| |
|
|
|
Registro Completo |
|
Biblioteca(s): |
Embrapa Recursos Genéticos e Biotecnologia. |
|
Data corrente: |
29/03/2007 |
|
Data da última atualização: |
13/07/2022 |
|
Tipo da produção científica: |
Artigo em Periódico Indexado |
|
Autoria: |
GRISI, M. C. M.; SILVA, D. B.; ALVES, R. B. N.; GRACINDO, L. A. M. B.; VIEIRA, R. F. |
|
Título: |
Avaliação de genótipos de Menta (Mentha spp) nas condições do Distrito Federal, Brasil. |
|
Ano de publicação: |
2006 |
|
Fonte/Imprenta: |
Revista Brasileira de Plantas Medicinais, Botucatu, v. 8, n. 4, p. 33-39, 2006. |
|
Idioma: |
Português |
|
Palavras-Chave: |
Caracterização; Characterization; Essential oil; Genetic variability; Mentha spp; Recursos Genéticos; Variabilidade genética. |
|
Thesagro: |
Menta; Óleo Essencial. |
|
Thesaurus Nal: |
genetic resources. |
|
Categoria do assunto: |
-- |
|
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/178137/1/ID-27991-1.pdf
|
|
Marc: |
LEADER 00855naa a2200277 a 4500
001 1187181
005 2022-07-13
008 2006 bl uuuu u00u1 u #d
100 1 $aGRISI, M. C. M.
245 $aAvaliação de genótipos de Menta (Mentha spp) nas condições do Distrito Federal, Brasil.$h[electronic resource]
260 $c2006
650 $agenetic resources
650 $aMenta
650 $aÓleo Essencial
653 $aCaracterização
653 $aCharacterization
653 $aEssential oil
653 $aGenetic variability
653 $aMentha spp
653 $aRecursos Genéticos
653 $aVariabilidade genética
700 1 $aSILVA, D. B.
700 1 $aALVES, R. B. N.
700 1 $aGRACINDO, L. A. M. B.
700 1 $aVIEIRA, R. F.
773 $tRevista Brasileira de Plantas Medicinais, Botucatu$gv. 8, n. 4, p. 33-39, 2006.
Download
Esconder MarcMostrar Marc Completo |
|
Registro original: |
Embrapa Recursos Genéticos e Biotecnologia (CENARGEN) |
|
|
Biblioteca |
ID |
Origem |
Tipo/Formato |
Classificação |
Cutter |
Registro |
Volume |
Status |
URL |
Voltar
|
|
|
Registro Completo
|
Biblioteca(s): |
Embrapa Agroindústria de Alimentos. |
|
Data corrente: |
21/05/2021 |
|
Data da última atualização: |
15/06/2021 |
|
Tipo da produção científica: |
Artigo em Periódico Indexado |
|
Circulação/Nível: |
A - 1 |
|
Autoria: |
NIGRA, A. D.; GUIMAREAES, D. de A. B.; PRUCCA, C. G.; FREITAS-SILVA, O.; TEODORO, A. J.; GIL, G. A. |
|
Afiliação: |
AYELÉN D. NIGRA, Universidad Nacional de Córdoba; DEBORAH DE ALMEIDA BAUER GUIMARÃES, Universidade Federal do Estado do Rio de Janeiro -UNIRIO; CÉSAR G. PRUCCA, Universidad Nacional de Córdoba; OTNIEL FREITAS SILVA, CTAA; ANDERSON J. TEODORO, Universidade Federal do Estado do Rio de Janeiro - UNIRIO; GERMÁN A. GIL, Universidad Nacional de Córdoba. |
|
Título: |
Antitumor Effects of Freeze-Dried Robusta Coffee (Coffea canephora) Extracts on Breast Cancer Cell Lines. |
|
Ano de publicação: |
2021 |
|
Fonte/Imprenta: |
Oxidative Medicine and Cellular Longevity, 2021, ID 5572630, p. 1-16. |
|
DOI: |
https://doi.org/10.1155/2021/5572630 |
|
Idioma: |
Inglês |
|
Notas: |
Research Article. |
|
Conteúdo: |
Coffee consumption is believed to have chemopreventive and chemotherapeutic effects and to contribute to preventing thedevelopment and progression of cancer. However, there is still controversy around these claims. As indicated in our previousworks, diet can influence the risk of breast cancer. Intake of coffee is hypothesized to reduce this risk, but current scientificevidence is not conclusive. This work is aimed at studying the effects of Robusta coffee bean extract on cell viability,proliferation, and apoptosis of different human cancers, especially breast cancer cell lines. To this end, cell viability wasevaluated by Alamar Blue in 2D and 3D models, the cell cycle by PI, apoptosis by annexin V, mitochondrial morphology, andfunctionality by mitoTracker, and colony formation capacity by the clonogenic assay. Green and dark coffee extract significantlyreduced viability in human breast, colorectal, brain, and bone cancer cells. Coffee anticancer activity was clearly evidenced inMDA-MB-231 (ER-) and MCF-7 (ER+) breast cancer cells but not in the normal breast cell line. In addition, coffee extractinduces an increase S phase and a decrease G2/M population in breast cancer cells, affected the mitochondrial morphology, andtriggered apoptosis. MDA-MB-231 breast cancer cells lost their clonogenic capacity after treatment. The antitumor activity wasdemonstrated in both 2D and 3D culture cell models |
|
Thesagro: |
Café Robusta; Câncer; Extrato Vegetal; Grão; Produto de Origem Vegetal. |
|
Thesaurus NAL: |
Food technology. |
|
Categoria do assunto: |
-- |
|
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/223364/1/Antitumor-Effects-of-Freeze-Dried-Robusta-Coffee-Coffea-canephora-Extracts-on-Breast-Cancer-Cell-Lines.pdf
|
|
Marc: |
LEADER 02271naa a2200277 a 4500
001 2131938
005 2021-06-15
008 2021 bl uuuu u00u1 u #d
024 7 $ahttps://doi.org/10.1155/2021/5572630$2DOI
100 1 $aNIGRA, A. D.
245 $aAntitumor Effects of Freeze-Dried Robusta Coffee (Coffea canephora) Extracts on Breast Cancer Cell Lines.$h[electronic resource]
260 $c2021
500 $aResearch Article.
520 $aCoffee consumption is believed to have chemopreventive and chemotherapeutic effects and to contribute to preventing thedevelopment and progression of cancer. However, there is still controversy around these claims. As indicated in our previousworks, diet can influence the risk of breast cancer. Intake of coffee is hypothesized to reduce this risk, but current scientificevidence is not conclusive. This work is aimed at studying the effects of Robusta coffee bean extract on cell viability,proliferation, and apoptosis of different human cancers, especially breast cancer cell lines. To this end, cell viability wasevaluated by Alamar Blue in 2D and 3D models, the cell cycle by PI, apoptosis by annexin V, mitochondrial morphology, andfunctionality by mitoTracker, and colony formation capacity by the clonogenic assay. Green and dark coffee extract significantlyreduced viability in human breast, colorectal, brain, and bone cancer cells. Coffee anticancer activity was clearly evidenced inMDA-MB-231 (ER-) and MCF-7 (ER+) breast cancer cells but not in the normal breast cell line. In addition, coffee extractinduces an increase S phase and a decrease G2/M population in breast cancer cells, affected the mitochondrial morphology, andtriggered apoptosis. MDA-MB-231 breast cancer cells lost their clonogenic capacity after treatment. The antitumor activity wasdemonstrated in both 2D and 3D culture cell models
650 $aFood technology
650 $aCafé Robusta
650 $aCâncer
650 $aExtrato Vegetal
650 $aGrão
650 $aProduto de Origem Vegetal
700 1 $aGUIMAREAES, D. de A. B.
700 1 $aPRUCCA, C. G.
700 1 $aFREITAS-SILVA, O.
700 1 $aTEODORO, A. J.
700 1 $aGIL, G. A.
773 $tOxidative Medicine and Cellular Longevity, 2021, ID 5572630, p. 1-16.
Download
Esconder MarcMostrar Marc Completo |
|
Registro original: |
Embrapa Agroindústria de Alimentos (CTAA) |
|
|
Biblioteca |
ID |
Origem |
Tipo/Formato |
Classificação |
Cutter |
Registro |
Volume |
Status |
Fechar
|
| Expressão de busca inválida. Verifique!!! |
|
|
