Data/hora: 04/06/2024 11:00:06

Biblioteca(s): 	Embrapa Amazônia Oriental.	
Data corrente: 	07/03/2009	
Data da última atualização: 	22/11/2022	
Autoria: 	FARIA, M. T. de; CALDERWOOD, M. S.; ATHANAZIO, D. A.; MAcBRIDE, A. J. A.; HARTSKEERL, R. A.; PEREIRA, M. M.; KO, A. I.; REIS, M. G.	
Afiliação: 	MARCOS TUCUNDUVA DE FARIA, CPATU; Michael S. Calderwood, Medicine Brigham and Women's Hospital; Daniel A. Athanazio, UFBA; Alan J.A. McBride, Fundação Oswaldo Cruz; Rudy A. Hartskeerl, Royal Tropical Institute; Martha Maria Pereira, Fundação Oswaldo Cruz; Albert I. Ko, Fundação Oswaldo Cruz; Mitermayer G. Reis, Fundação Oswaldo Cruz.	
Título: 	Carriage of Leptospira interrogans among domestic rats from an urban setting highly endemic for leptospirosis in Brazil.	
Ano de publicação: 	2008	
Fonte/Imprenta: 	Acta Tropica, v. 108, n. 1, p. 1-5, 2008.	
DOI: 	http://dx.doi.org/10.1016/j.actatropica.2008.07.005	
Idioma: 	Inglês	
Conteúdo: 	A survey was conducted to identify reservoirs for urban leptospirosis in the city of Salvador, Brazil. Sampling protocols were performed in the vicinity of households of severe leptospirosis cases identified during active hospital-based surveillance. Among a total of 142 captured Rattus norvegicus (Norwegian brown rat), 80.3% had a positive culture isolate from urine or kidney specimens and 68.1% had a positive serum sample by microscopic agglutination test (MAT) titre of ?1:100. Monoclonal antibody-based typing of isolates identified that the agent carried by rats was Leptospira interrogans serovar Copenhageni, which was the same serovar isolated from patients during hospital-based surveillance. Leptospira spp. were not isolated from 8 captured Didelphis marsupialis (Opossum), while 5/7 had a positive MAT titre against a saprophytic serogroup. R. rattus were not captured during the survey. The study findings indicate that the brown rat is a major rodent reservoir for leptospirosis in this urban setting. Furthermore, the high carriage rates of L. interrogans serovar Copenhageni in captured rats suggest that there is a significant degree of environmental contamination with this agent in the household environment of high risk areas, which in turn is a cause of transmission during urban epidemics.	
Palavras-Chave: 	Brasil.	
Thesagro: 	Anatomia Animal; Bactéria; Doença Animal; Leptospirose; Morfologia Animal; Rato.	
Categoria do assunto: 	--	
Registro original: 	Embrapa Amazônia Oriental (CPATU)	
Exemplares: 	CPATU - (40654-1) - UPC - AP - DD -  -  -  - DIS