Data/hora: 08/06/2024 08:21:45

Biblioteca(s): | Embrapa Agricultura Digital.
Data corrente: | 22/12/2015
Data da última atualização: | 21/01/2020
Autoria: | FULAZ, S. F.; CABRINI, F.; TASIC, L.; BORRO, L.; NESHICH, G.
Afiliação: | STEPHANIE F. FULAZ; FLÁVIA CABRINI; LJUBICA TASIC; LUIZ BORRO; GORAN NESHICH, CNPTIA.
Título: | Computational biology tools in design of an agrochemical against Xyllela fastidiosa.
Ano de publicação: | 2015
Fonte/Imprenta: | In: CONGRESSO DE INICIAÇÃO CIENTIFICA DA UNICAMP, 33., 2015, Campinas. [Proceedings...]. Campinas: Unicamp, 2015.
Descrição Física: | 1 pôster.
DOI: | 10.19146/pibic-2015-38174
Idioma: | Inglês
Conteúdo: | Xylella fastidiosa is a Gram-negative, non-flagellated bacterium that causes CVC in citrus and Pierce?s disease in grapevines. The CVC affects 40% of the 200 million orange trees in São Paulo state. It colonizes the xylem vessels of the plants, blocking the water and nutrient flows. PilT protein is a part of the motility system and very important for Xyllela pathogenicity and our protein target for drug design. Computational biology tools were used to design the compound able to inhibit the formation of the PilT hexamer, leading to loss of Xyllela pathogenicity. This approach could be employed in the development of new inhibitors against different targets belonging to the same protein family of PilT.
Palavras-Chave: | Bioinformática; Biology; Computational biology tools; Ferramentas de biologia computacional; PilT.
Thesagro: | Xylella Fastidiosa.
Thesaurus Nal: | Bioinformatics.
Categoria do assunto: | X Pesquisa, Tecnologia e Engenharia
URL: | http://ainfo.cnptia.embrapa.br/digital/bitstream/item/136081/1/computational-Fulaz-pibic.pdf
Registro original: | Embrapa Agricultura Digital (CNPTIA)
Exemplares: | CNPTIA - (18549-1) - UPC - RA - DD -  -  -  - DIS