALG00000049529, OXTR, ENSGALG00000045154, COL16A1, RASD2, BOC, GDF10, and THSD7B). Twelve SNPs were associated with FHS (p < 0.0001). Out of those, 5 were novel and 7 were existing variants located in 7 genes (RARS, TFPI2, TTI1, MAP4K3, LINK54, and AREL1). We have shown that genes related to chondrogenesis and bone differentiation were downregulated in the GP of FHS-affected young broilers. Therefore, these findings evince that candidate genes pointed out in our study are probably related to the onset of FHS in broilers. MenosAbstract: Femoral head separation (FHS) is characterized by the detachment of growth plate (GP) and articular cartilage, occurring in tibia and femur. However, the molecular mechanisms involved with this condition are not completely understood. Therefore, genes and biological processes (BP) involved with FHS were identified in 21-day-old broilers through RNA sequencing of the femoral GP. 13,487 genes were expressed in the chicken femoral head transcriptome of normal and FHS-affected broilers. From those, 34 were differentially expressed (DE; FDR ≤0.05) between groups, where all of them were downregulated in FHS-affected broilers. The main BP were enriched in receptor signaling pathways, ossification, bone mineralization and formation, skeletal morphogenesis, and vascularization. RNA-Seq datasets comparison of normal and FHS-affected broilers with 21, 35 and 42 days of age has shown three shared DE genes (FBN2, C1QTNF8, and XYLT1) in GP among ages. Twelve genes were exclusively DE at 21 days, where 10 have already been characterized (SHISA3, FNDC1, ANGPTL7, LEPR, ENSGALG00000049529, OXTR, ENSGALG00000045154, COL16A1, RASD2, BOC, GDF10, and THSD7B). Twelve SNPs were associated with FHS (p < 0.0001). Out of those, 5 were novel and 7 were existing variants located in 7 genes (RARS, TFPI2, TTI1, MAP4K3, LINK54, and AREL1). We have shown that genes related to chondrogenesis and bone differentiation were downregulated in the GP of FHS-affected young broilers. Therefore, these... Mostrar Tudo |
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Palavras-Chave: |
FBN2; Femoral head necrosis; FHS; Necrose da cabeça femoral; RNA-Seq. |
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Thesagro: |
Frango; Galinha; Genética Animal. |
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Thesaurus NAL: |
Chickens; Gene expression. |
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Categoria do assunto: |
-- |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/doc/1145416/1/final9937.pdf
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Marc: |
LEADER 02692naa a2200361 a 4500
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008 2022 bl uuuu u00u1 u #d
024 7 $ahttps://doi.org/10.3389/fphys.2022.941134$2DOI
100 1 $aIBELLI, A. M. G.
245 $aDownregulation of growth plate genes involved with the onset of femoral head separation in young broilers.$h[electronic resource]
260 $c2022
520 $aAbstract: Femoral head separation (FHS) is characterized by the detachment of growth plate (GP) and articular cartilage, occurring in tibia and femur. However, the molecular mechanisms involved with this condition are not completely understood. Therefore, genes and biological processes (BP) involved with FHS were identified in 21-day-old broilers through RNA sequencing of the femoral GP. 13,487 genes were expressed in the chicken femoral head transcriptome of normal and FHS-affected broilers. From those, 34 were differentially expressed (DE; FDR ≤0.05) between groups, where all of them were downregulated in FHS-affected broilers. The main BP were enriched in receptor signaling pathways, ossification, bone mineralization and formation, skeletal morphogenesis, and vascularization. RNA-Seq datasets comparison of normal and FHS-affected broilers with 21, 35 and 42 days of age has shown three shared DE genes (FBN2, C1QTNF8, and XYLT1) in GP among ages. Twelve genes were exclusively DE at 21 days, where 10 have already been characterized (SHISA3, FNDC1, ANGPTL7, LEPR, ENSGALG00000049529, OXTR, ENSGALG00000045154, COL16A1, RASD2, BOC, GDF10, and THSD7B). Twelve SNPs were associated with FHS (p < 0.0001). Out of those, 5 were novel and 7 were existing variants located in 7 genes (RARS, TFPI2, TTI1, MAP4K3, LINK54, and AREL1). We have shown that genes related to chondrogenesis and bone differentiation were downregulated in the GP of FHS-affected young broilers. Therefore, these findings evince that candidate genes pointed out in our study are probably related to the onset of FHS in broilers.
650 $aChickens
650 $aGene expression
650 $aFrango
650 $aGalinha
650 $aGenética Animal
653 $aFBN2
653 $aFemoral head necrosis
653 $aFHS
653 $aNecrose da cabeça femoral
653 $aRNA-Seq
700 1 $aPEIXOTO, J. de O.
700 1 $aZANELLA, R.
700 1 $aGOUVEIA, J. J. de S.
700 1 $aCANTAO, M. E.
700 1 $aCOUTINHO, L. L.
700 1 $aMARCHESI, J. A. P.
700 1 $aDAL PIZZOL, M. S.
700 1 $aMARCELINO, D. E. P.
700 1 $aLEDUR, M. C.
773 $tFrontiers in Physiology$gv. 3, n. 941134, 2022. doi: 10.3389/fphys.2022.941134
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Embrapa Suínos e Aves (CNPSA) |
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