Data/hora: 08/06/2024 02:58:31

Biblioteca(s): 	Embrapa Caprinos e Ovinos.	
Data corrente: 	16/06/2017	
Data da última atualização: 	16/06/2017	
Autoria: 	STANSFIELD, S. C.; KNIGHT, P. G.; AL MAULY, N. Z.; BRYANT, M. J.	
Título: 	Involvement of endogenous opioid peptides in the neuroendocrine response of ewe lambs to the introduction of a ram.	
Ano de publicação: 	1987	
Fonte/Imprenta: 	Journal of Endocrinology, v. 115, n. 2, p. 333-340, Nov. 1987.	
DOI: 	10.1677/joe.0.1150333	
Idioma: 	Inglês	
Conteúdo: 	Abstract: Prepubertal ewes can, under certain circumstances, be stimulated to ovulate by the novel introduction of a ram. The endocrine response to the presence of the ram is characterized by a rapid increase in the frequency of episodic release of LH. The purpose of this study was to investigate the effect of the presence of a ram on LH pulse frequency in vivo, gonadotrophin-releasing hormone (GnRH) and beta-endorphin concentrations in the median eminence, and on the influence of the endogenous opioid peptide agonist [D-Ala2,N-Phe4,Met(0)ol5]-enkephalin (FK 33-824) on basal and depolarization-induced release of GnRH from median eminence tissue superfused in vitro. The study was performed at two prepubertal ages in August and September. In September, the introduction of a ram resulted in an increase in pulsatile release of LH, which was associated with an increase in the rate of basal release of GnRH from median eminence tissue superfused in vitro, and the development of a marked ability of FK 33-824 to suppress depolarization-induced release of GnRH. The concentration of beta-endorphin in the median eminence was reduced in animals exposed to the ram at this time. In contrast, the introduction of a ram in August failed to stimulate an increase in LH pulse frequency, basal release of GnRH in vitro was not altered and FK 33-824 was ineffective in reducing depolarization-induced release of GnRH. These results suggest that the premature onset of reproductive activity induced by exposure to the ram may involve the participation of the endogenous opioid peptide system.	
Palavras-Chave: 	Beta-Endorphin; LH; Perfusion; Pulsatile Flow; Releasing hormones.	
Thesaurus Nal: 	Metabolism; Physiology; Pituitary hormones; Reproduction; Sheep.	
Categoria do assunto: 	L Ciência Animal e Produtos de Origem Animal	
Registro original: 	Embrapa Caprinos e Ovinos (CNPC)	
Exemplares: 	CNPC - (33865-1) - ADD - AP - PP -  -  -  - DIS