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Registro Completo |
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Biblioteca(s): |
Embrapa Unidades Centrais. |
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Data corrente: |
21/11/2017 |
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Data da última atualização: |
29/12/2017 |
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Autoria: |
ALMEIDA, A. C.; ANDRADE, V. A.; FONSECA, F. S. A.; MACÊDO, A. A.; SANTOS, R. L.; COLEN, K. G. F.; MARTINS, E. R.; MARCELO, N. A. |
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Afiliação: |
Anna C. Almeida, Instituto de Ciências Agrárias/Universidade Federal de Minas Gerais - UFMG; Viviane A. Andrade, Instituto Federal do Norte de Minas Gerais - IFNMG; Francine S. A. Fonseca, Instituto de Ciências Agrárias/Universidade Federal de Minas Gerais - UFMG; Auricélio A. Macêdo, Departamento de Clínica e Cirugia/Escola de Veterinária - UFMG; Renato L. Santos, Departamento de Clínica e Cirugia/Escola de Veterinária - UFMG; Keila G. F. Colen, Instituto de Ciências Agrárias/Universidade Federal de Minas Gerais - UFMG; Ernane R. Martins, Instituto de Ciências Agrárias/Universidade Federal de Minas Gerais - UFMG; Natália A. Marcelo, Instituto de Ciências Agrárias/Universidade Federal de Minas Gerais - UFMG. |
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Título: |
Acute and chronic toxicity and antimicrobial activity of the extract of Stryphnodendron adstringens (Mart.) Coville. |
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Ano de publicação: |
2017 |
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Fonte/Imprenta: |
Pesquisa Veterinária Brasileira, Rio de Janeiro, v. 37, n. 8, p. 840-846, ago. 2017. |
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Idioma: |
Inglês |
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Notas: |
Título em português: Toxicidade aguda e crônica e atividade antimicrobiana do extrato de Stryphnodendron adstringens (Mart.) Coville. |
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Conteúdo: |
This study evaluated the antimicrobial activity and acute or chronic toxicity of the extract of Stryphnodendron adstringens. The stem bark dry extract was obtained by static maceration with ethanol. Quantification of tannins was performed by the Folin-Denis method, which indicated a total tannin content of 32.7%. The antimicrobial activity of the dry extract of S. adstringens was evaluated by agar-based disk diffusion assay with Escherichia coli (ATCC 25922) and Staphylococcus aureus (ATCC 25923) in the concentration of 200, 400 and 600?L/mL. The results indicated that 600?L/mL inhibited microbial growth, i.e. had antimicrobial activity against these species. Acute and chronic toxic effects of S. adstringens was evaluated in Wistar rats treated with 200, 400, 600 and 800mg/kg of extract, administrated by gavage. Liver degeneration was observed in the group of rats receiving 800mg/kg in chronic exposure, what may indicate some degree of toxicity at this concentration. However, no systemic toxicity was observed at lower doses. Considering the broad use of S. adstringens as a phytotherapeutic agent for various human and animal diseases and the livertoxicity observed at high concentrations, attention should be paid to the possible adverse effect of using the extract from this plant at high concentration. |
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Palavras-Chave: |
Antimicrobial activity; Atividade antimicrobiana; Hematological parameters; Parâmetro bioquímico; Parâmetro hematológico; Stryphnodendron adstringens; Taninos; Toxicidade hepática. |
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Thesagro: |
Barbatimão; Extrato; Toxidez. |
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Thesaurus Nal: |
Blood chemistry; Extracts; Hepatotoxicity; Tannins; Toxicity. |
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Categoria do assunto: |
-- |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/167161/1/Acute-and-chronic-toxicity-and-antimicrobial.pdf
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Marc: |
LEADER 02662naa a2200409 a 4500
001 2080311
005 2017-12-29
008 2017 bl uuuu u00u1 u #d
100 1 $aALMEIDA, A. C.
245 $aAcute and chronic toxicity and antimicrobial activity of the extract of Stryphnodendron adstringens (Mart.) Coville.$h[electronic resource]
260 $c2017
500 $aTítulo em português: Toxicidade aguda e crônica e atividade antimicrobiana do extrato de Stryphnodendron adstringens (Mart.) Coville.
520 $aThis study evaluated the antimicrobial activity and acute or chronic toxicity of the extract of Stryphnodendron adstringens. The stem bark dry extract was obtained by static maceration with ethanol. Quantification of tannins was performed by the Folin-Denis method, which indicated a total tannin content of 32.7%. The antimicrobial activity of the dry extract of S. adstringens was evaluated by agar-based disk diffusion assay with Escherichia coli (ATCC 25922) and Staphylococcus aureus (ATCC 25923) in the concentration of 200, 400 and 600?L/mL. The results indicated that 600?L/mL inhibited microbial growth, i.e. had antimicrobial activity against these species. Acute and chronic toxic effects of S. adstringens was evaluated in Wistar rats treated with 200, 400, 600 and 800mg/kg of extract, administrated by gavage. Liver degeneration was observed in the group of rats receiving 800mg/kg in chronic exposure, what may indicate some degree of toxicity at this concentration. However, no systemic toxicity was observed at lower doses. Considering the broad use of S. adstringens as a phytotherapeutic agent for various human and animal diseases and the livertoxicity observed at high concentrations, attention should be paid to the possible adverse effect of using the extract from this plant at high concentration.
650 $aBlood chemistry
650 $aExtracts
650 $aHepatotoxicity
650 $aTannins
650 $aToxicity
650 $aBarbatimão
650 $aExtrato
650 $aToxidez
653 $aAntimicrobial activity
653 $aAtividade antimicrobiana
653 $aHematological parameters
653 $aParâmetro bioquímico
653 $aParâmetro hematológico
653 $aStryphnodendron adstringens
653 $aTaninos
653 $aToxicidade hepática
700 1 $aANDRADE, V. A.
700 1 $aFONSECA, F. S. A.
700 1 $aMACÊDO, A. A.
700 1 $aSANTOS, R. L.
700 1 $aCOLEN, K. G. F.
700 1 $aMARTINS, E. R.
700 1 $aMARCELO, N. A.
773 $tPesquisa Veterinária Brasileira, Rio de Janeiro$gv. 37, n. 8, p. 840-846, ago. 2017.
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Registro original: |
Embrapa Unidades Centrais (AI-SEDE) |
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Biblioteca |
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Origem |
Tipo/Formato |
Classificação |
Cutter |
Registro |
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URL |
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Registro Completo
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Biblioteca(s): |
Embrapa Milho e Sorgo. |
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Data corrente: |
22/10/2021 |
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Data da última atualização: |
22/10/2021 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
A - 2 |
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Autoria: |
SOUZA, V. F. de; PEREIRA, G. da S.; PASTINA, M. M.; PARRELLA, R. A. da C.; SIMEONE, M. L. F.; BARROS, B. de A.; NODA, R. W.; SILVA, L. da C. e; MAGALHAES, J. V. de; SCHAFFERT, R. E.; GARCIA, A. A. F.; DAMASCENO, C. M. B. |
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Afiliação: |
VANDER FILLIPE DE SOUZA; GUILHERME DA SILVA PEREIRA, Escola Superior de Agricultura "Luiz de Queiroz"; MARIA MARTA PASTINA, CNPMS; RAFAEL AUGUSTO DA COSTA PARRELLA, CNPMS; MARIA LUCIA FERREIRA SIMEONE, CNPMS; BEATRIZ DE ALMEIDA BARROS, CNPMS; ROBERTO WILLIANS NODA, CNPMS; LUCIANO DA COSTA E SILVA, Universidade Federal de Viçosa; JURANDIR VIEIRA DE MAGALHAES, CNPMS; ROBERT EUGENE SCHAFFERT, CNPMS; ANTONIO AUGUSTO FRANCO GARCIA, Escola Superior de Agricultura "Luiz de Queiroz"; CYNTHIA MARIA BORGES DAMASCENO, CNPMS. |
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Título: |
QTL mapping for bioenergy traits in sweet sorghum recombinant inbred lines. |
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Ano de publicação: |
2021 |
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Fonte/Imprenta: |
G3: Genes, Genomes, Genetics, v. 11, 112021, 2021. |
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DOI: |
https://doi.org/10.1093/g3journal/jkab314 |
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Idioma: |
Inglês |
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Conteúdo: |
During the past decade, sweet sorghum (Sorghum bicolor Moench L.) has shown great potential for bioenergy production, especially biofuels. In this study, 223 recombinant inbred lines (RILs) derived from a cross between two sweet sorghum lines (Brandes Wray) were evaluated in three trials. Single-nucleotide polymorphisms (SNPs) derived from genotyping by sequencing of 272 RILs were used to build a high-density genetic map comprising 3,767 SNPs spanning 1,368.83 cM. Multitrait multiple interval mapping (MT-MIM) was carried out to map quantitative trait loci (QTL) for eight bioenergy traits. A total of 33 QTLs were identified for flowering time, plant height, total soluble solids and sucrose (five QTLs each), fibers (four QTLs), and fresh biomass yield, juice extraction yield, and reducing sugars (three QTLs each). QTL hotspots were found on chromosomes 1, 3, 6, 9, and 10, in addition to other QTLs detected on chromosomes 4 and 8. We observed that 14 out of the 33 mapped QTLs were found in all three trials. Upon further development and validation in other crosses, the results provided by the present study have a great potential to be used in marker-assisted selection in sorghum breeding programs for biofuel production. |
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Thesagro: |
Bioenergia; Linhagem; Sorghum Bicolor; Sorgo Açucareiro. |
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Thesaurus NAL: |
Bioethanol; Quantitative trait loci. |
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Categoria do assunto: |
F Plantas e Produtos de Origem Vegetal |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/227109/1/QTL-mapping.pdf
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Marc: |
LEADER 02227naa a2200337 a 4500
001 2135489
005 2021-10-22
008 2021 bl uuuu u00u1 u #d
024 7 $ahttps://doi.org/10.1093/g3journal/jkab314$2DOI
100 1 $aSOUZA, V. F. de
245 $aQTL mapping for bioenergy traits in sweet sorghum recombinant inbred lines.$h[electronic resource]
260 $c2021
520 $aDuring the past decade, sweet sorghum (Sorghum bicolor Moench L.) has shown great potential for bioenergy production, especially biofuels. In this study, 223 recombinant inbred lines (RILs) derived from a cross between two sweet sorghum lines (Brandes Wray) were evaluated in three trials. Single-nucleotide polymorphisms (SNPs) derived from genotyping by sequencing of 272 RILs were used to build a high-density genetic map comprising 3,767 SNPs spanning 1,368.83 cM. Multitrait multiple interval mapping (MT-MIM) was carried out to map quantitative trait loci (QTL) for eight bioenergy traits. A total of 33 QTLs were identified for flowering time, plant height, total soluble solids and sucrose (five QTLs each), fibers (four QTLs), and fresh biomass yield, juice extraction yield, and reducing sugars (three QTLs each). QTL hotspots were found on chromosomes 1, 3, 6, 9, and 10, in addition to other QTLs detected on chromosomes 4 and 8. We observed that 14 out of the 33 mapped QTLs were found in all three trials. Upon further development and validation in other crosses, the results provided by the present study have a great potential to be used in marker-assisted selection in sorghum breeding programs for biofuel production.
650 $aBioethanol
650 $aQuantitative trait loci
650 $aBioenergia
650 $aLinhagem
650 $aSorghum Bicolor
650 $aSorgo Açucareiro
700 1 $aPEREIRA, G. da S.
700 1 $aPASTINA, M. M.
700 1 $aPARRELLA, R. A. da C.
700 1 $aSIMEONE, M. L. F.
700 1 $aBARROS, B. de A.
700 1 $aNODA, R. W.
700 1 $aSILVA, L. da C. e
700 1 $aMAGALHAES, J. V. de
700 1 $aSCHAFFERT, R. E.
700 1 $aGARCIA, A. A. F.
700 1 $aDAMASCENO, C. M. B.
773 $tG3: Genes, Genomes, Genetics$gv. 11, 112021, 2021.
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Registro original: |
Embrapa Milho e Sorgo (CNPMS) |
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