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| Registros recuperados : 23 | |
| 2. |  | SOUZA, M. de L. M. de; JESUS, M. S. C. de; ANTONIASSI, R. Validação do método de análise de alfa e beta-ácidos em lúpulo utilizando menor quantidade de amostra. In: ENCONTRO BRASILEIRO DE PESQUISADORES E PRODUTORES DE LÚPULO, 2., 2021, on-line. Anais... Even3, 2022. 7 p. Organizado pelo Grupo de Pesquisa: Lúpulo, Aplicações e Manejo (LUPAM) em parceria com o grupo Horgbio, ambos da Faculdade de Ciências Agronômicas (UNESP) - Campus de Botucatu, com o apoio da Associação Brasileira dos Produtores do Lúpulo...| Biblioteca(s): Embrapa Agroindústria de Alimentos. |
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| 3. | | SOUA, R. M. de; JESUS, M. S. C. de; ALVES, B. J. R. Desenvolvimento de um método para preparar amostras de material de planta para a determinação de Ca, Cu, Mg, Mn, Fe e Zn por FAAS. Brazilian Applied Science Review, v. 4, n. 3, p. 1811-1821 mai./jun. 2020.| Biblioteca(s): Embrapa Agrobiologia. |
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| 6. | | SANTIAGO, M. C. P. de A.; ANJOS, M. R. dos; JESUS, M. S. C. de; SOUZA, M. de L. M. de; PACHECO, S.; BIZZO, H. R. Análise e caracterização de taninos condensados por cromatografia líquida. Brazilian Journal of Development, Curitiba, v. 6, n. 8, p. 61446-61462, ago. 2020. Analysis and characterization of condensed tannins by liquid chromatography.| Biblioteca(s): Embrapa Agroindústria de Alimentos. |
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| 7. | | DUARTE, G.; FELBERG, I.; CALADO, V.; DE PAULA, J.; JESUS, M. S. C. de; DELIZA, R.; MIGUEL, M. A. L.; FARAH, A. Fermented Soy-coffee Pudding Dessert Containing Probiotics: Product Formulation and Evaluation of Compositional Changes during Fermentation. Journal of Food and Nutrition Research, v. 11, n. 5, p. 333-344. 2023| Biblioteca(s): Embrapa Agroindústria de Alimentos. |
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| 8. | | PIAN, L. B.; GUERRA, J. G. M.; BERBARA, R. L. L.; JESUS, M. S. C. de; BARBOSA JUNIOR, J.; ARAUJO, E. da S. Characterization, nitrogen availability, and agronomic efficiency of fermented composts in organic vegetable production. Organic Agriculture, v. 13, p. 461-481, 2023.| Biblioteca(s): Embrapa Agrobiologia; Embrapa Agroindústria de Alimentos. |
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| 9. | | BORGUINI, R. G.; SANTIAGO, M. C. P. de A.; PACHECO, S.; JESUS, M. S. C. de; NASCIMENTO, L. da S. de M. do; SOARES, J. F. Caracterização química das polpas amarela e roxa de coquinho azedo (Butia capitata (Mart.) Becc) produzidas pela agricultura familiar Chemical characterization of coquinho azedo (Butia capitata (Mart.) Becc) yellow and purple pulp produced by family farming. In: CONGRESSO BRASILEIRO DE AGROECOLOGIA, 12., 2023, Rio de Janeiro. Cadernos de Agroecologia, v. 19, n. 1, 2024, 20 a 23 de novembro de 2023. ABA.| Biblioteca(s): Embrapa Agroindústria de Alimentos. |
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| 13. | | BRAGA, E. C. O.; BORGUINI, R. G.; SANTIAGO, M. C. P. de A.; COUTO, G. A.; NASCIMENTO, L. da S. de M. do; PACHECO, S.; JESUS, M. S. C. de; GODOY, R. L. de O.; TONON, R. V. Influence of carrier agent concentration on the physicochemical properties and antioxidant capacity of jambo pulp powder. In: INTERNATIONAL CONGRESS ON BIOACTIVE COMPOUNDS, 1.; INTERNATIONAL WORKSHOP ON BIOACTIVE COMPOUNDS, 2., 2018, Campinas, SP. Food design and health nutrition. Campinas: UNICAMP, 2018. Não paginado. Poster. 22nd and 23rd November 2018. ICBC.| Biblioteca(s): Embrapa Agroindústria de Alimentos. |
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| 14. | | BORGUINI, R. G.; PACHECO, S.; HIDALGO CHÁVEZ, D. W.; Couto, G. A.; WILHELM, A. E.; SANTIAGO, M. C. P. de A.; NASCIMENTO, L. da S. de M. do; JESUS, M. S. C. de; GODOY, R. L. de O. Carotenoid extraction using edible vegetable oil: an enriched provitamin A product. Scientia Agricola, v. 78, n. 5, p. e20190332, 2021.| Biblioteca(s): Embrapa Agroindústria de Alimentos. |
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| 15. | | JESUS, M. S. C. DE; MARTINS, V. DE C.; SANTIAGO, M. C. P. de A.; GOUVÊA, A. C. M. S.; BODDEY, R. M.; GUERRA, J. G. M.; ESPINDOLA, J. A. A.; PEREIRA, H. M. G.; GODOY, R. L. de O. Characterization of acylated anthocyanins from storage root of purple-fleshed sweet potato, ipomoea batatas L., from organic farming, by HPLC-PDA and ESI-QTOF-MS. In: IBERO-AMERICAN, 1.; BrMASS CONFERENCE ON MASS SPECTROMETRY, 6., 2016, Rio de Janeiro. Resumos Eletrônicos... São Paulo: Sociedade Brasileira de Espectrometria de Massas, 2016. p. 86-88| Biblioteca(s): Embrapa Agroindústria de Alimentos. |
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| 16. | | PACHECO, S.; BORGUINI, R. G.; CARVALHO, C. W. P. de; SÁ, D. de G. C. F. de; NOGUEIRA, R. I.; SANTIAGO, M. C. P. de A.; JESUS, M. S. C. de; GODOY, R. L. de O. Elaboração de óleo de soja enriquecido com carotenoides provitamínicos A para aplicação em snacks. Rio de Janeiro: Embrapa Agroindústria de Alimentos, 2022. 15 p. (Boletim de Pesquisa e Desenvolvimento. Embrapa Agroindústria de Alimentos, 41).| Biblioteca(s): Embrapa Agroindústria de Alimentos. |
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| 17. | | BORGUINI, R. G.; PACHECO, S.; COUTO, G. A.; BRAGA, E. C. de O.; SANTIAGO, M. C. P. de A.; NASCIMENTO, L. da S. de M. do; JESUS, M. S. C. de; GODOY, R. L. de O. Edible vegetal oils enriched with lycopene In: INTERNATIONAL CONGRESS ON BIOACTIVE COMPOUNDS, 1.; INTERNATIONAL WORKSHOP ON BIOACTIVE COMPOUNDS, 2., 2018, Campinas, SP. Food design and health nutrition. Campinas: UNICAMP, 2018. Não paginado. Poster. 22nd and 23rd November 2018. ICBC.| Biblioteca(s): Embrapa Agroindústria de Alimentos. |
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| 18. | | BRAGA, E. C. DE O.; PACHECO, S.; SANTIAGO, M. C. P. de A.; GODOY, R. L. de O.; JESUS, M. S. C. de; MARTINS, V. DE C.; SOUZA, M. DA C.; PORTE, A.; BORGUINI, R. G. Bioactive compounds of Eugenia punicifolia fruits: a rich source of lycopene. Brazilian Journal of Food Technology, v. 26, e2022130, 2023. Compostos bioativos de frutos de Eugenia punicifolia: uma rica fonte de licopeno.| Biblioteca(s): Embrapa Agroindústria de Alimentos. |
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| 19. | | SANTIAGO, M. C. P. de A.; BORGUINI, R. G.; PEIXOTO, F. M.; GODOY, R. L. de O.; GOUVÊA, A. C. M. S.; NASCIMENTO, L. da S. de M. do; PACHECO, S.; JESUS, M. S. C. de. Nutraceutical based on jamelão peel powder In: INTERNATIONAL CONGRESS ON BIOACTIVE COMPOUNDS, 1.; INTERNATIONAL WORKSHOP ON BIOACTIVE COMPOUNDS, 2., 2018, Campinas, SP. Food design and health nutrition. Campinas: UNICAMP, 2018. Não paginado. Poster. 22nd and 23rd November 2018. ICBC.| Biblioteca(s): Embrapa Agroindústria de Alimentos. |
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| 20. | | GODOY, R. L. de O.; GOUVÊA, A. C. M. S.; SANTIAGO, M. C. P. de A.; BORGUINI, R. G.; NASCIMENTO, L. da S. de M. do; PACHECO, S.; JESUS, M. S. C. de; LEAL, N. M. Use of the ion exchange cartridge in the separation of the anthocyanin fraction from the other flavonoids present in the jamelão peel powder In: INTERNATIONAL CONGRESS ON BIOACTIVE COMPOUNDS, 1.; INTERNATIONAL WORKSHOP ON BIOACTIVE COMPOUNDS, 2., 2018, Campinas, SP. Food design and health nutrition. Campinas: UNICAMP, 2018. Não paginado. Poster. 22nd and 23rd November 2018. ICBC.| Biblioteca(s): Embrapa Agroindústria de Alimentos. |
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| Registros recuperados : 23 | |
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Registro Completo
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Biblioteca(s): |
Embrapa Agricultura Digital; Embrapa Pecuária Sudeste. |
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Data corrente: |
16/08/2021 |
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Data da última atualização: |
17/08/2021 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
A - 1 |
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Autoria: |
BRUSCADIN, J. J.; SOUZA, M. M. de; OLIVEIRA, K. S. de; ROCHA, M. I. P.; AFONSO, J.; CARDOSO, T. F.; ZERLOTINI NETO, A.; COUTINHO, L. L.; NICIURA, S. C. M.; REGITANO, L. C. de A. |
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Afiliação: |
JENNIFER JESSICA BRUSCADIN, UFSCAR; MARCELA MARIA DE SOUZA, IOWA STATE UNIVERSITY; KARINA SANTOS DE OLIVEIRA, UFSCAR; MARINA IBELLI PEREIRA ROCHA, UFSCAR; JULIANA AFONSO, ESALQ/USP; TAINÃ FIGUEIREDO CARDOSO; ADHEMAR ZERLOTINI NETO, CNPTIA; LUIZ LEHMANN COUTINHO, ESALQ/USP; SIMONE CRISTINA MEO NICIURA, CPPSE; LUCIANA CORREIA DE ALMEIDA REGITANO, CPPSE. |
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Título: |
Muscle allele-specific expression QTLs may affect meat quality traits in Bos indicus. |
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Ano de publicação: |
2021 |
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Fonte/Imprenta: |
Scientific Reports, v. 11, p. 1-14, 2021. |
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DOI: |
https://doi.org/10.1038/s41598-021-86782-2 |
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Idioma: |
Inglês |
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Notas: |
Article number: 7321. |
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Conteúdo: |
Abstract. Single nucleotide polymorphisms (SNPs) located in transcript sequences showing allele-specific expression (ASE SNPs) were previously identified in the Longissimus thoracis muscle of a Nelore (Bos indicus) population consisting of 190 steers. Given that the allele-specific expression pattern may result from cis-regulatory SNPs, called allele-specific expression quantitative trait loci (aseQTLs), in this study, we searched for aseQTLs in a window of 1 Mb upstream and downstream from each ASE SNP. After this initial analysis, aiming to investigate variants with a potential regulatory role, we further screened our aseQTL data for sequence similarity with transcription factor binding sites and microRNA (miRNA) binding sites. These aseQTLs were overlapped with methylation data from reduced representation bisulfite sequencing (RRBS) obtained from 12 animals of the same population. We identified 1134 aseQTLs associated with 126 different ASE SNPs. For 215 aseQTLs, one allele potentially affected the affinity of a muscle-expressed transcription factor to its binding site. 162 aseQTLs were predicted to affect 149 miRNA binding sites, from which 114 miRNAs were expressed in muscle. Also, 16 aseQTLs were methylated in our population. Integration of aseQTL with GWAS data revealed enrichment for traits such as meat tenderness, ribeye area, and intramuscular fat . To our knowledge, this is the first report of aseQTLs identification in bovine muscle. Our findings indicate that various cis-regulatory and epigenetic mechanisms can affect multiple variants to modulate the allelic expression. Some of the potential regulatory variants described here were associated with the expression pattern of genes related to interesting phenotypes for livestock. Thus, these variants might be useful for the comprehension of the genetic control of these phenotypes. MenosAbstract. Single nucleotide polymorphisms (SNPs) located in transcript sequences showing allele-specific expression (ASE SNPs) were previously identified in the Longissimus thoracis muscle of a Nelore (Bos indicus) population consisting of 190 steers. Given that the allele-specific expression pattern may result from cis-regulatory SNPs, called allele-specific expression quantitative trait loci (aseQTLs), in this study, we searched for aseQTLs in a window of 1 Mb upstream and downstream from each ASE SNP. After this initial analysis, aiming to investigate variants with a potential regulatory role, we further screened our aseQTL data for sequence similarity with transcription factor binding sites and microRNA (miRNA) binding sites. These aseQTLs were overlapped with methylation data from reduced representation bisulfite sequencing (RRBS) obtained from 12 animals of the same population. We identified 1134 aseQTLs associated with 126 different ASE SNPs. For 215 aseQTLs, one allele potentially affected the affinity of a muscle-expressed transcription factor to its binding site. 162 aseQTLs were predicted to affect 149 miRNA binding sites, from which 114 miRNAs were expressed in muscle. Also, 16 aseQTLs were methylated in our population. Integration of aseQTL with GWAS data revealed enrichment for traits such as meat tenderness, ribeye area, and intramuscular fat . To our knowledge, this is the first report of aseQTLs identification in bovine muscle. Our findings indicate that var... Mostrar Tudo |
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Palavras-Chave: |
Allele-specific expression; Allelic expression; Expressão alélica; Imprint genômico; Loci de característica quantitativa; Polimorfismo de nucleotídeo único. |
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Thesagro: |
Bos Indicus; Gado Nelore. |
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Thesaurus NAL: |
Genomic imprinting; Quantitative trait loci; Single nucleotide polymorphism. |
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Categoria do assunto: |
--
G Melhoramento Genético |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/225232/1/MuscleAlleleSpecific.pdf
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Marc: |
LEADER 03076naa a2200385 a 4500
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008 2021 bl uuuu u00u1 u #d
024 7 $ahttps://doi.org/10.1038/s41598-021-86782-2$2DOI
100 1 $aBRUSCADIN, J. J.
245 $aMuscle allele-specific expression QTLs may affect meat quality traits in Bos indicus.$h[electronic resource]
260 $c2021
500 $aArticle number: 7321.
520 $aAbstract. Single nucleotide polymorphisms (SNPs) located in transcript sequences showing allele-specific expression (ASE SNPs) were previously identified in the Longissimus thoracis muscle of a Nelore (Bos indicus) population consisting of 190 steers. Given that the allele-specific expression pattern may result from cis-regulatory SNPs, called allele-specific expression quantitative trait loci (aseQTLs), in this study, we searched for aseQTLs in a window of 1 Mb upstream and downstream from each ASE SNP. After this initial analysis, aiming to investigate variants with a potential regulatory role, we further screened our aseQTL data for sequence similarity with transcription factor binding sites and microRNA (miRNA) binding sites. These aseQTLs were overlapped with methylation data from reduced representation bisulfite sequencing (RRBS) obtained from 12 animals of the same population. We identified 1134 aseQTLs associated with 126 different ASE SNPs. For 215 aseQTLs, one allele potentially affected the affinity of a muscle-expressed transcription factor to its binding site. 162 aseQTLs were predicted to affect 149 miRNA binding sites, from which 114 miRNAs were expressed in muscle. Also, 16 aseQTLs were methylated in our population. Integration of aseQTL with GWAS data revealed enrichment for traits such as meat tenderness, ribeye area, and intramuscular fat . To our knowledge, this is the first report of aseQTLs identification in bovine muscle. Our findings indicate that various cis-regulatory and epigenetic mechanisms can affect multiple variants to modulate the allelic expression. Some of the potential regulatory variants described here were associated with the expression pattern of genes related to interesting phenotypes for livestock. Thus, these variants might be useful for the comprehension of the genetic control of these phenotypes.
650 $aGenomic imprinting
650 $aQuantitative trait loci
650 $aSingle nucleotide polymorphism
650 $aBos Indicus
650 $aGado Nelore
653 $aAllele-specific expression
653 $aAllelic expression
653 $aExpressão alélica
653 $aImprint genômico
653 $aLoci de característica quantitativa
653 $aPolimorfismo de nucleotídeo único
700 1 $aSOUZA, M. M. de
700 1 $aOLIVEIRA, K. S. de
700 1 $aROCHA, M. I. P.
700 1 $aAFONSO, J.
700 1 $aCARDOSO, T. F.
700 1 $aZERLOTINI NETO, A.
700 1 $aCOUTINHO, L. L.
700 1 $aNICIURA, S. C. M.
700 1 $aREGITANO, L. C. de A.
773 $tScientific Reports$gv. 11, p. 1-14, 2021.
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Embrapa Pecuária Sudeste (CPPSE) |
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