Data/hora: 08/06/2024 07:30:22

Biblioteca(s): | Embrapa Amazônia Ocidental.
Data corrente: | 27/09/2011
Data da última atualização: | 02/02/2018
Autoria: | LIMA, A. M. de; SALEM, J. I.; SOUZA, J. V. B. de; CORTEZ, A. C. A.; CARVALHO, C. M.; CHAVES, F. C. M.; VEIGA JUNIOR, V. F. da.
Afiliação: | Alita Moura de Lima, INPA; Júlia Ignez Salem, INPA; João Vicente Braga de Souza, INPA; Ana Claudia Alves Cortez, INPA; Clarice Maia Carvalho, CBA; FRANCISCO CELIO MAIA CHAVES, CPAA; Valdir Florêncio da Veiga Junior, UFAM.
Título: | Effects of culture filtrates of endophytic fungi obtained from Piper aduncum L. on the growth of Mycobacterium tuberculosis.
Ano de publicação: | 2011
Fonte/Imprenta: | Electronic Journal of Biotechnology, v. 14, n. 4, p. 1-5, 2011.
ISSN: | 0717-3458
DOI: | 10.2225/vol14-issue4-fulltext-11
Idioma: | Inglês
Conteúdo: | Substances that inhibit the growth of Mycobacterium tuberculosis could potentially be used as antibiotics. These substances could also be added to test culture media to improve the speed of tuberculosis diagnosis. The aim of this work was to investigate the influence of culture filtrates of endophytic fungi isolated from P. aduncum L. on the growth of M. tuberculosis. To achieve this objective, the following methodology was used: a) endophytic fungi were isolated from the leaves and stems of P. aduncum L.; b) the isolated fungi were submitted to submerged bioprocessing; c) culture filtrates from the bioprocess were assayed to evaluate their effect on the growth of M. tuberculosis. We isolated 315 fungal types, which represented 85 morphologies, from different parts of P. aduncum L. The bioassays were performed on 82 culture filtrates and 6 plant extracts and resulted in the detection of 1 culture filtrate that stimulated the growth of M. tuberculosis and 15 that inhibited microbial growth. None of the phytochemical extracts had an effect on the growth of M. tuberculosis. In conclusion, we observed that the endophytic fungi isolated from P. aduncum L. (Piperaceae) produced extracellular metabolites (present in the culture filtrate) that affect the growth of M. tuberculosis. These compounds have the potential to be used as antimicrobials or in the diagnosis of tuberculosis.
Palavras-Chave: | Estimulação de crescimento.
Thesagro: | Tuberculose.
Categoria do assunto: | --
URL: | http://ainfo.cnptia.embrapa.br/digital/bitstream/item/42518/1/Piperaduncum-Alita-Celio.pdf
Registro original: | Embrapa Amazônia Ocidental (CPAA)
Exemplares: | CPAA - (24043-1) - UPC - AP - PP - S8839 -  - S8839 - DIS