Data/hora: 09/06/2024 21:45:45

Biblioteca(s): 	Embrapa Caprinos e Ovinos.	
Data corrente: 	25/07/2008	
Data da última atualização: 	11/03/2024	
Autoria: 	HUCKE, E. E. T. S.; CRUZ-CASALLA, P. E.; SIDER, L. H.; FELICIO, L. F.	
Título: 	Reproductive experience modulates dopamine-related behavioral responses.	
Ano de publicação: 	2001	
Fonte/Imprenta: 	Pharmacology, Biochemistry and Behavior, v. 68, n. 3, p. 575-582, 2001.	
DOI: 	10.1016/s0091-3057(01)00458-0.	
Idioma: 	Inglês	
Conteúdo: 	Reproductive experience (RE), i.e., mating, pregnancy, parturition and lactation, has long-term physiological effects. It reduces the basal levels of circulating prolactin in parous women, decreases the intensity of nocturnal and diurnal prolactin surges in multigravid rats during early pregnancy, as well as the hormonal and neurochemical responses to the dopamine receptor antagonists metoclopramide and haloperidol. In the present study, we evaluated the possible influences of RE on some dopaminergic-related behaviors: (1) acute responses to a new environment represented by an open-field arena plus injection stress; (2) modulation of behavior after a short-term withdrawal subsequent to 7 days amphetamine (AMPH) pretreatment; (3) stereotypy elicited by AMPH and apomorphine (APO); and (4) APO-induced hypothermia. In the 3-min open-field test, there was a decrease in locomotor activity as a function of RE. Behavioral depression was mild and AMPH pretreatment revealed RE alterations. APO-induced stereotyped behavior was slightly more intense in primiparous animals, although no significant differences were found in AMPH-induced stereotyped behavior. No differences were observed between intact and ovariectomized primiparous and nulliparous animals in APO-induced hypothermia. Our data suggest that RE modifies some DA-related behavioral responses. The physiological relevance of the phenomenon is discussed. D 2001 Elsevier Science Inc. All rights reserved.	
Palavras-Chave: 	Atividade motora; Dopamina; Drug effects; Hipotemia.	
Thesagro: 	Hormônio; Parto; Reprodução Animal.	
Thesaurus Nal: 	Dopamine receptors; Females; Ovariectomy; Parity (reproduction); Physiology; Rats; Sexual behavior.	
Categoria do assunto: 	L Ciência Animal e Produtos de Origem Animal	
Registro original: 	Embrapa Caprinos e Ovinos (CNPC)	
Exemplares: 	CNPC - (21133-1) - ADD - SP - PP - SP 06397 -  - SP 06397 - DES
CNPC - (21133-2) - ADD - AP - DD -  -  -  - DIS