Data/hora: 11/06/2024 09:24:51

Biblioteca(s): | Embrapa Pantanal.
Data corrente: | 22/03/1996
Data da última atualização: | 03/04/2017
Autoria: | SCOTT, J. M.; PEGRAM, R. G.; HOLMES, P. H.; PAY, T. W. F.; KNIGHT, P. A.; JENNINGS, F. W.; URQUHART, G. M.
Título: | Immunosuppression in bovine trypanosomiasis: field studies using foot-and-mouth disease vaccine and clostridial vaccine.
Ano de publicação: | 1977
Fonte/Imprenta: | Tropical Animal Health Production, v.9, p.159-165, 1977.
Idioma: | Inglês
Conteúdo: | The immunosuppresive effect of naturally acquired trypanosomiais was investigated in four groups of zebu cattle maintained in an area of high tsetse fly challenge in Western Ethiopia. Two of the groups remained without chemoprophylaxis against trypanosomiasis and became parasitaemic. The animals of one of these two groups received a polyvalent foot-and-mouth disease vaccine and the cattle of the other group received foot-and-mouth disease vaccine together with a polyvalent clostridial vaccine. The cattle of the remaining two groups, regarded as controls, received fortnightly treatment with Berenil and remained free of trypanopsomiasis; of these one group received foot-and-mounth disease vaccine alone and the other both foot-and-mouth disease vaccine and the clostridial vaccine. Additionally two groups of cattle, one experimentally infected with trypanosomiasis and the other uninfected were also studied in a tsetse-free area. Each group received boith foot-and-mouth disease and clostridial vaccines. In all animals two doses of each vaccine were administered 21 days apart and the resulting antibody titres measured 10 days after the second vaccination. It was found that was a considerable depression in the titres to both vacinnes in the trypanosome infected cattle relative to the controls, the differences being most marked in animals receiving both vaccines. However almost all titres were above those considered necessary to give more than 95 per cent protection to food-and-amounth disease challenge by 10 days post second vaccination and those of clostridial antitoxin above the level generally considered to be protective. It was concluded that despite the evidence of distinct immunosuppression in cattle from trypanosome endemic areas it unlikely to impede the developement of protection against foot-and-mounth disease and clostridial infection by vaccination.
Palavras-Chave: | Bovine.
Thesagro: | Bovino; Vacina.
Thesaurus Nal: | Trypanosoma.
Categoria do assunto: | --
Registro original: | Embrapa Pantanal (CPAP)
Exemplares: | CPAP - (31307-1) - ADD - SP - PP - SP14750 -  - 14750 - DIS