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Registro Completo |
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Biblioteca(s): |
Embrapa Agricultura Digital; Embrapa Milho e Sorgo. |
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Data corrente: |
23/11/2011 |
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Data da última atualização: |
28/09/2017 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
RUIZ, J. C.; D'AFONSECA, V.; SILVA, A.; ALI, A.; PINTO, A. C.; SANTOS, A. R.; ROCHA, A. A. M. C.; LOPES, D. O.; DORELLA, F. A.; PACHECO, L. G. C.; COSTA, M. P.; TURK, M. Z.; SEYFFERT, N.; MORAES, P. M. R. O.; SOARES, S. C.; ALMEIDA, S. S.; CASTRO, T. L. P.; ABREU, V. A. C.; TROST, E.; BAUMBACH, J.; TAUCH, A.; SCHNEIDER, M. P. C.; McCULLOCH, J.; CERDEIRA, L. T.; RAMOS, R. T. J.; ZERLOTINI, A.; DOMINITINI, A.; RESENDE, D. M.; COSER, E. M.; OLIVEIRA, L. M.; PEDROSA, A. L.; VIEIRA, C. U.; GUIMARAES, C. T.; BARTHOLOMEU, D. C.; OLIVEIRA, D. M.; SANTOS, F. R.; RABELO, E. M.; LOBO, F. P.; FRANCO, G. R.; COSTA, A. F.; CASTRO, I. M.; DIAS, S. R. C.; FERRO, J. A.; ORTEGA, J. M.; PAIVA, L. V.; ALMEIDA, J. F.; GOULART, L. R.; FERRO, M. I. T.; CARNEIRO, N. P.; FALCÃO, P. R. K.; GRYNBERG, P.; TEIXEIRA, S. M. R.; BROMMONSCHENKEL, S.; OLIVEIRA, S. C.; MEYER, R.; MOORE, R. J.; MIYOSHI, A.; OLIVEIRA, G. C.; AZEVEDO, V. |
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Afiliação: |
CLAUDIA TEIXEIRA GUIMARAES, CNPMS; NEWTON PORTILHO CARNEIRO, CNPMS. |
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Título: |
Evidence for reductive genome evolution and lateral acquisition of virulence functions in two Corynebacterium pseudotuberculosis strains. |
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Ano de publicação: |
2011 |
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Fonte/Imprenta: |
Plos One, San Francisco, v. 6, n. 4, p. 1-16, 2011. |
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DOI: |
10.1371/journal.pone.0018551 |
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Idioma: |
Inglês |
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Conteúdo: |
Background: Corynebacterium pseudotuberculosis, a Gram-positive, facultative intracellular pathogen, is the etiologic agent of the disease known as caseous lymphadenitis (CL). CL mainly affects small ruminants, such as goats and sheep; it also causes infections in humans, though rarely. This species is distributed worldwide, but it has the most serious economic impact in Oceania, Africa and South America. Although C. pseudotuberculosis causes major health and productivity problems for livestock, little is known about the molecular basis of its pathogenicity. Methodology and Findings: We characterized two C. pseudotuberculosis genomes (Cp1002, isolated from goats; and CpC231, isolated from sheep). Analysis of the predicted genomes showed high similarity in genomic architecture, gene content and genetic order. When C. pseudotuberculosis was compared with other Corynebacterium species, it became evident that this pathogenic species has lost numerous genes, resulting in one of the smallest genomes in the genus. Other differences that could be part of the adaptation to pathogenicity include a lower GC content, of about 52%, and a reduced gene repertoire. The C. pseudotuberculosis genome also includes seven putative pathogenicity islands, which contain several classical virulence factors, including genes for fimbrial subunits, adhesion factors, iron uptake and secreted toxins. Additionally, all of the virulence factors in the islands have characteristics that indicate horizontal transfer. Conclusions: These particular genome characteristics of C. pseudotuberculosis, as well as its acquired virulence factors in pathogenicity islands, provide evidence of its lifestyle and of the pathogenicity pathways used by this pathogen in the infection process. All genomes cited in this study are available in the NCBI Genbank database (http://www.ncbi.nlm.nih.gov/genbank/) under accession numbers CP001809 and CP001829. MenosBackground: Corynebacterium pseudotuberculosis, a Gram-positive, facultative intracellular pathogen, is the etiologic agent of the disease known as caseous lymphadenitis (CL). CL mainly affects small ruminants, such as goats and sheep; it also causes infections in humans, though rarely. This species is distributed worldwide, but it has the most serious economic impact in Oceania, Africa and South America. Although C. pseudotuberculosis causes major health and productivity problems for livestock, little is known about the molecular basis of its pathogenicity. Methodology and Findings: We characterized two C. pseudotuberculosis genomes (Cp1002, isolated from goats; and CpC231, isolated from sheep). Analysis of the predicted genomes showed high similarity in genomic architecture, gene content and genetic order. When C. pseudotuberculosis was compared with other Corynebacterium species, it became evident that this pathogenic species has lost numerous genes, resulting in one of the smallest genomes in the genus. Other differences that could be part of the adaptation to pathogenicity include a lower GC content, of about 52%, and a reduced gene repertoire. The C. pseudotuberculosis genome also includes seven putative pathogenicity islands, which contain several classical virulence factors, including genes for fimbrial subunits, adhesion factors, iron uptake and secreted toxins. Additionally, all of the virulence factors in the islands have characteristics that indicate horizontal t... Mostrar Tudo |
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Palavras-Chave: |
Análise de genoma; Genoma de C pseudotuberculosis; Ilhas de patogenicidade. |
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Thesagro: |
Corynebacterium Pseudotuberculosis; Genética; Patógeno. |
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Thesaurus Nal: |
Caseous lymphadenitis; Genome; Pathogenicity. |
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Categoria do assunto: |
--
H Saúde e Patologia |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/47474/1/Evidence-reductive.pdf
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/53621/1/journal.pone.0018551.pdf
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Marc: |
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024 7 $a10.1371/journal.pone.0018551$2DOI
100 1 $aRUIZ, J. C.
245 $aEvidence for reductive genome evolution and lateral acquisition of virulence functions in two Corynebacterium pseudotuberculosis strains.$h[electronic resource]
260 $c2011
520 $aBackground: Corynebacterium pseudotuberculosis, a Gram-positive, facultative intracellular pathogen, is the etiologic agent of the disease known as caseous lymphadenitis (CL). CL mainly affects small ruminants, such as goats and sheep; it also causes infections in humans, though rarely. This species is distributed worldwide, but it has the most serious economic impact in Oceania, Africa and South America. Although C. pseudotuberculosis causes major health and productivity problems for livestock, little is known about the molecular basis of its pathogenicity. Methodology and Findings: We characterized two C. pseudotuberculosis genomes (Cp1002, isolated from goats; and CpC231, isolated from sheep). Analysis of the predicted genomes showed high similarity in genomic architecture, gene content and genetic order. When C. pseudotuberculosis was compared with other Corynebacterium species, it became evident that this pathogenic species has lost numerous genes, resulting in one of the smallest genomes in the genus. Other differences that could be part of the adaptation to pathogenicity include a lower GC content, of about 52%, and a reduced gene repertoire. The C. pseudotuberculosis genome also includes seven putative pathogenicity islands, which contain several classical virulence factors, including genes for fimbrial subunits, adhesion factors, iron uptake and secreted toxins. Additionally, all of the virulence factors in the islands have characteristics that indicate horizontal transfer. Conclusions: These particular genome characteristics of C. pseudotuberculosis, as well as its acquired virulence factors in pathogenicity islands, provide evidence of its lifestyle and of the pathogenicity pathways used by this pathogen in the infection process. All genomes cited in this study are available in the NCBI Genbank database (http://www.ncbi.nlm.nih.gov/genbank/) under accession numbers CP001809 and CP001829.
650 $aCaseous lymphadenitis
650 $aGenome
650 $aPathogenicity
650 $aCorynebacterium Pseudotuberculosis
650 $aGenética
650 $aPatógeno
653 $aAnálise de genoma
653 $aGenoma de C pseudotuberculosis
653 $aIlhas de patogenicidade
700 1 $aD'AFONSECA, V.
700 1 $aSILVA, A.
700 1 $aALI, A.
700 1 $aPINTO, A. C.
700 1 $aSANTOS, A. R.
700 1 $aROCHA, A. A. M. C.
700 1 $aLOPES, D. O.
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700 1 $aPACHECO, L. G. C.
700 1 $aCOSTA, M. P.
700 1 $aTURK, M. Z.
700 1 $aSEYFFERT, N.
700 1 $aMORAES, P. M. R. O.
700 1 $aSOARES, S. C.
700 1 $aALMEIDA, S. S.
700 1 $aCASTRO, T. L. P.
700 1 $aABREU, V. A. C.
700 1 $aTROST, E.
700 1 $aBAUMBACH, J.
700 1 $aTAUCH, A.
700 1 $aSCHNEIDER, M. P. C.
700 1 $aMcCULLOCH, J.
700 1 $aCERDEIRA, L. T.
700 1 $aRAMOS, R. T. J.
700 1 $aZERLOTINI, A.
700 1 $aDOMINITINI, A.
700 1 $aRESENDE, D. M.
700 1 $aCOSER, E. M.
700 1 $aOLIVEIRA, L. M.
700 1 $aPEDROSA, A. L.
700 1 $aVIEIRA, C. U.
700 1 $aGUIMARAES, C. T.
700 1 $aBARTHOLOMEU, D. C.
700 1 $aOLIVEIRA, D. M.
700 1 $aSANTOS, F. R.
700 1 $aRABELO, E. M.
700 1 $aLOBO, F. P.
700 1 $aFRANCO, G. R.
700 1 $aCOSTA, A. F.
700 1 $aCASTRO, I. M.
700 1 $aDIAS, S. R. C.
700 1 $aFERRO, J. A.
700 1 $aORTEGA, J. M.
700 1 $aPAIVA, L. V.
700 1 $aALMEIDA, J. F.
700 1 $aGOULART, L. R.
700 1 $aFERRO, M. I. T.
700 1 $aCARNEIRO, N. P.
700 1 $aFALCÃO, P. R. K.
700 1 $aGRYNBERG, P.
700 1 $aTEIXEIRA, S. M. R.
700 1 $aBROMMONSCHENKEL, S.
700 1 $aOLIVEIRA, S. C.
700 1 $aMEYER, R.
700 1 $aMOORE, R. J.
700 1 $aMIYOSHI, A.
700 1 $aOLIVEIRA, G. C.
700 1 $aAZEVEDO, V.
773 $tPlos One, San Francisco$gv. 6, n. 4, p. 1-16, 2011.
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Registro original: |
Embrapa Milho e Sorgo (CNPMS) |
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| Registros recuperados : 72 | |
| 61. |  | STAFUZZA, N. B.; ZERLOTINI NETO, A.; LOBO, F. P.; YAMAGISHI, M. E. B.; BUZANSKAS, M. E.; CHUD, T. C.; CAETANO, A. R.; MUNARI, D. P.; GARRICK, D. J.; MACHADO, M. A.; MARTINS, M. F.; CARVALHO, M. R. S.; COLE, J. B.; SILVA, M. V. G. B. Genetiv variants with potencial loss of function in Gyr, Girolando, and Guzerat cattle breeds by resequencing. Journal of Animal Science, v. 95, n. suppl. 4, p. 81, 2017. Abstract of Breeding and Genetics Symposium, Baltimore, 2017.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Recursos Genéticos e Biotecnologia. |
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| 62. | | PANDOLFI, J. R. C.; SILVA, V. S.; KRAMER, B.; LOBO, F. P.; ZANELLI, C. F.; ARAUJO, F. R.; CALICH, V. L. G.; PEIXOTO, J. de O.; CANTAO, M. E.; MORES, N.; LOYOLA, W.; GRINGS, V. H.; COLDEBELLA, A.; SLUSZZ, T.; BORDIN, L. C.; LAZZAROTTI, M.; LOPES, L. dos S.; IBELLI, A. M. G.; AMARAL, A. L. do; TESSMANN, A. L. Prospection and production of recombinant antigens for the diagnosis of animal tuberculosis. In: SIMPÓSIO EMBRAPA LabEx EUA DE SANIDADE ANIMAL, 2., 2012, Brasília. Anais... Brasília: Embrapa Estudos e Capacitação, 2012. p. 50-51. Projeto/Plano de Ação: 11.11.11.111.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Suínos e Aves. |
|  |
| 63. | | CINTRA, L. C.; ZERLOTINI, A.; LOBO, F. P.; SILVA, F. R. da; GIACHETTO, P. F.; KUSER-FALCÃO, P. R. K.; SILVA, L. O. C. da; EGITO, A. A. do; SIQUEIRA, F.; SILVA, N. M. A. da; PAIVA, S. R.; YAMAGISHI, M. E. B.; CAETANO, A. R. De novo assembly of a Nelore (Bos indicus) bull genome based on short read sequences. In: PLANT & ANIMAL GENOME CONFERENCE, 22., 2014, San Diego, CA. [Abstracts]. San Diego: [s.n.], 2014. Não paginado. P554.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Recursos Genéticos e Biotecnologia. |
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| 64. | | CINTRA, L. C.; ZERLOTINI, A.; LOBO, F. P.; SILVA, F. R. da; GIACHETTO, P. F.; KUSER-FALCÃO, P. R. K.; SILVA, L. O. C. da; EGITO, A. A. do; SIQUEIRA, F.; SILVA, N. M. A. da; PAIVA, S. R.; YAMAGISHI, M. E. B.; CAETANO, A. R. De novo assembly of a Nelore (Bos indicus) bull genome based on short read sequences. In: PLANT & ANIMAL GENOME CONFERENCE, 22., 2014, San Diego, CA. [Abstracts...]. San Diego: [s.n.], 2014. Não paginado. P554.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Agricultura Digital. |
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| 65. | | CINTRA, L. C.; ZERLOTINI NETO, A.; LOBO, F. P.; GIACHETTO, P. F.; FALCAO, P. R. K.; SILVA, L. O. C. da; EGITO, A. A. do; SIQUEIRA, F.; SILVA, N. M. A. da; PAIVA, S. R.; YAMAGISHI, M. E. B.; CAETANO, A. R. Next generation sequencing and de novo assembly of a Nelore (Bos indicus) bull genome. In: ANNUAL MEETING OF THE EUROPEAN FEDERATION OF ANIMAL SCIENCE, 64., 2013, Nantes. Abstracts... Session 25, Poster 34| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Recursos Genéticos e Biotecnologia. |
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| 66. | | CINTRA, L. C.; ZERLOTINI NETO, A.; LOBO, F. P.; GIACHETTO, P. F.; FALCAO, P. R. K.; SILVA, L. O. C. da; EGITO, A. A. do; SIQUEIRA, F.; SILVA, N. M. A. da; PAIVA, S. R.; YAMAGISHI, M. E. B.; CAETANO, A. R. Next generation sequencing and de novo assembly of a Nelore (Bos indicus) bull genome. In: ANNUAL MEETING OF THE EUROPEAN FEDERATION OF ANIMAL SCIENCE, 64., 2013, Nantes. Abstracts... Session 25, Poster 34| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Gado de Corte. |
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| 67. | | CINTRA, L. C.; ZERLOTINI NETO, A.; LOBO, F. P.; SILVA, F. R. da; GIACHETTO, P. F.; FALCAO, P. R. K.; SILVA, L. O. C. da; EGITO, A. A. do; SIQUEIRA, F.; SILVA, N. M. A. da; PAIVA, S. R.; YAMAGISHI, M. E. B.; CAETANO, A. R. Sequencing and de novo genome assembley of a Nelore (Bos indicus) bull. In: INTERNATIONAL PLANT & ANIMAL GENOME, 21., 2013, San Diego. Abstracts... Jersey City: Scherago International, 2013. P0522.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Recursos Genéticos e Biotecnologia. |
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| 68. | | CINTRA, L. C.; ZERLOTINI, A.; LOBO, F. P.; SILVA, F. R. da; GIACHETTO, P. F.; KUSER-FALCÃO, P. R.; SILVA, L. O. C. da; EGITO, A. A. do; SIQUEIRA, F.; SILVA, N. M. A. da; PAIVA, S. R.; YAMAGISHI, M. E. B.; CAETANO, A. R. Sequencing and de novo genome assembly of a nelore (Bos indicus) bull. In: INTERNATIONAL PLANT & ANIMAL GENOME, 21., 2013, San Diego. [Abstracts...]. [S.l.: s.n.], 2013. Não paginado. Pôster 0522.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Agricultura Digital; Embrapa Gado de Corte. |
|  |
| 69. | | STAFUZZA, N. B.; ZERLOTINI NETO, A.; LOBO, F. P.; YAMAGISHI, M. E. B.; CHUD, T. C. S.; CAETANO, A. R.; MUNARI, D. P.; GARRICK, D. J.; MACHADO, M. A.; MARTINS, M. F.; CARVALHO, M. R.; COLE, J. B.; SILVA, M. V. G. B. Single nucleotide variants and InDels identified from whole-genome re-sequencing of Guzerat, Gyr, Girolando and Holstein cattle breeds. Plos One, v. 12, n. 3, p. 1-15, 2017. Artigo e0173954. Na publicação: Adhemar Zerlotini, Marcos Vinicius Gualberto Barbosa da Silva.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
| Biblioteca(s): Embrapa Agricultura Digital; Embrapa Gado de Leite; Embrapa Recursos Genéticos e Biotecnologia. |
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| 70. | | STAFUZZA, N. B.; ZERLOTINI, A.; LOBO, F. P.; YAMAGISHI, M. E. B.; CHUD, T. C. S.; CAETANO, A. R.; MUNARI, D. P.; GARRICK, D. J.; COLE, J. B.; MACHADO, M. A.; MARTINS, M. F.; CARVALHO, M. R.; SILVA, M. V. G. B. Single nucleotide variants and indels identified from whole-genome resequencing of Gyr, Girolando, and Holstein cattle breeds. Journal of Animal Science, v. 95, n. 4, p. 80-81, 2017. Edição dos abstracts do Breeding and Genetics Symposium, Baltimore, 2017.| Tipo: Artigo em Anais de Congresso |
| Biblioteca(s): Embrapa Gado de Leite; Embrapa Recursos Genéticos e Biotecnologia. |
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| 71. | | STAFUZZA, N. B.; ZERLOTINI NETO, A.; LOBO, F. P.; YAMAGISHI, M. E. B.; CHUD, T. C. S.; CAETANO, A. R.; MUNARI, D. P.; GARRICK, D. J.; COLE, J. B.; MACHADO, M. A.; MARTINS, M. F.; CARVALHO, M. R.; SILVA, M. V. G. B. Single nucleotide variants and indels identified from whole-genome resequencing of Gyr, Girolando, and Holstein cattle breeds. Journal of Animal Science, v. 95, p. 80-81, 2017. Suplemento 4, Resumo 164. Edição de Abstracts do ASAS-CSAS Annual Meeting and Trade Show, Baltimore, 2017. Na publicação: A. Zerlotini, M. V. G. B. da Silva.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Agricultura Digital. |
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| 72. | | RUIZ, J. C.; D'AFONSECA, V.; SILVA, A.; ALI, A.; PINTO, A. C.; SANTOS, A. R.; ROCHA, A. A. M. C.; LOPES, D. O.; DORELLA, F. A.; PACHECO, L. G. C.; COSTA, M. P.; TURK, M. Z.; SEYFFERT, N.; MORAES, P. M. R. O.; SOARES, S. C.; ALMEIDA, S. S.; CASTRO, T. L. P.; ABREU, V. A. C.; TROST, E.; BAUMBACH, J.; TAUCH, A.; SCHNEIDER, M. P. C.; McCULLOCH, J.; CERDEIRA, L. T.; RAMOS, R. T. J.; ZERLOTINI, A.; DOMINITINI, A.; RESENDE, D. M.; COSER, E. M.; OLIVEIRA, L. M.; PEDROSA, A. L.; VIEIRA, C. U.; GUIMARAES, C. T.; BARTHOLOMEU, D. C.; OLIVEIRA, D. M.; SANTOS, F. R.; RABELO, E. M.; LOBO, F. P.; FRANCO, G. R.; COSTA, A. F.; CASTRO, I. M.; DIAS, S. R. C.; FERRO, J. A.; ORTEGA, J. M.; PAIVA, L. V.; ALMEIDA, J. F.; GOULART, L. R.; FERRO, M. I. T.; CARNEIRO, N. P.; FALCÃO, P. R. K.; GRYNBERG, P.; TEIXEIRA, S. M. R.; BROMMONSCHENKEL, S.; OLIVEIRA, S. C.; MEYER, R.; MOORE, R. J.; MIYOSHI, A.; OLIVEIRA, G. C.; AZEVEDO, V. Evidence for reductive genome evolution and lateral acquisition of virulence functions in two Corynebacterium pseudotuberculosis strains. Plos One, San Francisco, v. 6, n. 4, p. 1-16, 2011.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
| Biblioteca(s): Embrapa Agricultura Digital; Embrapa Milho e Sorgo. |
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| Registros recuperados : 72 | |
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| Nenhum registro encontrado para a expressão de busca informada. |
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