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Registro Completo |
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Biblioteca(s): |
Embrapa Pecuária Sudeste. |
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Data corrente: |
17/11/2020 |
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Data da última atualização: |
17/11/2020 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
COLNAGO, L. A.; TREVISOL, I. M.; RECH, D. V.; FORATO, L. A.; MITRE, C. I. N.; LEITE, J. P. G.; GIGLIOTI, R.; OKINO, C. H. |
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Afiliação: |
LUIZ ALBERTO COLNAGO, CNPDIA; IARA MARIA TREVISOL, CNPSA; DAIANE VOSS RECH, CNPSA; LUCIMARA APARECIDA FORATO, CNPDIA; CIRLEI IGREJA DO NASCIMENTO MITRE, USP; JOSÉ PAULO GAGLIARDI LEITE, FIOCRUZ; RODRIGO GIGLIOTI, IZ; CINTIA HIROMI OKINO, CPPSE. |
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Título: |
Simple, low-cost and long-lasting film for virus inactivation using avian coronavirus model as challenge. |
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Ano de publicação: |
2020 |
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Fonte/Imprenta: |
International Journal of Environmental Research and Public Health, v. 17, a. 6456, 2020. |
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Páginas: |
1 - 9 |
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DOI: |
10.3390/ijerph17186456 |
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Idioma: |
Inglês |
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Conteúdo: |
The COVID-19 infection, caused by SARS-CoV-2, is inequitably distributed and more lethal among populations with lower socioeconomic status. Direct contact with contaminated surfaces has been among the virus sources, as it remains infective up to days. Several disinfectants have been shown to inactivate SARS-CoV-2, but they rapidly evaporate, are flammable or toxic and may be scarce or inexistent for vulnerable populations. Therefore, we are proposing simple, easy to prepare, low-cost and ecient antiviral films, made with a widely available dishwashing detergent, which can be spread on hands and inanimate surfaces and is expected to maintain virucidal activity for longer periods than the current sanitizers. Avian coronavirus (ACoV) was used as model of the challenge to test the antivirus ecacy of the proposed films. Polystyrene petri dishes were covered with a thin
layer of detergent formula. After drying, the films were exposed to dierent virus doses for 10 min and virus infectivity was determined using embryonated chicken eggs, and RNA virus quantification in allantoic fluids by RT-qPCR. The films inactivated the ACoV (ranging from 103.7 to 106.7 EID50), which is chemically and morphologically similar to SARS-CoV-2, and may constitute an excellent alternative to minimize the spread of COVID-19. |
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Palavras-Chave: |
Antiviral; Coronavirus; Detergent; Film; Sanitization; Virucide. |
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Categoria do assunto: |
H Saúde e Patologia |
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Marc: |
LEADER 02190naa a2200301 a 4500
001 2126684
005 2020-11-17
008 2020 bl uuuu u00u1 u #d
024 7 $a10.3390/ijerph17186456$2DOI
100 1 $aCOLNAGO, L. A.
245 $aSimple, low-cost and long-lasting film for virus inactivation using avian coronavirus model as challenge.$h[electronic resource]
260 $c2020
300 $a1 - 9
520 $aThe COVID-19 infection, caused by SARS-CoV-2, is inequitably distributed and more lethal among populations with lower socioeconomic status. Direct contact with contaminated surfaces has been among the virus sources, as it remains infective up to days. Several disinfectants have been shown to inactivate SARS-CoV-2, but they rapidly evaporate, are flammable or toxic and may be scarce or inexistent for vulnerable populations. Therefore, we are proposing simple, easy to prepare, low-cost and ecient antiviral films, made with a widely available dishwashing detergent, which can be spread on hands and inanimate surfaces and is expected to maintain virucidal activity for longer periods than the current sanitizers. Avian coronavirus (ACoV) was used as model of the challenge to test the antivirus ecacy of the proposed films. Polystyrene petri dishes were covered with a thin layer of detergent formula. After drying, the films were exposed to dierent virus doses for 10 min and virus infectivity was determined using embryonated chicken eggs, and RNA virus quantification in allantoic fluids by RT-qPCR. The films inactivated the ACoV (ranging from 103.7 to 106.7 EID50), which is chemically and morphologically similar to SARS-CoV-2, and may constitute an excellent alternative to minimize the spread of COVID-19.
653 $aAntiviral
653 $aCoronavirus
653 $aDetergent
653 $aFilm
653 $aSanitization
653 $aVirucide
700 1 $aTREVISOL, I. M.
700 1 $aRECH, D. V.
700 1 $aFORATO, L. A.
700 1 $aMITRE, C. I. N.
700 1 $aLEITE, J. P. G.
700 1 $aGIGLIOTI, R.
700 1 $aOKINO, C. H.
773 $tInternational Journal of Environmental Research and Public Health$gv. 17, a. 6456, 2020.
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Registro original: |
Embrapa Pecuária Sudeste (CPPSE) |
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| 1. |  | BRITTO, F. B.; SABÓIA, E. N.; KOBAYASHI, A. K.; LAVIOLA, B. G.; ROSADO-LAVIOLA, T. B.; BENTZEN, P.; DINIZ, F. M. Molecular markers for the assessment of genetic diversity in Jatropha curcas L. In: CONGRESSO BRASILEIRO DE PESQUISA EM PINHÃO MANSO, 1., 2009, Brasília, DF. Anais... Brasília, DF: Embrapa Agroenergia; São Paulo: ABPPM, 2009. Editores: Bruno Galveas Laviola, Sérgio Delmar dos Anjos e Silva, Júlio César Albrecht. 1 CD-ROM.| Tipo: Artigo em Anais de Congresso / Nota Técnica |
| Biblioteca(s): Embrapa Agroenergia. |
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