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 | Acesso ao texto completo restrito à biblioteca da Embrapa Pecuária Sudeste. Para informações adicionais entre em contato com cppse.biblioteca@embrapa.br. |
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Registro Completo |
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Biblioteca(s): |
Embrapa Pecuária Sudeste. |
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Data corrente: |
07/07/2021 |
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Data da última atualização: |
28/09/2021 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
ROSA, L. K.; COSTA, F. S.; HAUAGGE, C. M.; MOBILE, R. Z.; LIMA, A. A. S. de; AMARAL, C. D. B. do; MACHADO, R. C.; NOGUEIRA, A. R. de A.; BRANCHER, J. A.; ARAUJO, M. R. DE. |
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Afiliação: |
LETÍCIA KREUTZ ROSA, UFPR; FLORIATAN SANTOS COSTA, UFPR; CECÍLIA MORAES HAUAGGE, UFPR; RAFAEL ZANCAN MOBILE, UFPR; ANTONIO ADILSON SOARES DE LIMA, UFPR; CLARICE DIAS BRITTO DO AMARAL, UFPR; RAQUEL CARDOSO MACHADO, UFSCAR; ANA RITA DE ARAUJO NOGUEIRA, CPPSE; JOÃO ARMANDO BRANCHER, PUC-PR; MELISSA RODRIGUES DE ARAUJO, UFPR. |
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Título: |
Oral health, organic and inorganic saliva composition of men with Schizophrenia: case-control study. |
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Ano de publicação: |
2021 |
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Fonte/Imprenta: |
Journal of Trace Elements in Medicine and Biology, v.66, jul. 2021, 126743. |
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Páginas: |
8 p. |
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ISSN: |
0946-672X |
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DOI: |
https://doi.org/10.1016/j.jtemb.2021.126743 |
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Idioma: |
Inglês |
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Conteúdo: |
Background: Schizophrenia (SCZ) presents complex challenges related to diagnosis and clinical monitoring. The study of conditions associated with SCZ can be facilitated by using potential markers and patterns that provide information to support the diagnosis and oral health. Methods: The salivary composition of patients diagnosed with SCZ (n = 50) was evaluated and compared to the control (n = 50). Saliva samples from male patients were collected and clinical parameters were evaluated. The concentration of total proteins and amylase were determined and salivary macro- and microelements were quantified by ICP OES and ICP-MS. Exploratory data analysis based on artificial intelligence tools was used in the investigation. Results: There was a significant increase in the salivary concentrations of Al, Fe, Li, Mg, Na, and V, higher prevalence of caries (p < 0.001), periodontal disease (p < 0.001), and reduced salivary flow rate (p = 0.019) in SCZ patients. Also, samples were grouped into six clusters. As, Co, Cr, Cu, Mn, Mo, Ni, Se, and Sr were correlated with each other, while Fe, K, Li, Ti, and V showed the highest concentrations in the samples distributed in the clusters with the highest association between SZC patients and controls. Conclusions: The results obtained indicate changes in salivary flow, organic composition, and levels of macro- and microelements in SCZ patients. Salivary concentrations of Fe, Mg, and Na may be related to oral conditions, higher prevalence of caries, and periodontal disease. The exploratory analysis showed different patterns in the salivary composition of SCZ patients impacted by associations between oral health conditions and the use of medications. Future studies are encouraged to confirm the results investigated in this study. MenosBackground: Schizophrenia (SCZ) presents complex challenges related to diagnosis and clinical monitoring. The study of conditions associated with SCZ can be facilitated by using potential markers and patterns that provide information to support the diagnosis and oral health. Methods: The salivary composition of patients diagnosed with SCZ (n = 50) was evaluated and compared to the control (n = 50). Saliva samples from male patients were collected and clinical parameters were evaluated. The concentration of total proteins and amylase were determined and salivary macro- and microelements were quantified by ICP OES and ICP-MS. Exploratory data analysis based on artificial intelligence tools was used in the investigation. Results: There was a significant increase in the salivary concentrations of Al, Fe, Li, Mg, Na, and V, higher prevalence of caries (p < 0.001), periodontal disease (p < 0.001), and reduced salivary flow rate (p = 0.019) in SCZ patients. Also, samples were grouped into six clusters. As, Co, Cr, Cu, Mn, Mo, Ni, Se, and Sr were correlated with each other, while Fe, K, Li, Ti, and V showed the highest concentrations in the samples distributed in the clusters with the highest association between SZC patients and controls. Conclusions: The results obtained indicate changes in salivary flow, organic composition, and levels of macro- and microelements in SCZ patients. Salivary concentrations of Fe, Mg, and Na may be related to oral conditions, higher prevalence of cari... Mostrar Tudo |
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Palavras-Chave: |
Exploratory data analysis; Self-organizing map. |
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Thesagro: |
Saliva. |
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Thesaurus Nal: |
Schizophrenia; Trace elements. |
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Categoria do assunto: |
S Ciências Biológicas |
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Marc: |
LEADER 02779naa a2200325 a 4500
001 2132841
005 2021-09-28
008 2021 bl uuuu u00u1 u #d
022 $a0946-672X
024 7 $ahttps://doi.org/10.1016/j.jtemb.2021.126743$2DOI
100 1 $aROSA, L. K.
245 $aOral health, organic and inorganic saliva composition of men with Schizophrenia$bcase-control study.$h[electronic resource]
260 $c2021
300 $a8 p.
520 $aBackground: Schizophrenia (SCZ) presents complex challenges related to diagnosis and clinical monitoring. The study of conditions associated with SCZ can be facilitated by using potential markers and patterns that provide information to support the diagnosis and oral health. Methods: The salivary composition of patients diagnosed with SCZ (n = 50) was evaluated and compared to the control (n = 50). Saliva samples from male patients were collected and clinical parameters were evaluated. The concentration of total proteins and amylase were determined and salivary macro- and microelements were quantified by ICP OES and ICP-MS. Exploratory data analysis based on artificial intelligence tools was used in the investigation. Results: There was a significant increase in the salivary concentrations of Al, Fe, Li, Mg, Na, and V, higher prevalence of caries (p < 0.001), periodontal disease (p < 0.001), and reduced salivary flow rate (p = 0.019) in SCZ patients. Also, samples were grouped into six clusters. As, Co, Cr, Cu, Mn, Mo, Ni, Se, and Sr were correlated with each other, while Fe, K, Li, Ti, and V showed the highest concentrations in the samples distributed in the clusters with the highest association between SZC patients and controls. Conclusions: The results obtained indicate changes in salivary flow, organic composition, and levels of macro- and microelements in SCZ patients. Salivary concentrations of Fe, Mg, and Na may be related to oral conditions, higher prevalence of caries, and periodontal disease. The exploratory analysis showed different patterns in the salivary composition of SCZ patients impacted by associations between oral health conditions and the use of medications. Future studies are encouraged to confirm the results investigated in this study.
650 $aSchizophrenia
650 $aTrace elements
650 $aSaliva
653 $aExploratory data analysis
653 $aSelf-organizing map
700 1 $aCOSTA, F. S.
700 1 $aHAUAGGE, C. M.
700 1 $aMOBILE, R. Z.
700 1 $aLIMA, A. A. S. de
700 1 $aAMARAL, C. D. B. do
700 1 $aMACHADO, R. C.
700 1 $aNOGUEIRA, A. R. de A.
700 1 $aBRANCHER, J. A.
700 1 $aARAUJO, M. R. DE
773 $tJournal of Trace Elements in Medicine and Biology$gv.66, jul. 2021, 126743.
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Registro original: |
Embrapa Pecuária Sudeste (CPPSE) |
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| Registros recuperados : 43 | |
| 4. |  | MACHADO, R. C.; NOGUEIRA, A. R. de A. Estratégias analíticas para determinação de contaminantes em fertilizantes. In: JORNADA CIENTÍFICA DA EMBRAPA SÃO CARLOS, 10., 2018, São Carlos, SP. Anais... São Carlos, SP: Embrapa Instrumentação; Embrapa Pecuária Sudeste, 2018. p.59. (Embrapa Instrumentação. Documentos, 68). Editores técnicos: Daniel Souza Corrêa, Elaine Cristina Paris, Maria Alice Martins, Paulino Ribeiro Villas Boas, Wilson Tadeu Lopes da Silva.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Pecuária Sudeste. |
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| 5. | | MACHADO, R. C.; ARAMENDIA, M.; NOGUEIRA, A. R. de A.; RESANO, M. Interference-free determination of Ca in ultrapure water, concentrated acids and hydrogen peroxide using isotope dilution, ICP-MS and CH3F as a reaction gas. In: JORNADA DE JÓVENES INVESTIGADORES DEL I3A, 6., Zaragoza, España. Anales... Zaragoza, España: University of Zaragoza, 2017. v. 5.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Pecuária Sudeste. |
|  |
| 8. | | MACHADO, R. C.; ARAMENDIA, M.; NOGUEIRA, A. R. de A.; RESANO, M. Determination of As in complex samples using solid sampling high-resolution continuum source graphite furnace atomic absorption spectroscopy. In: COLLOQUIUM SPECTROSCOPICUM INTERNATIONALE, 40., EURO-MEDITERRANEAN SYMPOSIUM ON LIBS, 9., 2017, Pisa, Italy. Proceedings... Pisa, Italy: IUPAC, 2017. p. 32.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Pecuária Sudeste. |
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| 16. | | GAMA-RODRIGUES, E. F. da; GAMA-RODRIGUES, A. C. da; MACHADO, R. C. R.; MÜLLER, M. W. Carbono, Nitrogênio e atividade da biomassa microbiana em solos sob diferentes sistemas de cutivo de cacau no Sul da Bahia. In: CONGRESSO BRASILEIRO DE SISTEMAS AGROFLORESTAIS, 5., 2004, Curitiba. SAFs: desenvolvimento com proteção ambiental: anais. Colombo: Embrapa Florestas, 2004. p.163-165. (Embrapa Florestas. Documentos, 98).| Biblioteca(s): Embrapa Florestas. |
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| 17. | | BALIGAR, V. C.; FAGERIA, N. K.; PAIVA, A. Q.; SILVEIRA, A.; POMELLA, A. W. V.; MACHADO, R. C. R. Light intensity effects on growth and micronutrient uptake by tropical legume cover crops. Journal of Plant Nutrition, v. 29, n. 11, p. 1959-1974, Nov. 2006.| Tipo: Artigo em Periódico Indexado |
| Biblioteca(s): Embrapa Arroz e Feijão. |
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| Registros recuperados : 43 | |
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| Nenhum registro encontrado para a expressão de busca informada. |
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