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Registro Completo |
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Biblioteca(s): |
Embrapa Pantanal. |
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Data corrente: |
09/04/1996 |
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Data da última atualização: |
03/04/2017 |
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Autoria: |
URQUHART, G. M.; MURRAY, M.; MURRAY, P. K.; JENNINGS, F. W.; BATE, E. |
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Título: |
Immunosuppression in Trypanosoma brucei infections in rats and mice. |
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Ano de publicação: |
1973 |
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Fonte/Imprenta: |
Transactions Royal Society Tropical Medicine Hygiene, v.67, n.4, p.528-535, 1973. |
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Idioma: |
Inglês |
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Conteúdo: |
In rats which N. brasiliensis infection was superimposed on a previously existing T. brucei infection of 3 weeks duration, the normal process of immune expulsion of adult worms did not occur, the production of circulating protective antibody (IgG) and of reaginic antibody (IgE) was grossly impaired and there was no increase in the numbers of mast cells in the intestinal villi. In contrast to this failure of humoral and immediate-types responses, cell-mediated immunity, as measured by oxazolone sensitization of mice with a T. brucei infection, still occured to a significant extent although not so markedly as in uninfected mice. These results, which provide further evidence that infection with T. brucei may induce a significant degree of immunosuppression of the host, are discussed with particular regard to the aetiology of the phenomenon. |
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Thesaurus Nal: |
Trypanosoma. |
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Categoria do assunto: |
-- |
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Marc: |
LEADER 01366naa a2200181 a 4500
001 1788088
005 2017-04-03
008 1973 bl --- 0-- u #d
100 1 $aURQUHART, G. M.
245 $aImmunosuppression in Trypanosoma brucei infections in rats and mice.
260 $c1973
520 $aIn rats which N. brasiliensis infection was superimposed on a previously existing T. brucei infection of 3 weeks duration, the normal process of immune expulsion of adult worms did not occur, the production of circulating protective antibody (IgG) and of reaginic antibody (IgE) was grossly impaired and there was no increase in the numbers of mast cells in the intestinal villi. In contrast to this failure of humoral and immediate-types responses, cell-mediated immunity, as measured by oxazolone sensitization of mice with a T. brucei infection, still occured to a significant extent although not so markedly as in uninfected mice. These results, which provide further evidence that infection with T. brucei may induce a significant degree of immunosuppression of the host, are discussed with particular regard to the aetiology of the phenomenon.
650 $aTrypanosoma
700 1 $aMURRAY, M.
700 1 $aMURRAY, P. K.
700 1 $aJENNINGS, F. W.
700 1 $aBATE, E.
773 $tTransactions Royal Society Tropical Medicine Hygiene$gv.67, n.4, p.528-535, 1973.
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Registro original: |
Embrapa Pantanal (CPAP) |
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