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Registro Completo |
Biblioteca(s): |
Embrapa Agricultura Digital; Embrapa Pecuária Sudeste. |
Data corrente: |
28/07/2022 |
Data da última atualização: |
31/08/2022 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Autoria: |
LIMA, A. O.; MALHEIROS, J. M.; AFONSO, J.; PETRINI, J.; COUTINHO, L. L.; DINIZ, W. J. da S.; DONATONI, F. A. B.; TIZIOTO, P. C.; OLIVEIRA, P. S. N. de; RIBEIRO, J. A. S.; OLIVEIRA, K. S. de; ROCHA, M. I. P.; ANDRADE, B. G. N.; FUKUMASU, H.; BEIKI, H.; REECY, J. M.; ZERLOTINI NETO, A.; MOURAO, G. B.; REGITANO, L. C. de A. |
Afiliação: |
ANDRESSA OLIVEIRA LIMA, UFSCAR; JESSICA MORAES MALHEIROS; JULIANA AFONSO; JULIANA PETRINI, ESALQ/USP; LUIZ LEHMANN COUTINHO, ESALQ/USP; WELLISON JARLES DA SILVA DINIZ, UFSCAR; FLAVIA ALINE BRESSANI DONATONI, CPPSE; POLYANA CRISTINE TIZIOTO, NGS SOLUÇÕES GENÔMICAS, PIRACICABA; PRISCILA SILVA NEUBERN DE OLIVEIRA; JANSSEN AYNA SILVA RIBEIRO, UFSCAR; KARINA SANTOS DE OLIVEIRA, UFSCAR; MARINA IBELLI PEREIRA ROCHA, UFSCAR; BRUNO GABRIEL NASCIMENTO ANDRADE, MUNSTER TECHNOLOGICAL UNIVERSITY; HEIDGE FUKUMASU, USP; HAMID BEIKI, IOWA STATE UNIVERSITY; JAMES MARK REECY, IOWA STATE UNIVERSITY; ADHEMAR ZERLOTINI NETO, CNPTIA; GERSON BARRETO MOURAO, ESALQ/USP; LUCIANA CORREIA DE ALMEIDA REGITANO, CPPSE. |
Título: |
Prune homolog 2 with BCH domain (PRUNE2) gene expression is associated with feed efficiency related traits in Nelore steers. |
Ano de publicação: |
2022 |
Fonte/Imprenta: |
Mammalian Genome, 2022. |
DOI: |
https://doi.org/10.1007/s00335-022-09960-1 |
Idioma: |
Inglês |
Conteúdo: |
Abstract. Animal feeding is a critical factor in increasing producer profitability. Improving feed efficiency can help reduce feeding costs and reduce the environmental impact of beef production. Candidate genes previously identified for this trait in differential gene expression studies (e.g., case?control studies) have not examined continuous gene-phenotype variation, which is a limitation. The aim of this study was to investigate the association between the expression of five candidate genes in the liver, measured by quantitative real-time PCR and feed-related traits. We adopted a linear mixed model to associate liver gene expression from 52 Nelore steers with the following production traits: average daily gain (ADG), body weight (BW), dry matter intake (DMI), feed conversion ratio (FCR), feed efficiency (FE), Kleiber index (KI), metabolic body weight (MBW), residual feed intake (RFI), and relative growth ratio (RGR). The total expression of the prune homolog 2 (PRUNE2) gene was significantly associated with DMI, FCR, FE, and RFI (P < 0.05). Furthermore, we have identified a new transcript of PRUNE2 (TCONS_00027692, GenBank MZ041267) that was inversely correlated with FCR and FE (P < 0.05), in contrast to the originally identified PRUNE2 transcript. The cytochrome P450 subfamily 2B (CYP2B6), early growth response protein 1 (EGR1), collagen type I alpha 1 chain (COL1A1), and connective tissue growth factor (CTGF) genes were not associated with any feed efficiency-related traits (P > 0.05). The findings reported herein suggest that PRUNE2 expression levels affects feed efficiency-related traits variation in Nelore steers. MenosAbstract. Animal feeding is a critical factor in increasing producer profitability. Improving feed efficiency can help reduce feeding costs and reduce the environmental impact of beef production. Candidate genes previously identified for this trait in differential gene expression studies (e.g., case?control studies) have not examined continuous gene-phenotype variation, which is a limitation. The aim of this study was to investigate the association between the expression of five candidate genes in the liver, measured by quantitative real-time PCR and feed-related traits. We adopted a linear mixed model to associate liver gene expression from 52 Nelore steers with the following production traits: average daily gain (ADG), body weight (BW), dry matter intake (DMI), feed conversion ratio (FCR), feed efficiency (FE), Kleiber index (KI), metabolic body weight (MBW), residual feed intake (RFI), and relative growth ratio (RGR). The total expression of the prune homolog 2 (PRUNE2) gene was significantly associated with DMI, FCR, FE, and RFI (P < 0.05). Furthermore, we have identified a new transcript of PRUNE2 (TCONS_00027692, GenBank MZ041267) that was inversely correlated with FCR and FE (P < 0.05), in contrast to the originally identified PRUNE2 transcript. The cytochrome P450 subfamily 2B (CYP2B6), early growth response protein 1 (EGR1), collagen type I alpha 1 chain (COL1A1), and connective tissue growth factor (CTGF) genes were not associated with any feed efficiency-related t... Mostrar Tudo |
Palavras-Chave: |
Apoptose; Características relacionadas à alimentação; Expressão gênica no fígado de Nelore; Reação em cadeia da polimerase; Reação em cadeia da polimerase em tempo real; Real-time quantitative PCR. |
Thesagro: |
Fígado; Gado de Corte; Gado Nelore. |
Thesaurus Nal: |
Apoptosis; Beef cattle; Gene expression; Liver; Polymerase chain reaction. |
Categoria do assunto: |
-- G Melhoramento Genético |
Marc: |
LEADER 03224naa a2200517 a 4500 001 2145028 005 2022-08-31 008 2022 bl uuuu u00u1 u #d 024 7 $ahttps://doi.org/10.1007/s00335-022-09960-1$2DOI 100 1 $aLIMA, A. O. 245 $aPrune homolog 2 with BCH domain (PRUNE2) gene expression is associated with feed efficiency related traits in Nelore steers.$h[electronic resource] 260 $c2022 520 $aAbstract. Animal feeding is a critical factor in increasing producer profitability. Improving feed efficiency can help reduce feeding costs and reduce the environmental impact of beef production. Candidate genes previously identified for this trait in differential gene expression studies (e.g., case?control studies) have not examined continuous gene-phenotype variation, which is a limitation. The aim of this study was to investigate the association between the expression of five candidate genes in the liver, measured by quantitative real-time PCR and feed-related traits. We adopted a linear mixed model to associate liver gene expression from 52 Nelore steers with the following production traits: average daily gain (ADG), body weight (BW), dry matter intake (DMI), feed conversion ratio (FCR), feed efficiency (FE), Kleiber index (KI), metabolic body weight (MBW), residual feed intake (RFI), and relative growth ratio (RGR). The total expression of the prune homolog 2 (PRUNE2) gene was significantly associated with DMI, FCR, FE, and RFI (P < 0.05). Furthermore, we have identified a new transcript of PRUNE2 (TCONS_00027692, GenBank MZ041267) that was inversely correlated with FCR and FE (P < 0.05), in contrast to the originally identified PRUNE2 transcript. The cytochrome P450 subfamily 2B (CYP2B6), early growth response protein 1 (EGR1), collagen type I alpha 1 chain (COL1A1), and connective tissue growth factor (CTGF) genes were not associated with any feed efficiency-related traits (P > 0.05). The findings reported herein suggest that PRUNE2 expression levels affects feed efficiency-related traits variation in Nelore steers. 650 $aApoptosis 650 $aBeef cattle 650 $aGene expression 650 $aLiver 650 $aPolymerase chain reaction 650 $aFígado 650 $aGado de Corte 650 $aGado Nelore 653 $aApoptose 653 $aCaracterísticas relacionadas à alimentação 653 $aExpressão gênica no fígado de Nelore 653 $aReação em cadeia da polimerase 653 $aReação em cadeia da polimerase em tempo real 653 $aReal-time quantitative PCR 700 1 $aMALHEIROS, J. M. 700 1 $aAFONSO, J. 700 1 $aPETRINI, J. 700 1 $aCOUTINHO, L. L. 700 1 $aDINIZ, W. J. da S. 700 1 $aDONATONI, F. A. B. 700 1 $aTIZIOTO, P. C. 700 1 $aOLIVEIRA, P. S. N. de 700 1 $aRIBEIRO, J. A. S. 700 1 $aOLIVEIRA, K. S. de 700 1 $aROCHA, M. I. P. 700 1 $aANDRADE, B. G. N. 700 1 $aFUKUMASU, H. 700 1 $aBEIKI, H. 700 1 $aREECY, J. M. 700 1 $aZERLOTINI NETO, A. 700 1 $aMOURAO, G. B. 700 1 $aREGITANO, L. C. de A. 773 $tMammalian Genome, 2022.
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Embrapa Pecuária Sudeste (CPPSE) |
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Registros recuperados : 10 | |
1. | | ALEXANDRE, P.; SANTANA, M. H. A.; GOMES, R. da C.; FERRAZ, J. B. S.; FUKUMASU, H. Molecular characterization of constitutive androstane receptor (CAR) and its association with feed efficiency of Nellore (Bos indicus) cattle. Journal of Animal Science v.90, (Supplement 3/J); Journal of Dairy Science, v.95, (Supplement 2), p.524, 2012. Edição dos trabalhos do: ADSA-PSA-AMPA-ASAS-CSAS-WSASAS JOINT ANNUAL MEETING, 2012, Phoenix-AR. Breeding and Genetics: Molecular Biology and Genomics. W68.Tipo: Resumo em Anais de Congresso |
Biblioteca(s): Embrapa Gado de Corte. |
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2. | | FUKUMASU, H.; AVANZO, J. L.; HEIDOR, R.; SILVA, T. C.; ATROCH, A.; MORENO, F. S.; DAGLI, M. L. Z. Protective effects of guarana (Paullinia cupana Mart. var. Sorbilis) against DEN-induced DNA damage on mouse liver. Food and Chemical Toxicology, v. 44, n. 6 , p. 862-867, jun. 2006.Tipo: Artigo em Periódico Indexado | Circulação/Nível: Internacional - A |
Biblioteca(s): Embrapa Amazônia Ocidental. |
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3. | | SANTOS, Y. J. S.; FACCHINATTO, W. M.; ROCHETTI, A. L.; CARVALHO, R. A.; Le FEUNTEUN; FUKUMASU, H.; MORZEL, M.; COLNAGO, L. A.; VANIN, F. M. Systemic characterization of pupunha (Bactris gasipaes) flour with views of polyphenol content on cytotoxicity and protein in vitro digestion. Food Chemistry, v. 405, 134888, 2023. 9 p.Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
Biblioteca(s): Embrapa Instrumentação. |
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4. | | FUKUMASU, H.; SILVA, T. C. da; AVANZO, J. L.; LIMA, C. E. de; MACKOWIAK, I. I.; ATROCH, A.; SPINOSA, H. de S.; MORENO, F. S.; DAGLI, M. L. Z. Chemopreventive effects of Paullinia cupana Mart var. sorbilis, the guarana, on mouse hepatocarcinogenesis. Cancer Letters, v. 233, n. 1, p. 158-164, fev. 2006.Tipo: Artigo em Periódico Indexado | Circulação/Nível: Internacional - C |
Biblioteca(s): Embrapa Amazônia Ocidental. |
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5. | | ALEXANDRE, P. A.; GOMES, R. da C.; SANTANA, M. H. A.; SILVA, S. L.; LEMES, P. R.; MUDADU, M. de A.; REGITANO, L. C. de A.; MEIRELLES, F. V.; FERRAZ, J. B. S.; FUKUMASU, H. Bovine NR1I3 gene polymorphisms and its association with feed efficiency traits in Nellore cattle. Meta Gene, v. 2, p. 206-217, dec. 2014.Tipo: Artigo em Periódico Indexado |
Biblioteca(s): Embrapa Pecuária Sudeste. |
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6. | | SANTANA, M. H. de A.; OLIVEIRA JUNIOR, G. A.; CESAR, A. S. M.; FREUA, M. C.; GOMES, R. da C.; SILVA, S. da L.; LEME, P. R.; FUKUMASU, H.; CARVALHO, M. E.; VENTURA, R. V.; COUTINHO, L. L.; KADARMIDEEN, H. N.; FERRAZ, J. B. S. Copy number variations and genome-wide associations reveal putative genes and metabolic pathways involved with the feed conversion ratio in beef cattle. Journal of Applied Gentics, v. 57, n. 4, p. 495-504, 2016Tipo: Artigo em Periódico Indexado | Circulação/Nível: B - 1 |
Biblioteca(s): Embrapa Gado de Corte. |
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7. | | LIMA, A. O.; MALHEIROS, J. M.; AFONSO, J.; PETRINI, J.; COUTINHO, L. L.; DINIZ, W. J. da S.; DONATONI, F. A. B.; TIZIOTO, P. C.; OLIVEIRA, P. S. N. de; RIBEIRO, J. A. S.; OLIVEIRA, K. S. de; ROCHA, M. I. P.; ANDRADE, B. G. N.; FUKUMASU, H.; BEIKI, H.; REECY, J. M.; ZERLOTINI NETO, A.; MOURAO, G. B.; REGITANO, L. C. de A. Prune homolog 2 with BCH domain (PRUNE2) gene expression is associated with feed efficiency related traits in Nelore steers. Mammalian Genome, 2022.Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 2 |
Biblioteca(s): Embrapa Agricultura Digital; Embrapa Pecuária Sudeste. |
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8. | | FANALLI, S. L.; SILVA, B. P. M. DA; GOMES, J. D.; CICONELLO, F. N.; ALMEIDA, V. V. DE; FREITAS, F. A. O.; MOREIRA, G. C. M.; VIGNATO, B. S.; AFONSO, J.; REECY, J.; KOLTES, J.; KOLTES, D.; REGITANO, L. C. de A.; BAILEIRO, J. C. DE C.; FREITAS, L.; COUTINHO, L. L.; FUKUMASU, H.; ALENCAR, S. M. DE; LUCHIARI FILHO, A.; CESAR, A. S. M. Effect of dietary soybean oil inclusion on liver-related transcription factors in a pig model for metabolic diseases. Scientific Reports, v. 12, 10318, jun. 2022. 10 p.Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
Biblioteca(s): Embrapa Pecuária Sudeste. |
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9. | | ALMEIDA, V. V.; SILVA, J. P. M.; SCHINCKEL, A. P.; MEIRA, A. N.; MOREIRA, G. C. M.; GOMES, J. D.; POLETI, M. D.; DARGELIO, M. D. B.; PATINHO, I.; CONTRERAS-CASTILLO, C. J.; COUTINHO, L. L.; MOURÃO, G. B.; REECY, J. M.; KOLTES, D.; SERÃO, N. V. L.; REGITANO, L. C. de A.; FUKUMASU, H.; BRUSTOLINI, A. P. L.; ALENCAR, S. M.; LUCHIARI FILHO, A.; CESAR, A. S. M. Effects of increasing dietary oil inclusion from different sources on growth performance, carcass and meat quality traits, and fatty acid profile in genetically lean immunocastrated male pigs. Livestock Science, v.248, jun. 2021, 104515. 10 p.Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 2 |
Biblioteca(s): Embrapa Pecuária Sudeste. |
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10. | | FINALLI, S. L.; SILVA, B. P. M. DA; GOMES, J. D.; ALMEIDA, V. V. DE; FREITAS, F. A. O.; MOREIRA, G. C. M.; VIGNATO, B. S.; AFONSO, J.; REECY, J.; KOLTES, J.; KOLTES, D.; REGITANO, L. C. de A.; GARRICK, D. J.; BALIEIRO, J. C. DE C.; MEIRA, A. N.; FREITAS, L.; COUTINHO, L. L.; FUKUMASU, H.; MOURÃO, G. B.; ALENCAR, S. M. DE; LUCHIARI FILHO, A.; CESAR, A. S. M. Differential gene expression associated with soybean oil level in the diet of pigs. Animals, v. 12, n. 13 1632, jun. 2022. 21 p.Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 2 |
Biblioteca(s): Embrapa Pecuária Sudeste. |
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Registros recuperados : 10 | |
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Nenhum registro encontrado para a expressão de busca informada. |
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